Education Information
2002 - 2006
2002 - 2006Expertise In Medicine
İstanbul University-Cerrahpaşa, Cerrahpasa Faculty Of Medicine, Department Of Internal Medicine, Turkey
1989 - 1994
1989 - 1994Doctorate
Istanbul University, Turkey
1979 - 1986
1979 - 1986Under Graduate
İstanbul University-Cerrahpaşa, Turkey
Dissertations
2006
2006Expertise In Medicine
SET gene expression in acute leukemia patients
Istanbul University
1994
1994Doctorate
N-myc onkogene amplification in Neuroblastoma and its clinical significance
Istanbul University
Foreign Languages
C1 Advanced
C1 AdvancedEnglish
Research Areas
Health Sciences, Medical Genetics
Academic Titles / Tasks
2016 - Continues
2016 - ContinuesProfessor
Acibadem Mehmet Ali Aydinlar University, School of Medicine, Department of Medical Sciences
2006 - 2007
2006 - 2007Professor
Erasmus Universiteit Rotterdam
Managerial Experience
2020 - Continues
2020 - ContinuesHead of Department
Acibadem Mehmet Ali Aydinlar University, Graduate School of Health Sciences
2017 - Continues
2017 - ContinuesRectorate Commissioner
Acibadem Mehmet Ali Aydinlar University, School of Medicine, Department of Medical Sciences
2017 - Continues
2017 - ContinuesErasmus Coordinator
Acibadem Mehmet Ali Aydinlar University, School of Medicine, Department of Medical Sciences
2017 - Continues
2017 - ContinuesBAP Scientific Commissioner
Acibadem Mehmet Ali Aydinlar University, Additional Departments, ABAPKO
2017 - Continues
2017 - ContinuesRektörlük Kalite Komisyonu Üyesi
Acibadem Mehmet Ali Aydinlar University, School of Medicine, Department of Medical Sciences
2017 - Continues
2017 - ContinuesDirector of the Center
Acibadem Mehmet Ali Aydinlar University, Additional Departments, Rare Disease and Orphan Drugs Application and Research Center
2016 - Continues
2016 - ContinuesDirector of The Institution
Acibadem Mehmet Ali Aydinlar University, Graduate School of Health Sciences
2016 - Continues
2016 - ContinuesHead of Department
Acibadem Mehmet Ali Aydinlar University, School of Medicine, Department of Medical Sciences
2010 - 2016
2010 - 2016Director of The Institution
Istanbul University
Courses
Advising Theses
2016
2016Post Graduate
Yaygın değişken immün yetersizlik (CVID) hastalarında CD19, ICOS, TACI, BAFF-R gen mutasyonlarının araştırılması
Özbek U. (Consultant)
S.SISKO(Student)
2015
2015Doctorate
Çocukluk çağı nüks akut lösemi hastalarında tüm genom analizleri
Özbek U. (Consultant)
Y.ERBİLGİN(Student)
2014
2014Doctorate
Ailesel geçiş gösteren idiyopatik epilepsilerin genetik altyapısının aydınlatılması
Özbek U. (Consultant)
F.NUR(Student)
2013
2013Post Graduate
Stem-loop RT-polimeraz zincir reaksiyonu (PZR) yöntemi ile mikro RNA (miRNA) gen anlatım farklılıklarının tespiti
Özbek U. (Consultant)
N.MAVİ(Student)
2012
2012Post Graduate
T hücreli akut lenfoblastik lösemili hastalarda mikroRNA (miRNA) anlatımının tespiti
Özbek U. (Consultant)
C.ÖZTUNÇ(Student)
2012
2012Post Graduate
İdiyopatik jeneralize epilepsili ailelerde lokus ve gen analizi
Özbek U. (Consultant)
İ.KARACAN(Student)
2012
2012Doctorate
T-hücreli akut lenfoblastik lösemide genom boyu anlatım analizleri
Özbek U. (Consultant)
Ö.HATIRNAZ(Student)
2011
2011Post Graduate
Mezyal temporal lob epilepsisinde apoptoza yol açan genlerin ekspresyonlarının analizi
Özbek U. (Consultant)
E.YÜCESAN(Student)
2010
2010Post Graduate
Temporal lob epilepsi patogenezinde enflamasyonla ilgili genlerin ekspresyonlarının araştırılması
Özbek U. (Consultant)
Ö.ÖZDEMİR(Student)
2010
2010Post Graduate
B hücreli akut lenfoblastik lösemilerde PAX5 geninin araştırılması
Özbek U. (Consultant)
S.ÖZDEMİRLİ(Student)
2009
2009Post Graduate
PINK1 Ve SWAP70 genlerinin klonlanmasıyla oluşturulan proteinlerin behçet hastalarında ELISA yöntemi ile taranması
Özbek U. (Consultant)
E.UĞUREL(Student)
2009
2009Doctorate
Temporal lob epileptogeneziyle ilişkili genlerin ekspresyon analizi
Özbek U. (Consultant)
N.BEBEK(Student)
2008
2008Post Graduate
T-ALL hastalarında NOTCH1 mutasyonunun araştırılması
Özbek U. (Consultant)
Y.ERBİLGİN(Student)
2008
2008Post Graduate
Çocukluk çağı akut myeloid lösemi hastalarında kromozomal değişiklikler ve FLT3 geni mutasyonlarının araştırılması
Özbek U. (Consultant)
E.MEHMET(Student)
2007
2007Doctorate
Akut myeloid lösemi etiyolojisinde MN1 geninin rolü
Özbek U. (Consultant)
S.SIRMA(Student)
2005
2005Doctorate
Behçet hastalığında rol alan yeni immunogenetik antijenlerin SEREX metodu ile belirlenmesi
Özbek U. (Consultant)
B.VURAL(Student)
2003
2003Doctorate
CYP1A1, CYP2D6, CYP2E1, GSTT1 ve GSTM1 gen polimorfizmlerinin akut lösemi etiyolojisindeki rollerinin saptanması
Özbek U. (Consultant)
M.AYDIN(Student)
2003
2003Post Graduate
Sitokin gen polimorfizmlerinin hematopoetik kök hücre nakli sonrası graft-versus-host hastalığı ile ilişkisi
Özbek U. (Consultant)
N.GÜRSES(Student)
2002
2002Post Graduate
Çocukluk çağı obesitesinde glukokortikoid reseptör gen polimorfizminin bazı somatik ve biyokimyasal parametrelerle ilişkisi
Özbek U. (Consultant)
N.ŞEN(Student)
1999
1999Post Graduate
Çocukluk çağı akut lenfoblastik lösemilerinde TEL-AML1 (Translocation Ets Leukemia-Acute Myeloid Leukemia 1) füzyon geni tespiti ve prognostik önemi
Özbek U. (Consultant)
S.SIRMA(Student)
1999
1999Post Graduate
Medüller tiroid karsinomlu olgularda RET (REarranged during transfection) proto-onkogen mutasyonları
Özbek U. (Consultant)
N.BİÇER(Student)
Representation and Promotion Activities
Orphanet Turkey National Coordinator
Institutional Representation, TUSEN, Turkey, İstanbul, 2019 - 2021
Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes
2021
2021The rare rs769301934 variant in NHLRC1 is a common cause of Lafora disease in Turkey.
Haryanyan G., Ozdemir Ö. , Tutkavul K., Dervent A., Ayta S., Ozkara C., et al.
Journal of human genetics, 2021 (Journal Indexed in SCI Expanded)
2021
2021Prognostic evidence of LEF1 isoforms in childhood acute lymphoblastic leukemia
Erbilgin Y., Ng Ö. , Can I., Firtina S., Kucukcankurt F., Karaman S., et al.
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2021 (Journal Indexed in SCI)
2021
2021Preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates
Sir Karakus G., Tastan C., Dilek Kancagi D., Yurtsever B., Tumentemur G. , Demir S., et al.
SCIENTIFIC REPORTS, vol.11, no.1, 2021 (Journal Indexed in SCI)
2020
2020Copy number variations in adult patients with chronic immune thrombocytopenia.
Yucesan E., Hatirnaz N., Yalniz F., Yilmaz H., Salihoglu A., Sudutan T., et al.
Expert review of hematology, 2020 (Journal Indexed in SCI)
2020
2020Hydrogen Sulphide and Nitric Oxide Cooperate in Cardioprotection Against Ischemia/Reperfusion Injury in Isolated Rat Heart
ÜSTÜNOVA S., TAKIR S., YILMAZER N., Bulut H., ALTINDİREK D., HATIRNAZ NG Ö. , et al.
IN VIVO, vol.34, no.5, pp.2507-2516, 2020 (Journal Indexed in SCI)
2020
2020Mutational landscape of severe combined immunodeficiency patients from Turkey
Firtina S., Yin N., Hatirnaz N. , Kiykim A., Aydiner E., Nepesov S., et al.
INTERNATIONAL JOURNAL OF IMMUNOGENETICS, 2020 (Journal Indexed in SCI)
2020
2020PTEN and AKT1 Variations in Childhood T-Cell Acute Lymphoblastic Leukemia
Kucukcankurt F., Erbilgin Y., Firtina S., Hatirnaz Ö. , Karakas Z., Celkan T., et al.
TURKISH JOURNAL OF HEMATOLOGY, vol.37, no.2, pp.98-103, 2020 (Journal Indexed in SCI)
2019
2019Association of genetic variants with colorectal cancer in the extended MENA region: A systematic review.
Sidenna M., Bux R., Fadl T., Ozbek U. , Zayed H.
Current molecular medicine, 2019 (Journal Indexed in SCI)
2019
2019Homozygous c.130-131 ins A (pW44X) mutation in the HAX1 gene as the most common cause of congenital neutropenia in Turkey: Report from the Turkish Severe Congenital Neutropenia Registry.
Karapinar D. Y. , PATIROĞLU T., Metin A., Caliskan U., Celkan T., YILMAZ B., et al.
Pediatric blood & cancer, vol.66, no.10, 2019 (Journal Indexed in SCI)
2019
2019The Impact and Prognostic Significance of Chronic Lymphocytic Leukemia Upregulated 1 (CLLU1) Gene Expression in Patients with Chronic Lymphocytic Leukemia: A Single Center Experience.
Sevinc M., Karabulut A., Eskazan A., Catal T., Ozbek U. , Soysal T.
Laboratory medicine, 2019 (Journal Indexed in SCI Expanded)
2019
2019Prognostic gene alterations and clonal changes in childhood B-ALL
Erbilgin Y., Firtina S., Mercan S., Ng Ö. , Karaman S., Tasar O., et al.
LEUKEMIA RESEARCH, vol.83, 2019 (Journal Indexed in SCI)
2019
2019The Outcomes of Chronic Myeloid Leukemia Patients With Molecular Warning Responses During Imatinib Treatment According to the European LeukemiaNet 2013 Recommendations
Soysal T., Eskazan A. E. , Serin I., Sadri S., Keskin D., Yurttas N. O. , et al.
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, vol.19, no.7, 2019 (Journal Indexed in SCI)
2019
2019Dealing with the gray zones in the management of gastric cancer: The consensus statement of the İstanbul Group.
Aytaç E. , Aslan F., Çicek B., Erdamar S. , Gürses B., Güven K. , et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, vol.30, pp.584-598, 2019 (Journal Indexed in SCI Expanded)
2019
2019Biallelic loss of EEF1D function links heat shock response pathway to autosomal recessive intellectual disability
Iseri S. A. U. , Yucesan E., Tuncer F. N. , ÇALIK M., Kesim Y., Uzun G. A. , et al.
JOURNAL OF HUMAN GENETICS, vol.64, no.5, pp.421-426, 2019 (Journal Indexed in SCI)
2019
2019No evidence for a BRD2 promoter hypermethylation inblood leukocytes of Europeans with juvenile myoclonic epilepsy
Schulz H., Ruppert A., Zara F., Madia F., Iacomino M., Vari M. S. , et al.
EPILEPSIA, vol.60, no.5, 2019 (Journal Indexed in SCI)
2019
2019A Novel and Mosaic WDR45 Nonsense Variant Causes Beta-Propeller Protein-Associated Neurodegeneration Identified Through Whole Exome Sequencing and X chromosome Heterozygosity Analysis.
Akcakaya N. H. , Salman B., Gormez Z., Arguden Y. T. , Cirakoglu A., Cakmur R., et al.
Neuromolecular medicine, vol.21, no.1, pp.54-59, 2019 (Journal Indexed in SCI Expanded)
2019
2019Identification of epilepsy related pathways using genome-wide DNA methylation measures: A trio-based approach.
Ozdemir Ö. , Egemen E., Iseri S. A. U. , SEZERMAN O. U. , Bebek N., Baykan B., et al.
PloS one, vol.14, no.2, 2019 (Journal Indexed in SCI Expanded)
2019
2019Deep sequencing of BCR-ABL1 kinase domain mutations in chronic myeloid leukemia patients with resistance to tyrosine kinase inhibitors
Erbilgin Y., Eskazan A. E. , Ng Ö. , Salihoglu A., Elverdi T., Firtina S., et al.
LEUKEMIA & LYMPHOMA, vol.60, no.1, pp.200-207, 2019 (Journal Indexed in SCI)
2019
2019Clinical and genetic spectrum of an orphan disease MPAN: a series with new variants and a novel phenotype.
Akçakaya N. H. , Haryanyan G., Mercan S., Sozer N., Ali A., Tombul T., et al.
Neurologia i neurochirurgia polska, vol.53, pp.476-483, 2019 (Journal Indexed in SCI Expanded)
2019
2019; The Role of the Local Bone Marrow Renin-Angiotensin System in Multiple Myeloma
Sakai B., Sayitoglu M., Istemihan Z., Karan M. A. , Erten N., Dogan O., et al.
TURKISH JOURNAL OF HEMATOLOGY, vol.36, no.3, pp.178-185, 2019 (Journal Indexed in SCI)
2018
2018Frontline nilotinib treatment in Turkish patients with Philadelphia chromosome-positive chronic Myeloid Leukemia in chronic phase: updated results with 2 years of follow-up
SAYDAM G., HAZNEDAROĞLU İ. C. , KAYNAR L., Yavuz A., Ali R., GÜVENÇ B., et al.
HEMATOLOGY, vol.23, no.10, pp.771-777, 2018 (Journal Indexed in SCI)
2018
2018Investigation of SLC2A1 gene variants in genetic generalized epilepsy patients with eyelid myoclonia.
Altiokka-Uzun G., Ozdemir Ö. , Ugur-Iseri S., Bebek N., Gurses C., Ozbek U. , et al.
Epileptic disorders : international epilepsy journal with videotape, vol.20, no.5, pp.396-400, 2018 (Journal Indexed in SCI Expanded)
2018
2018Rare coding variants in genes encoding GABA(A) receptors in genetic generalised epilepsies: an exome-based case-control study
May P., Girard S., Harrer M., Bobbili D. R. , Schubert J., Wolking S., et al.
LANCET NEUROLOGY, vol.17, no.8, pp.699-708, 2018 (Journal Indexed in SCI)
2018
2018Clinical phenotype of hereditary spastic paraplegia due to KIF1C gene mutations across life span
YÜCEL YILMAZ D., Yucesan E., YALNIZOĞLU D., Oguz K. K. , Sagiroglu M. S. , Ozbek U. , et al.
BRAIN & DEVELOPMENT, vol.40, no.6, pp.458-464, 2018 (Journal Indexed in SCI)
2018
2018Association of Pro-apoptotic Bad Gene Expression Changes with Benign Thyroid Nodules
Gul N., Temel B., Ustek D., Sirma-Ekmekci S., Kapran Y., Tunca F., et al.
IN VIVO, vol.32, no.3, pp.555-559, 2018 (Journal Indexed in SCI)
2018
2018Outcomes with frontline nilotinib treatment in Turkish patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase.
Saydam G., Haznedaroglu I., Kaynar L., Yavuz A., Ali R., Guvenc B., et al.
Hematology (Amsterdam, Netherlands), pp.1-7, 2018 (Journal Indexed in SCI)
2018
2018Third-line treatment with second-generation tyrosine kinase inhibitors (dasatinib or nilotinib) in patients with chronic myeloid leukemia after two prior TKIs: real-life data on a single center experience along with the review of the literature
Ongoren S., Eskazan A. E. , Suzan V., Savci S., Ozunal I. E. , Berk S., et al.
HEMATOLOGY, vol.23, no.4, pp.212-220, 2018 (Journal Indexed in SCI)
2017
2017SYNE1 related cerebellar ataxia presents with variable phenotypes in a consanguineous family from Turkey
Yucesan E., Iseri S. A. U. , Bilgic B., Gormez Z., Gungor B. B. , Sarac A., et al.
NEUROLOGICAL SCIENCES, vol.38, no.12, pp.2203-2207, 2017 (Journal Indexed in SCI)
2017
2017Outcomes of Chronic Myeloid Leukemia Patients With Early Molecular Response at 3 and 6 Months: A Comparative Analysis of Generic Imatinib and Glivec
Eskazan A. E. , Sadri S., Keskin D., Ayer M., Kantarcioglu B., Demirel N., et al.
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, vol.17, no.12, pp.804-811, 2017 (Journal Indexed in SCI)
2017
2017A novel pathogenic frameshift variant of CD3E gene in two T-B+ NK+ SCID patients from Turkey.
Firtina S., Ng Y. Y. , Ng Ö. , Nepesov S., Yesilbas O., Kilercik M. , et al.
Immunogenetics, vol.69, no.10, pp.653-659, 2017 (Journal Indexed in SCI)
2017
2017Clinical and genetic features of PKAN patients in a tertiary centre in Turkey.
Akcakaya N. H. , Iseri S. U. , Bilir B., Battaloglu E., Tekturk P., GÜLTEKİN M., et al.
Clinical neurology and neurosurgery, vol.154, pp.34-42, 2017 (Journal Indexed in SCI Expanded)
2017
2017Aberrant Hypermethylation of APC Tumor Supressor Gene in Acute Leukemia Patients
Hatirnaz Ö. , Firtina S., Erbilgin Y., ÖZBEK U. , Sayitoglu M.
UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, vol.27, no.1, pp.1-7, 2017 (Journal Indexed in SCI)
2017
2017Dysregulation of the DKK1 gene in pediatric B-cell acute lymphoblastic leukemia
Firtina S., Hatirnaz Ng Ö. , Erbilgin Y., Ozbek U. , Sayitoglu M.
TURKISH JOURNAL OF MEDICAL SCIENCES, vol.47, no.1, pp.357-363, 2017 (Journal Indexed in SCI)
2016
2016Outcomes with frontline nilotinib treatment in Turkish patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase
SAYDAM G., HAZNEDAROĞLU İ. C. , KAYNAR L., Yavuz A., Ali R., GÜVENÇ B., et al.
EXPERT OPINION ON PHARMACOTHERAPY, vol.17, no.14, pp.1851-1858, 2016 (Journal Indexed in SCI)
2016
2016A novel gene mutation in PANK2 in a patient with severe jaw-opening dystonia.
Yapici Z., Akcakaya N. H. , Tekturk P., Iseri S. A. U. , Ozbek U.
Brain & development, vol.38, no.8, pp.755-8, 2016 (Journal Indexed in SCI Expanded)
2016
2016Imatinib reduces bone marrow fibrosis and overwhelms the adverse prognostic impact of reticulin formation in patients with chronic myeloid leukaemia
Simsek E. T. , Eskazan A. E. , Cengiz M., Ar M. C. , Ekizoglu S., Salihoglu A., et al.
JOURNAL OF CLINICAL PATHOLOGY, vol.69, no.9, pp.810-816, 2016 (Journal Indexed in SCI)
2016
2016The frequency of C609T polymorphism in the NQO1 gene and its relation to cytogenetic abnormalities in patients with myelodysplastic syndrome
Bagatir G., Sirma S., Palanduz S., Öztürk S., Cefle K., Ozbek U. , et al.
CELLULAR AND MOLECULAR BIOLOGY, vol.62, no.7, pp.61-65, 2016 (Journal Indexed in SCI)
2016
2016Screening LGI1 in a cohort of 26 lateral temporal lobe epilepsy patients with auditory aura from Turkey detects a novel de novo mutation.
Kesim Y. F. , Uzun G. A. , Yucesan E., Tuncer F. N. , Ozdemir Ö. , Bebek N., et al.
Epilepsy research, vol.120, pp.73-8, 2016 (Journal Indexed in SCI Expanded)
2015
2015Investigation of the possible association of NEDD4-2 (NEDD4L) gene with idiopathic photosensitive epilepsy.
Vanli-Yavuz E. N. , Ozdemir Ö. , Demirkan A., Catal S., Bebek N., Ozbek U. , et al.
Acta neurologica Belgica, vol.115, no.3, pp.241-5, 2015 (Journal Indexed in SCI Expanded)
2015
2015High MN1 expression increases the in vitro clonogenic activity of primary mouse B-cells
Numata M., Yener M. D. , Ekmekci S. S. , Aydin M., Grosveld G., Cardone M., et al.
LEUKEMIA RESEARCH, vol.39, no.8, pp.906-912, 2015 (Journal Indexed in SCI)
2015
2015A clinical variant in SCN1A inherited from a mosaic father cosegregates with a novel variant to cause Dravet syndrome in a consanguineous family
Tuncer F. N. , Gormez Z., Calik M., Uzun G. A. , Sagiroglu M. S. , Yuceturk B., et al.
EPILEPSY RESEARCH, vol.113, pp.5-10, 2015 (Journal Indexed in SCI)
2015
2015herg1b Expression as a Potential Specific Marker in Pediatric Acute Myeloid Leukemia Patients with HERG 897K/K Genotype
Erdem M., Tekiner T. A. , Fejzullahu A., Akan G., Anak S., Saribeyoglu E. T. , et al.
PEDIATRIC HEMATOLOGY AND ONCOLOGY, vol.32, no.3, pp.182-192, 2015 (Journal Indexed in SCI)
2015
2015A certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real-time quantitative PCR
White H., Deprez L., Corbisier P., Hall V., Lin F., Mazoua S., et al.
LEUKEMIA, vol.29, no.2, pp.369-376, 2015 (Journal Indexed in SCI)
2015
2015A Possible Role for WNT5A Hypermethylation in Pediatric Acute Lymphoblastic Leukemia
Ng Ö. , Firtina S., Can I., Karakas Z., Agaoglu L., Dogru O., et al.
TURKISH JOURNAL OF HEMATOLOGY, vol.32, no.2, pp.127-135, 2015 (Journal Indexed in SCI)
2014
2014Nilotinib Results in Improved Rates of Molecular Response in Turkish Newly Diagnosed CML-CP Patients: A 24-Month Update
SAYDAM G., HAZNEDAROĞLU İ. C. , KAYNAR L., Yavuz A., Ali R., GÜVENÇ B., et al.
BLOOD, vol.124, no.21, 2014 (Journal Indexed in SCI)
2014
2014The efficacy of generic formulations of imatinib mesylate in the treatment of chronic myeloid leukemia
Eskazan A. E. , Elverdi T., Yalniz F. F. , Salihoglu A., Ar M. C. , Aydin S. O. , et al.
LEUKEMIA & LYMPHOMA, vol.55, no.12, pp.2935-2937, 2014 (Journal Indexed in SCI)
2014
2014First line treatment of chronic phase chronic myeloid leukaemia patients with the generic formulations of imatinib mesylate
Eskazan A. E. , Ayer M., Kantarcioglu B., Arica D., Demirel N., Aydin D., et al.
BRITISH JOURNAL OF HAEMATOLOGY, vol.167, no.1, pp.139-141, 2014 (Journal Indexed in SCI)
2014
2014Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia
Ng Ö. , Erbilgin Y., Firtina S., Celkan T., Karakas Z., Aydogan G., et al.
Blood Cancer Journal, vol.4, no.3, 2014 (Journal Indexed in SCI)
2014
2014Parathyroid allotransplantation in rabbits without cultivation
Can I., Aysan E., Yucesan E., Sayitoglu M., Ozbek U. , Ercivan M., et al.
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol.7, no.1, pp.280-284, 2014 (Journal Indexed in SCI)
2014
2014Local renin-angiotensin system in normal hematopoietic and multiple myeloma-related progenitor cells Normal hematopoetik ve multipl myelom i̇lişkili progenitor hücrelerde lokal renin-anjiotensin sistemi
Uz B., Tatonyan S. C. , Sayitoglu M., Erbilgin Y., Hatirnaz Ö. , AKSU S., et al.
Turkish Journal of Hematology, vol.31, no.2, pp.136-142, 2014 (Journal Indexed in SCI)
2014
2014Chronic myeloid leukemia patients who develop grade I/II pleural effusion under second-line dasatinib have better responses and outcomes than patients without pleural effusion
Eskazan A. E. , Eyice D., Kurt E. A. , Elverdi T., Yalniz F. F. , Salihoglu A., et al.
Leukemia Research, vol.38, no.7, pp.781-787, 2014 (Journal Indexed in SCI)
2013
2013Renin-angiotensin system (RAS) expressions in myeloid leukemic cell lines Miyeloid lösemik hücre dizilerinde renin-anjiyotensin sistem (RAS) ekspresyonlari{dotless}
Uz B., Tatonyan S. C. , Sayitoglu M., Erbilgin Y., Hatirnaz Ng Ö. , BÜYÜKAŞIK Y., et al.
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, vol.23, no.4, pp.264-268, 2013 (Journal Indexed in SCI)
2013
2013Local hematopoietic renin-angiotensin system in myeloid versus lymphoid hematological neoplastic disorders
Uz B., Tatonyan S. C. , Sayitoglu M., Erbilgin Y., Ng O. H. , Buyukasik Y., et al.
JRAAS - Journal of the Renin-Angiotensin-Aldosterone System, vol.14, no.4, pp.308-314, 2013 (Journal Indexed in SCI)
2013
2013Expression analysis and clinical correlation of aquaporin 1 and 4 genes in human hippocampal sclerosis
Bebek N., Özdemir Ö., Sayitoglu M., Hatirnaz Ö. , Baykan B., Gurses C., et al.
Journal of Clinical Neuroscience, vol.20, no.11, pp.1564-1570, 2013 (Journal Indexed in SCI)
2013
2013LOW PLATELET COUNTS AS A PROGNOSTIC MARKER IN ALL TREATMENT IN PLACE OF MRD IN COUNTRIES WITH LIMITED FINANCIAL RESOURCES
Celkan T., Koka A., Özdemir N., Tuysuz G., Apak H., Erginoz E., et al.
PEDIATRIC BLOOD & CANCER, vol.60, pp.191, 2013 (Journal Indexed in SCI)
2013
2013The role of MDR1 C3435T Gene polymorphism on gingival hyperplasia in turkish renal transplant patients treated with cyclosporine in the absence of calcium channel blockers
Kazancioglu H., AK G., Turkmen A., Ozbek U. , Tuncer F., Karabulut A.
Transplantation Proceedings, vol.45, no.6, pp.2233-2237, 2013 (Journal Indexed in SCI)
2013
2013Mediastinal adipose tissue expresses a pathogenic profile of 11 β-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease
Atalar F., Gormez S. , Caynak B., Akan G., Tanriverdi G., Bilgic-Gazioglu S., et al.
Cardiovascular Pathology, vol.22, no.3, pp.183-188, 2013 (Journal Indexed in SCI)
2013
2013Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy.
Møller R., Weber Y., Klitten L., Trucks H., Muhle H., Kunz W., et al.
Epilepsia, vol.54, pp.256-64, 2013 (Journal Indexed in SCI)
2013
2013Association of MDR1 Gene Polymorphism in Patients With Temporal Lobe Epilepsy
ÇİNE N., Sargin G., Bebek N., Gurses C., Baykan B., Ozbek U. , et al.
JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.30, no.1, pp.4-11, 2013 (Journal Indexed in SCI)
2013
2013Identification of Interconnected Markers for T-Cell Acute Lymphoblastic Leukemia
Maiorov E. G. , Keskin O., Ng Ö. , Ozbek U. , Gursoy A.
BIOMED RESEARCH INTERNATIONAL, 2013 (Journal Indexed in SCI)
2012
2012Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32
Steffens M., Leu C., Ruppert A., Zara F., Striano P., Robbiano A., et al.
Human Molecular Genetics, vol.21, no.24, pp.5359-5372, 2012 (Journal Indexed in SCI)
2012
2012Upregulation of T-Cell-Specific Transcription Factor Expression in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)
Sayitoglu M., Erbilgin Y., Ng Ö. , Yildiz I., Celkan T., Anak S., et al.
TURKISH JOURNAL OF HEMATOLOGY, vol.29, no.4, pp.325-333, 2012 (Journal Indexed in SCI)
2012
2012The Nuclear Effector of Wnt-Signaling, Tcf1, Functions as a T-Cell-Specific Tumor Suppressor for Development of Lymphomas
Tiemessen M. M. , Baert M. R. M. , Schonewille T., Brugman M. H. , Famili F., Salvatori D. C. F. , et al.
PLOS BIOLOGY, vol.10, no.11, 2012 (Journal Indexed in SCI)
2012
2012Bromodomain-containing protein 2 gene in photosensitive epilepsy.
Yavuz E. N. , Ozdemir Ö. , Catal S., Bebek N., Ozbek U. , Baykan B.
Seizure, vol.21, no.8, pp.646-8, 2012 (Journal Indexed in SCI Expanded)
2012
2012The role of mediastinal adipose tissue 11β-hydroxysteroid d ehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease
Atalar F., Gormez S. , Caynak B., Akan G., Tanriverdi G., Bilgic-Gazioglu S., et al.
Cardiovascular Diabetology, vol.11, 2012 (Journal Indexed in SCI)
2012
2012Comparison of Apoptotic Gene Expression Profiles Between Peyronie's Disease Plaque and Tunica Albuginea
Zorba O. U. , Sirma S., Ozgon G., Salabas E., Ozbek U. , Kadioglu A.
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.21, no.5, pp.607-614, 2012 (Journal Indexed in SCI)
2012
2012Elevated TRIB2 with NOTCH1 activation in paediatric/adult T-ALL
Hannon M. M. , Lohan F., Erbilgin Y., Sayitoglu M., O'Hagan K., Mills K., et al.
BRITISH JOURNAL OF HAEMATOLOGY, vol.158, no.5, pp.626-634, 2012 (Journal Indexed in SCI)
2012
2012Evaluation of glutathione S-transferase P1 polymorphisms (Ile105Val and Ala114Val) in patients with small cell lung cancer
Vural B., Yakar F., Derin D., Saip P., Yakar A., Demirkan A., et al.
Genetic Testing and Molecular Biomarkers, vol.16, no.7, pp.701-706, 2012 (Journal Indexed in SCI)
2012
2012Investigation of Arg399Gln and Arg194Trp Polymorphisms of the XRCC1 (X-Ray Cross-Complementing Group 1) Gene and Its Correlation to Sister Chromatid Exchange Frequency in Patients with Chronic Lymphocytic Leukemia
Duman N., Aktan M., Ozturk S., Palanduz S., Cakiris A., Ustek D., et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS, vol.16, no.4, pp.287-291, 2012 (Journal Indexed in SCI)
2012
2012SET oncogene is upregulated in pediatric acute lymphoblastic leukemia
Ekmekci S. S. , Ekmekci C. G. , Kandilci A., Gulec C., Akbiyik M., Emrence Z., et al.
Tumori, vol.98, no.2, pp.252-256, 2012 (Journal Indexed in SCI)
2012
2012Estimating the Allele Frequency of Autosomal Recessive Disorders through Mutational Records and Consanguinity: The Homozygosity Index (HI)
Gialluisi A., Pippucci T., Anikster Y., Ozbek U. , Medlej-Hashim M., Mégarbané A., et al.
Annals of Human Genetics, vol.76, no.2, pp.159-167, 2012 (Journal Indexed in SCI)
2012
2012Genetic alterations in members of the Wnt pathway in acute leukemia
Erbilgin Y., Ng Ö. , Mavi N., Ozbek U. , Sayitoglu M.
Leukemia and Lymphoma, vol.53, no.3, pp.508-510, 2012 (Journal Indexed in SCI)
2012
2012Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies
Leu C., de Kovel C. G. F. , Zara F., Striano P., Pezzella M., Robbiano A., et al.
EPILEPSIA, vol.53, no.2, pp.308-318, 2012 (Journal Indexed in SCI)
2012
2012Evaluation of PAX5 gene in the early stages of leukemic B cells in the childhood B cell acute lymphoblastic leukemia.
Firtina S., Sayitoglu M., Hatirnaz Ö. , Erbilgin Y., Oztunc C., Cinar S., et al.
Leukemia research, vol.36, no.1, pp.87-92, 2012 (Journal Indexed in SCI)
2012
201211β-hydroxysteroid dehydrogenase type 1 gene expression is increased in ascending aorta tissue of metabolic syndrome patients with coronary artery disease.
ATALAR F., Vural B., Ciftci C., Demirkan A., Akan G., Susleyici-Duman B., et al.
Genetics and molecular research : GMR, vol.11, no.3, pp.3122-3132, 2012 (Journal Indexed in SCI)
2012
2012Analysis of chromosomal aberrations and FLT3 gene mutations in childhood acute myelogenous leukemia patients Çocukluk Çaǧı Akut Myeloid Lösemi Hastalarında Kromozomal Deǧişiklikler ve FLT3 Geni Mutasyonlarının Araştırılması
Coşkunpinar E., Anak S., Aǧaoǧlu L., Ünüvar A., Devecioǧlu O., Aydoǧan G., et al.
Turkish Journal of Hematology, vol.29, no.3, pp.225-232, 2012 (Journal Indexed in SCI)
2011
2011Anti-neuronal and stress-induced-phosphoprotein 1 antibodies in neuro-Behcet's disease
Vural B., Ugurel E., Tuzun E., Kurtuncu M., Zuliani L., Cavus F., et al.
JOURNAL OF NEUROIMMUNOLOGY, vol.239, pp.91-97, 2011 (Journal Indexed in SCI)
2011
2011Chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation are resistant to dasatinib: Is that true for all the patients?
Eskazan A. E. , Soysal T., ERBİLGİN Y., Ozbek U. , Ferhanoglu B.
Leukemia Research, vol.35, no.9, 2011 (Journal Indexed in SCI)
2011
2011Development of standardized approaches to reporting of minimal residual disease data using a reporting software package designed within the European LeukemiaNet
Ostergaard M., Nyvold C. G. , Jovanovic J. V. , Andersen M. T. , Kairisto V., Morgan Y. G. , et al.
LEUKEMIA, vol.25, no.7, pp.1168-1173, 2011 (Journal Indexed in SCI)
2011
2011Adipose tissue gene expression of adiponectin, tumor necrosis factor-α and leptin in metabolic syndrome patients with coronary artery disease
Gormez S. , Demirkan A., Atalar F., Caynak B., Erdim R. , Sozer V., et al.
Internal Medicine, vol.50, no.8, pp.805-810, 2011 (Journal Indexed in SCI)
2011
2011Glutathione S-transferase P1 polymorphisms are associated with time to tumor progression in small cell lung cancer patients
SAİP P. M. , Sen F., VURAL B., Ugurel E., Demirkan A., Derin D., et al.
Journal of B.U.ON., vol.16, no.2, pp.241-246, 2011 (Journal Indexed in SCI)
2011
2011Investigation of the relationship between clinical and EEG findings of photosensitive epilepsy and GABA receptor alpha 1 subunit (GABRA1) gene mutations Fotosensitif epilepsilerde klinik ve EEG bulgularının GABA reseptör alfa 1 alt ünitesi (GABRA1) geni mutasyonları ile i̇lişkisinin araştırılması
Yavuz E. N. , Demirkan A., Moen S., Özdemir Ö., Çatal S., Bebek N., et al.
Noropsikiyatri Arsivi, vol.48, no.1, pp.39-43, 2011 (Journal Indexed in SCI)
2011
2011ABL gene kinase domain mutation scanning by denaturing high performance liquid chromatography sequencing method Denatüre edici yüksek performanslı likit kromotografi yöntemi ile ABL geni kinaz bölgesi mutasyonlarının taranması
Erbilgin Y., Catal S., Eskazan A. E. , Hatirnaz Ö. , Soysal T., Ozbek U.
Turkish Journal of Hematology, vol.28, no.2, pp.97-102, 2011 (Journal Indexed in SCI)
2010
2010AUTOANTIBODY RESPONSES AGAINST PINK1 AND SWAP70 ANTIGENS IN BEHCET'S DISEASE
Ugurel E., Vural B., Cavus F., Ozbek U. , Gül A., Gure A. O.
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.28, no.4, 2010 (Journal Indexed in SCI)
2010
2010BsmI polymorphism in the vitamin D receptor gene is associated with leg extensor muscle strength in elderly men
Bahat G., Saka B., Erten N., Ozbek U. , Coskunpinar E., Yildiz S., et al.
AGING CLINICAL AND EXPERIMENTAL RESEARCH, vol.22, no.3, pp.198-205, 2010 (Journal Indexed in SCI)
2010
2010Two four-marker haplotypes on 7q36.1 region indicate that the potassium channel gene HERG1 (KCNH2, Kv11.1) is related to schizophrenia: A case control study
ATALAR F., Acuner T. T. , ÇİNE N., Oncu F., Yesilbursa D., Ozbek U. , et al.
Behavioral and Brain Functions, vol.6, 2010 (Journal Indexed in SCI)
2010
2010Association between glutathione s-transferase P1 polymorphisms and time to tumor progression in small cell lung cancer patients.
Saip P., Sen F., Vural B., Ugurel E., Demirkan A., Derin D., et al.
JOURNAL OF CLINICAL ONCOLOGY, vol.28, no.15, 2010 (Journal Indexed in SCI)
2009
2009Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: A European LeukemiaNet Study
Baccarani M., Rosti G., Castagnetti F., Haznedaroglu I., Porkka K., Abruzzese E., et al.
Blood, vol.113, no.19, pp.4497-4504, 2009 (Journal Indexed in SCI)
2009
2009Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behçet's disease
VURAL B., Demirkan A., Ugurel E., Kalaylioglu-Wheeler Z., Esen B. A. , Gure A. O. , et al.
Clinical and Experimental Rheumatology, vol.27, 2009 (Journal Indexed in SCI Expanded)
2009
2009Effects of imatinib mesylate on Renin-Angiotensin System (RAS) activity during the clinical course of chronic myeloid leukaemia
Sayitoglu M., Haznedaroǧlu I. C. , Hatirnaz O., Erbilgin Y., Aksu S., Koca E., et al.
Journal of International Medical Research, vol.37, no.4, pp.1018-1028, 2009 (Journal Indexed in SCI)
2009
2009Comparison of the cytogenetic and molecular analyses in the assessment of imatinib response in chronic myelocytic leukemia.
Palanduz S., Bayrak A., Sirma S., Vural B., Cefle K., Ucur A., et al.
Genetic testing and molecular biomarkers, vol.13, no.5, pp.599-602, 2009 (Journal Indexed in SCI)
2008
2008BDNF gene polymorphism in patients with temporal lobe epilepsy
Sargin G., Gürses C., ÇİNE N., Bebek N., Baykan B., Özbek U. , et al.
Journal of Neurological Sciences, vol.25, no.4, pp.220-225, 2008 (Journal Indexed in SCI)
2008
2008Presence of fatty-acid-binding protein 4 expression in human epicardial adipose tissue in metabolic syndrome
VURAL B., ATALAR F., Ciftci C., Demirkan A., Susleyici-Duman B., Gunay D., et al.
Cardiovascular Pathology, vol.17, no.6, pp.392-398, 2008 (Journal Indexed in SCI)
2008
2008Cloning of chimerical translocations as positive control for molecular genetic diagnosis of leukemia
Ustek D., Sirma S., Cakiris A., Coşan F., Oku B., Özbek U.
Turkish Journal of Hematology, vol.25, no.1, pp.20-23, 2008 (Journal Indexed in SCI Expanded)
2008
2008Vitamin D receptor gene polymorphisms in childhood tuberculosis
Palanduz A., Ozbek U. , Sirma S., Coskunpinar E., Telhan L., Kadioglu L. E. , et al.
ACTA PAEDIATRICA, vol.97, pp.188, 2008 (Journal Indexed in SCI)
2008
20081007fs, G908R, R702W mutations and P268S, IVS8(+158) polymorphisms of the CARD15 gene in Turkish inflammatory bowel disease patients and their relationship with disease-related surgery
Ince A. T. , Hatirnaz Ö. , Ovunc O., Ozbek U.
DIGESTIVE DISEASES AND SCIENCES, vol.53, no.6, pp.1683-1692, 2008 (Journal Indexed in SCI)
2008
2008Localization of the ergtoxin-1 receptors on the voltage sensing domain of hERG K+ channel by AFM recognition imaging
Chtcheglova L. A. , Atalar F., Ozbek U. , Wildling L., Ebner A., Hinterdorfer P.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, vol.456, no.1, pp.247-254, 2008 (Journal Indexed in SCI)
2008
2008Aromatase cytochrome P450 enzyme expression in human pituitary
Kadioglu P., Oral G., SAYİTOĞLU M., Erensoy N., Senel B., Gazioglu N., et al.
Pituitary, vol.11, no.1, pp.29-35, 2008 (Journal Indexed in SCI)
2008
2008Prognostic and predictive value of vascular endothelial growth factor and its soluble receptors, VEGFR-1 and VEGFR-2 levels in the sera of small cell lung cancer patients.
Ustuner Z., Saip P., Yasasever V., VURAL B., Yazar A. , Bal C., et al.
Medical oncology (Northwood, London, England), vol.25, no.4, pp.394-9, 2008 (Journal Indexed in SCI)
2007
2007Definition of C282Y mutation in a hereditary hemochromatosis family from Turkey
Yoenal O., Hatirnaz Ö. , Akyuez F., Koroglu G., Ozbeik U. , Cefle K., et al.
Turkish Journal of Gastroenterology, vol.18, no.1, pp.53-57, 2007 (Journal Indexed in SCI)
2007
2007HFE gene mutation, chronic liver disease, and iron overload in Turkey
Yoenal O., Hatirnaz Ö. , Akyuez F., Oezbek U. , Demir K., Kaymakoglu S., et al.
Digestive Diseases and Sciences, vol.52, no.11, pp.3298-3302, 2007 (Journal Indexed in SCI)
2007
2007Altered cyclin D1 genotype distribution in human sporadic pituitary adenomas
Gazioglu N., Erensoy N., Kadioglu P., Sayitoglu M. A. , Ersoy I. H. , Hatirnaz O., et al.
Medical Science Monitor, vol.13, no.10, 2007 (Journal Indexed in SCI)
2007
2007Angiotensinogen M235T polymorphism and left ventricular indices in treated hypertensive patients with normal coronary arteries
Olkay A., Nişansi Y., Ekmekçi C. G. , Özbek U. , Sezer M., Umman B., et al.
Anadolu Kardiyoloji Dergisi, vol.7, no.3, pp.257-261, 2007 (Journal Indexed in SCI)
2007
2007The SOCS-1 gene methylation in chronic myeloid leukemia patients
Hatirnaz M. , Ure U., Ar C., Akyerli C. , Soysal T., Ferhanoglu B., et al.
American Journal of Hematology, vol.82, no.8, pp.729-730, 2007 (Journal Indexed in SCI)
2007
2007Autologous stem cells collected after debulking by high dose chemotherapy in late phase chronic myeloid leukemia may improve Imatinib efficacy
Kalayoglu-Besisik S., Ozturk G. B. , Caliskan Y., NALÇACI M., Gurses N., Cin N., et al.
Transfusion and Apheresis Science, vol.36, no.1, pp.91-94, 2007 (Journal Indexed in SCI)
2007
2007Association between reduced levels of MEFV messenger RNA in peripheral blood leukocytes and acute inflammation
Üstek D., Ekmekci C. G. , Selçukbiricik F., ÇAKİRİS A., Oku B., VURAL B., et al.
Arthritis and Rheumatism, vol.56, no.1, pp.345-350, 2007 (Journal Indexed in SCI)
2007
2007SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice
Özbek U. , Kandilci A., Van Baal S., Bonten J., Boyd K., Franken P., et al.
American Journal of Pathology, vol.171, no.2, pp.654-666, 2007 (Journal Indexed in SCI)
2006
2006Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients: Effect of ecNOS polymorphism on left ventricular hypertrophy
Olcay A., Ekmekci C. G. , Ozbek U. , Sezer M., Barcin C., Arslan E., et al.
Cardiovascular Ultrasound, vol.4, 2006 (Journal Indexed in SCI Expanded)
2006
2006Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias
Aydin-Sayitoglu M., Hatirnaz Ö. , Erensoy N., Ozbek U.
AMERICAN JOURNAL OF HEMATOLOGY, vol.81, no.3, pp.162-170, 2006 (Journal Indexed in SCI)
2006
2006Common cytochrome p4503A (CYP3A4 and CYP3A5) and thiopurine S-methyl transferase (TPMT) polymorphisms in Turkish population
Aydin Sayitoǧlu M., Yildiz I., Hatirnaz Ö., Özbek U.
Turkish Journal of Medical Sciences, vol.36, no.1, pp.11-15, 2006 (Journal Indexed in SCI Expanded)
2006
2006Aldosterone synthase -344c/t and angiotensin-converting enzyme I/D polymorphisms in Turkish hypertensive patients with normal coronary arteries
Olcay A., Nisanci Y., Ekmekci C. G. , Umman B., Bugra Z., Sezer M., et al.
Acta Cardiologica, vol.61, no.1, pp.29-34, 2006 (Journal Indexed in SCI)
2006
2006Polymorphism of endothelial nitric oxide synthase gene in patients with erectile dysfunction
Erkan E., Muslumanoglu A. Y. , Oktar T., Sanli O., Ozbek U. , Kadioglu A.
Journal of Sexual Medicine, vol.3, no.1, pp.69-76, 2006 (Journal Indexed in SCI)
2005
2005Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries
Chan A. O. , Soliman A. S. , Zhang Q., Rashid A., Bedeir A., Houlihan P. S. , et al.
Clinical Cancer Research, vol.11, no.23, pp.8281-8287, 2005 (Journal Indexed in SCI)
2005
2005Gene expression analysis reveals a strong signature of an interferon-induced pathway in childhood lymphoblastic leukemia as well as in breast and ovarian cancer
Einav U., Tabach Y., Getz G., Yitzhaky A., Ozbek U. , Amariglio N., et al.
Oncogene, vol.24, no.42, pp.6367-6375, 2005 (Journal Indexed in SCI)
2005
2005Frequency of SOX group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters
VURAL B., Chen L., Saip P., Chen Y., Ustuner Z., Gonen M., et al.
Cancer, vol.103, no.12, pp.2575-2583, 2005 (Journal Indexed in SCI Expanded)
2005
2005Expression of IFITM1 in chronic myeloid leukemia patients
Akyerli C. , Beksac M., Holko M., Frevel M., Dalva K., Ozbek U. , et al.
Leukemia Research, vol.29, no.3, pp.283-286, 2005 (Journal Indexed in SCI)
2005
2005CYP2D6 and CYP1A1 mutations in the Turkish population
Aydin M., Hatirnaz Ö. , Erensoy N., Ozbek U.
CELL BIOCHEMISTRY AND FUNCTION, vol.23, no.2, pp.133-135, 2005 (Journal Indexed in SCI)
2005
2005The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis
Cardone M., Kandilci A., Carella C., Nilsson J., Brennan J., Sirma S., et al.
MOLECULAR AND CELLULAR BIOLOGY, vol.25, no.6, pp.2395-2405, 2005 (Journal Indexed in SCI)
2004
2004Aberrant methylation of multiple tumor suppressor genes in acute myeloid leukemia
Ekmekci C. G. , Gutiérrez M. I. , Siraj A. K. , Ozbek U. , Bhatia K.
American Journal of Hematology, vol.77, no.3, pp.233-240, 2004 (Journal Indexed in SCI)
2004
2004NAD(P)H:quinone oxidoreductase 1 null genotype is not associated with pediatric de novo acute leukemia
Sirma S., Agaoglu L., Yildiz I., Cayli D., Horgusluoglu E., Anak S., et al.
Pediatric Blood and Cancer, vol.43, no.5, pp.568-570, 2004 (Journal Indexed in SCI)
2004
2004Quantification of the FLI1 and CXCR4 gene expressions in acute lymphoblastic leukemia (ALL) patients with t(12,21)
SAVLI H., Hatirnaz Ö., Sirma S., Özdemir S., Özbek U.
Turkish Journal of Haematology, vol.21, no.2, pp.87-92, 2004 (Journal Indexed in SCI Expanded)
2004
2004Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemia t (15; 17) patients
SAVLI H., Sirma S., Nagy B., Aktan M., Dincol G., Salcioglu Z., et al.
Experimental and Molecular Medicine, vol.36, no.3, pp.279-282, 2004 (Journal Indexed in SCI)
2004
2004Expression Analysis of DEK, AF4 and FLI1 Genes in All-Trans-Retinoic Acid (ATRA) Treated Acute Promyelocytic Leukaemia t(15;17) Patients by Quantitative Real-Time PCR
SAVLI H., Sirma S., Nagy B., Aktan M., Dinçol G., Salcioǧlu Z., et al.
Turkish Journal of Medical Sciences, vol.34, no.2, pp.85-89, 2004 (Journal Indexed in SCI Expanded)
2004
2004Mutation rate at commonly used forensic STR loci: Paternity testing experience
Aşicioǧlu F., Oguz-Savran F., Ozbek U.
Disease Markers, vol.20, no.6, pp.313-315, 2004 (Journal Indexed in SCI)
2003
2003Methylenetetrahydrofolate reductase C677T polymorphism and toxicity in allogeneic hematopoietic cell transplantation [5]
Kalayoglu-Besisik S., Caliskan Y., Sargin D., Gurses N., Ozbek U.
Transplantation, vol.76, no.12, pp.1775-1777, 2003 (Journal Indexed in SCI)
2003
2003Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients
SAVLI H., Sirma S., Nagy B., Aktan M., Dincol G., Ozbek U.
Experimental and Molecular Medicine, vol.35, no.5, pp.454-459, 2003 (Journal Indexed in SCI)
2003
2003Tumour necrosis factor-alpha gene promoter region -308 and -376 G → A polymorphisms in Behçet's disease
Duymaz-Tozkir J., GÜL A., Uyar F. A. , Özbek U. , Saruhan-Direskeneli G.
Clinical and Experimental Rheumatology, vol.21, 2003 (Journal Indexed in SCI)
2003
2003Analysis of MYH Tyr165Cys and Gly382Asp variants in childhood leukemias
Akyerli C. , Ozbek U. , Aydin-Sayitoglu M., Sirma S., Ozcelik T.
Journal of Cancer Research and Clinical Oncology, vol.129, no.10, pp.604-605, 2003 (Journal Indexed in SCI)
2003
2003Quantification of all-trans-retinoic acid (ATRA) dependent expression of CXCR4 gene in acute promyelocytic leukaemia
Savli H., Sirma S., Aktan M., Dinçol G., Özbek U.
Turkish Journal of Haematology, vol.20, no.3, pp.153-159, 2003 (Journal Indexed in SCI Expanded)
2003
2003Concurrent methylation of multiple genes in childhood ALL: Correlation with phenotype and molecular subgroup
Gutierrez M., Siraj A., Bhargava M., Ozbek U. , Banavali S., Chaudhary M., et al.
Leukemia, vol.17, no.9, pp.1845-1850, 2003 (Journal Indexed in SCI)
2003
2003Expression stability of six housekeeping genes: A proposal for resistance gene quantification studies of Pseudomonas aeruginosa by real-time quantitative RT-PCR
SAVLI H., KARADENİZLİ A., KOLAYLI F., Gundes S., Ozbek U. , Vahaboglu H.
Journal of Medical Microbiology, vol.52, no.5, pp.403-408, 2003 (Journal Indexed in SCI)
2003
2003Prognostic significance of the TEL-AML1 fusion gene in pediatric acute lymphoblastic leukemia in Turkey
Ozbek U. , Sirma S., Agaoglu L., Yuksel L., Anak S., Yildiz I., et al.
Journal of Pediatric Hematology/Oncology, vol.25, no.3, pp.204-208, 2003 (Journal Indexed in SCI)
2003
2003Quantification of the FLI1 gene expression by real-time quantitative RT-PCR
SAVLI H., Sirma S., Özbek U.
Turkish Journal of Medical Sciences, vol.33, no.1, pp.21-25, 2003 (Journal Indexed in SCI Expanded)
2003
2003Molecular pathology of haemophilia B in Turkish patients: Identification of a large deletion and 33 independent point mutations
Onay U. V. , Kavakli K., KILINÇ Y., Gürgey A., Aktuǧlu G., Kemahli S., et al.
British Journal of Haematology, vol.120, no.4, pp.656-659, 2003 (Journal Indexed in SCI)
2002
2002Preclinical validation of a monochrome real-time multiplex assay for translocations in childhood acute lymphoblastic leukemia
Siraj A. K. , Ozbek U. , Sazawal S., Sirma S., Timson G., Al-Nasser A., et al.
Clinical Cancer Research, vol.8, no.12, pp.3832-3840, 2002 (Journal Indexed in SCI)
2002
2002Allele distribution data of nine short tandem repeat loci for Turkish population: D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820
Ascoglu F., Akyüz F., Çetinkaya Ü., Özbek U.
Forensic Science International, vol.129, no.1, pp.75-77, 2002 (Journal Indexed in SCI)
2002
2002Turkish population data on nine short tandem repeat loci: HumCSF1PO, HumTHO1, HumTPOX, HumFES/FPS, HumF13B, HumVWA, D3S1358, D7S820, D16S539
Aşicioglu F., Akyüz F., Çetinkaya ü., Yilmaz S., Koluaçik S., VURAL B., et al.
Forensic Science International, vol.126, no.3, pp.252-253, 2002 (Journal Indexed in SCI)
2002
2002The value of TNF-alpha and IL-10 gene polymorphisms in the incidence and severity of graft-versus-host disease
Ozbek U. , Gurses N., Kalayoglu-Besisik S., Aydin M., Bilgen H., Ongoren S., et al.
BONE MARROW TRANSPLANTATION, vol.29, 2002 (Journal Indexed in SCI)
2001
2001Genetic polymorphism of cytochrome P450 2E1 in the Turkish population
ÖMER B., Özbek U. , Akköse A., Kiliç G.
Cell Biochemistry and Function, vol.19, no.4, pp.273-275, 2001 (Journal Indexed in SCI)
2001
2001Activated protein C resistance in polycythemia vera
Günay A., Öztürk A., Budak T., Özbek U. , Üskent N.
Turkish Journal of Haematology, vol.18, no.3, pp.157-164, 2001 (Journal Indexed in SCI Expanded)
2000
2000Prognostic significance of Wilms tumor 1 gene in childhood acute lymphoblastic leukemia
Özgen Ü., Anak S., Özbek U. , Sarper N., Eryilmaz E., Aǧaoǧlu L., et al.
Turkish Journal of Haematology, vol.17, no.4, pp.183-188, 2000 (Journal Indexed in SCI Expanded)
2000
2000Detection of BCR/ABL transcripts by reverse transcriptase polimerase chain reaction in pediatric acute lymphoblastic leukemia: Incidence and clinical features
Sarper N., Özbek U. , Aǧaoǧlu L., Özgen Ü., Kandilci A., Sirma S., et al.
Turkish Journal of Haematology, vol.17, no.4, pp.197-206, 2000 (Journal Indexed in SCI Expanded)
2000
2000Is aml1/eto gene expression a good prognostic factor in pediatric acute myeloblastic leukemia?
Sarper N., Ozbek U. , Agaoglu L., Erydmaz E., Yalman N., Anak S., et al.
Pediatric Hematology and Oncology, vol.17, no.7, pp.577-583, 2000 (Journal Indexed in SCI)
2000
2000wt1 Gene expression in childhood acute leukemias
Özgen Ü., Anak S., Özbek U. , Sarper N., Eryilmaz E., Aǧaoǧlu L., et al.
Acta Haematologica, vol.103, no.4, pp.229-230, 2000 (Journal Indexed in SCI)
1999
1999Prevalence of factor V Leiden in patients with retinal vein occlusion
Demirci F. Y. K. , Güney D. B. , Akarçay K., Kir N., Özbek U. , Sirma S., et al.
Acta Ophthalmologica Scandinavica, vol.77, no.6, pp.631-633, 1999 (Journal Indexed in SCI)
1997
1997Evaluation of chimerism with DNA polymorphisms in bone marrow transplantation
Özbek U. , VURAL B., Kalayoǧlu S., Soysal T., Bilgen H., Yavuz S., et al.
Turkish Journal of Pediatrics, vol.39, no.3, pp.303-311, 1997 (Journal Indexed in SCI)
1997
1997Frequency of factor V leiden (Arg506Gln) in Turkey [2]
Ozbek U. , Tangun Y.
British Journal of Haematology, vol.97, no.2, pp.504-505, 1997 (Journal Indexed in SCI Expanded)
1997
1997Frequency of factor V Leiden (Arg506Gln) in Turkey
Ozbek U. , Tangun Y.
BRITISH JOURNAL OF HAEMATOLOGY, vol.97, no.2, pp.504-505, 1997 (Journal Indexed in SCI)
1996
1996Coagulation factor V gene mutation increases the risk of venous thrombosis in Behcet's disease
Gül A., Özbek U. , ÖZTÜRK C., Inanç M., Koniçe M., Özcelik T.
British Journal of Rheumatology, vol.35, no.11, pp.1178-1180, 1996 (Journal Indexed in SCI)
1996
1996Frequency of factor V Leiden in Turkey [1]
Ozbek U. , Tangun Y.
International Journal of Hematology, vol.64, pp.291-292, 1996 (Journal Indexed in SCI Expanded)
1996
1996Amplification in tumors and benign tissue of breast cancer patients
YAZICI H., Müslümanoǧlu M., Güzey D., Yasasever V., Özbek U. , Dalay N.
Cancer Letters, vol.107, no.2, pp.235-239, 1996 (Journal Indexed in SCI)
1996
1996Clinical and cytogenetic studies of two cases of Klinefelter syndrome with hereditary retinoblastoma and rhabdomyosarcoma
Oǧur G., Sengun Z., Arel-Kiliç G., De Busscher C., Başaran S., Ozbek U. , et al.
Cancer Genetics and Cytogenetics, vol.89, no.1, pp.77-81, 1996 (Journal Indexed in SCI)
Articles Published in Other Journals
2020
2020SCREENING SLC2A1 GENE FOR SEQUENCE AND COPY NUMBER VARIATIONS ASSOCIATED WITH GLUT-1 DEFICIENCY SYNDROME
Ornek Erguzeloglu C., KARA B., Karacan I., Ozdemir O., Kesim Y., Bebek N., et al.
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, vol.83, no.3, pp.177-183, 2020 (Journal Indexed in ESCI)
2019
2019Aberrant Methylation Profile and Microsatellit Instability in Turkish Sporadic Colorectal Carcinoma
Ekmekci C. G. , Gulluoglu M., Kapran Y., Dizdaroglu F., ÖZBEK U.
BEZMIALEM SCIENCE, vol.7, no.2, pp.86-94, 2019 (Journal Indexed in ESCI)
2018
2018Cerebral Palsy and Genetics
Akcakaya N. H. , Yapici Z., ÖZBEK U.
TURKISH JOURNAL OF NEUROLOGY, vol.24, no.1, pp.1-2, 2018 (Journal Indexed in ESCI)
2017
2017Hematolojik Maligniteler Moleküler Genetik Etiyoloji ve 2016 Dünya Sağlık Örgütü Sınıflaması
HATIRNAZ NG Ö. , ÖZBEK U.
Türkiye Klinikleri Dergisi Tıbbi Genetik Özel Sayısı, vol.2, no.2, pp.88-98, 2017 (Other Refereed National Journals)
2015
2015Does 8q24 region have potenttial risk for childhood acute lymphoblatic leukemia
HATIRNAZ NG Ö., Can İ., Fırtına S., ERBİLGİN Y., ÖZBEK U. , SAYİTOĞLU M.
DETAE, 2015 (Other Refereed National Journals)
2015
2015First Steps of the Genetic Monitorization in Primary Immune Deficiencies in the Lead of Prof. Dr. Isil Barlan in Turkey
Ng Y. Y. , Sisko S., Ng O. H. , Tatonyan S. C. , Kaya D. S. , Firtina S., et al.
TURKISH JOURNAL OF IMMUNOLOGY, vol.3, no.2, pp.47, 2015 (Journal Indexed in ESCI)
2015
20158q24 bölgesi çocukluk çağı lenfoblastik lösemiler için potansiyel risk oluşturur mu
HATIRNAZ NG Ö. , Can İ., SİNEM F., ERBİLGİN Y., ÖZBEK U. , SAYİTOĞLU M.
Deneysel Tıp Dergisi, vol.5, no.9, 2015 (Other Refereed National Journals)
2013
2013Association of MDR1 gene polymorphism in patients with temporal lobe epilepsy Temporal lob epilepsili hastalarda MDR1 gen polimorfizmi ile ilişki
ÇİNE N., Sargin G., BEBEK N., Gürses C., Baykan B., Özbek U. , et al.
Journal of Neurological Sciences, vol.30, no.1, pp.4-11, 2013 (Refereed Journals of Other Institutions)
2012
2012AKUT LÖSEMİ HÜCRE SERİLERİNDE BETA KATENİN siRNA UYGULAMALARI
HATIRNAZ NG Ö. , ERBİLGİN Y., AKTAŞ E., DENİZ G., ÖZBEK U. , SAYİTOĞLU M.
DENEYSEL TIP DERGİSİ, vol.2, no.3, pp.16-22, 2012 (Other Refereed National Journals)
2011
2011BETA KATENİN VE AXIN2 PROTEİNLERİ ETKİLEŞİMLERİNİN PROKSİMİTİ LİGASYON ASSAY YAKINSAL BAĞLANMA TESPİTİ ILE GÖRÜNTÜLENMESİ
ERBİLGİN Y., HATIRNAZ NG Ö. , SAYİTOĞLU M., SÖDERBERG O., ÖZBEK U.
DENEYSEL TIP DERGİSİ, vol.1, no.2, pp.24-27, 2011 (Other Refereed National Journals)
2005
2005CYP1A1, GSTM1 and NQO1 gene polymorphisms: Genetic risk factors for small cell lung cancer
Demirkan A., VURAL B., Üstüner Z., Uygun K., Açikalin B. Ö. , Derin D., et al.
Turkish Journal of Cancer, vol.35, no.4, pp.171-176, 2005 (Refereed Journals of Other Institutions)
Refereed Congress / Symposium Publications in Proceedings
2017
2017Primer Antikor Yetersizliği Olan Hastalarda Saptanan Bruton Tirozin Kinaz (BTK) Gen Varyasyonları
Firtina S., NG Y. Y. , HATIRNAZ NG Ö. , HASKOLOĞLU Z. Ş. , Kıykım A., AYDINER E., et al.
24. Ulusal İmmünoloji Kongresi, Turkey, 27 April 2017 - 30 April 2027
2020
2020Biallelic NALCN variant detected by homozygosity mapping and whole exome sequencing in a consanguineous family from Turkey
Süsgün S., Yücesan E., Çalık M., Özbek U. , Uğur İşeri S. A.
European Society of Human Genetics Annual Meeting 2020, Berlin, Germany, 6 - 09 June 2020, pp.1
2019
2019Screening TYR gene variations in Turkish oculocutaneuse albinism patients
Hatırnaz Ng Ö. , Özbek U. , Alanay Y. , Yararbaş K.
Avrupa Insan Genetiği Derneği Kongresi, Gothenburg, Sweden, 15 - 19 June 2019, vol.27, pp.1233-1234
2019
2019Screening TYR gene variations in Turkish oculocutaneuse albinism patients
Ng O. H. , YILMAZ E. , Parlakgunes Z., YARARBAŞ K. , Ziylan S., ALANAY Y. , et al.
52nd Conference of the European-Society-of-Human-Genetics (ESHG), Gothenburg, Sweden, 15 - 18 June 2019, vol.27, pp.1233-1234
2018
2018Identification of the post-zygotic mosaic nonsense mutation in WDR45gene leading to beta-propeller protein-associated neurodegeneration and defining sex chromosomal mosaicism at whole exome sequencing
Akcakaya N. H. , Salman B., Arguden Y. T. , Gormez Z., Donmez R., Colakoglu B., et al.
51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), Milan, Italy, 16 - 19 June 2018, vol.27, pp.535-536
2017
2017IKZF1 Deletions at Diagnose and Relapse of Childhood B-ALL
Erbilgin Y., Firtina S., Ng O. H. , Celkan T., Karakas Z., Anak S. S. , et al.
59th Annual Meeting of the American-Society-of-Hematology (ASH), Georgia, United States Of America, 9 - 12 December 2017, vol.130
2017
2017Çocukluk Çağı B-ALL Hastalarinda IKZF1 Delesyonlarinin Araştırılması
ERBİLGİN Y., HATIRNAZ NG Ö. , SAYİTOĞLU M., ÖZBEK U.
43. Ulusal Hematoloji Kongresi, Turkey, 1 - 04 November 2017
2017
2017SKF82958’xxİN SIÇANLARDA NALOKSON İLE BAŞLATILAN MORFİN YOKSUNLUK SENDROMU BELİRTİLERİ VE HİPOKAMPAL DOKU PLAZMİNOJEN AKTİVATÖRÜ mRNA DÜZEYLERİ ÜZERİNE ETKİLERİ
Aslan A., HATIRNAZ NG Ö. , Taşar O., ÖZBEK U. , YAMANTÜRK ÇELİK A. P.
24. Ulusal Farmakolji kongresi, Turkey, 17 - 22 October 2017
2017
2017SKF82958’xxin sıçanlarda nalokson ile başlatılan morfin yoksunluk sendromu belirtileri ve hipokampal doku plazminojen aktivatörü mRNA düzeyleri üzerine etkileri
ASLAN A., HATIRNAZ NG Ö. , TAŞAR O., ÖZBEK U. , YAMANTÜRK ÇELİK A. P.
24. Ulusal Farmakoloji Kongresi, Trabzon, Turkey, 17 - 20 October 2017
2017
2017Effects of enriched environment and memantine on naloxone precipitated morphine-abstinence syndrome in rats
ASLAN A., HATIRNAZ NG Ö. , TAŞAR O., ÖZBEK U. , YAMANTÜRK ÇELİK A. P.
6th Meeting of the International Drug Abuse Research Society, Dubrovnik, Croatia, 4 - 08 September 2017
2017
2017Research Biobank for Leukemia
ERBİLGİN Y., HATIRNAZ NG Ö. , Fırtına S., Khodzaev K., ÖZBEK U. , SAYİTOĞLU M., et al.
Towards Harmonyin Biobanking, Switzerland, 01 June 2017 - 03 June 2107
2017
2017PTEN AND AKT1 GENE VARIATIONS IN CHILDHOODT-ALL PATIENTS
Küçükcankurt F., HATIRNAZ NG Ö. , ERBİLGİN Y., ÖZBEK U. , KARAKAŞ Z., CELKAN T. T. , et al.
6th International Congress onLeukemia – Lymphoma – Myeloma, 11 - 13 May 2017
2017
2017Primer Antikor Yetersizliği Olan Hastalarda Saptanan Bruton Kinaz (BTK) Gen Varyasyonları
Fırtına S., Yin Y., HATIRNAZ NG Ö. , HASKOLOĞLU Z. Ş. , Kıykım A., AYDINER E., et al.
24.Ulusal İmmünoloji Kongresi, Turkey, 27 - 30 April 2017
2017
2017Ağır Kombine İmmün Yetmezlik Hastalarında TREC/KREC Analizleri ve Klnik Uyumunun Araştırılması
NG Y. Y. , Firtina S., HATIRNAZ NG Ö. , Nepesov S., Kıykım A., AYDINER E., et al.
3. Klinik İmmünoloji Kongresi, Turkey, 12 - 15 April 2017
2017
2017Primer Antikor Yetmezlik Hastalarında Hastalığa Sebep Olan Varyantların Yen Nesil Genetik Tanı Paneli ile Tespiti
Firtina S., NG Y. Y. , HATIRNAZ NG Ö. , CAMCIOĞLU Y., AYDINER E., Kara M., et al.
3. Klinik İmmünoloji Kongresi, Turkey, 12 - 15 April 2017
2016
2016Real-Life Data and a Single Center Experience on the Efficacy and Toxicity Profile of Imatinib in the Treatment of Elderly Patients with Chronic Myeloid Leukemia
Eskazan A. E. , Oztas M., Bektas F., Sadri S., Keskin D., Yurttas N. O. , et al.
58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), California, United States Of America, 3 - 06 December 2016, vol.128
2016
2016Turkish National Severe Congenital Neutropenia Registry
Karapinar D. Y. , Karakas Z., PATIROĞLU T., Metin A., Caliskan U., Celkan T., et al.
58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), California, United States Of America, 3 - 06 December 2016, vol.128
2016
2016Primer İmmün Yetersizliklerde Hastalıkla İlişkili Aday Varyantların Tespiti
Fırtına S., NG Y. Y. , HATIRNAZ NG Ö. , CAMCIOĞLU Y., AYDINER E., Kaya A., et al.
12.Ulusal Tıbbi Genetik kongresi, Turkey, 5 - 09 October 2016
2016
2016Prognostic Significance of IKZF1 Deletions in Childhood B ALL
ERBİLGİN Y., Fırtına S., HATIRNAZ NG Ö. , KARAKAŞ Z., CELKAN T. T. , SARPER N., et al.
27th Annual Meeting of the International BFM Study Group, 23 - 26 April 2016
2015
2015Pathways associated with relapse and high risk in childhood acute lymphoblastic leukemia
ERBİLGİN Y., HATIRNAZ NG Ö., İşlek B., Fırtına S., CELKAN T. T. , ANAK S. S. , et al.
Europian Human Genetics Conference 2015, 6 - 09 June 2015
2015
201577 new CNV regions identified in ITP provide evidence for genetic predisposition
AR M. C. , Yücesan E., YALNIZ F. F. , HATIRNAZ NG Ö., Salihoğlu A., BERK S., et al.
57th Annual Meeting & Exposition, 5 - 08 December 2015
2015
2015Down regulation of SnoN SKIL gene in T cel acute lymphoblastic leukemia
HATIRNAZ NG Ö., Taşar O., NG Y. Y. , Öztunç C., ERBİLGİN Y., SAYİTOĞLU M., et al.
Europian Human GeneticsConference 2015, 6 - 09 June 2015
2015
2015hRgr overexpretion in human T cell malignancy
Burak İ., KARAKAŞ Z., SOYSAL T., SAYİTOĞLU M., Süzme R., ÖZBEK U.
Europian Human GeneticsConference 2015, 6 - 09 June 2015
2015
2015New CNV Regions Identified in ITP Provide Evidence for Genetic Predisposition
Ar M. C. , Yucesan E., Yalniz F., Ng O. H. , Salihoglu A., Berk S., et al.
57th Annual Meeting of the American-Society-of-Hematology, Florida, United States Of America, 5 - 08 December 2015, vol.126
2015
2015Pediatrik T ALL hastalarında regulatör mikroRNA ların yolak analizleri ile belirlenmesi
Khodzhaev K., HATIRNAZ NG Ö. , ERBİLGİN Y., ÖZBEK U. , SAYİTOĞLU M.
14. Tıbbi Biyoloji ve Genetik Kongresi, Turkey, 27 - 30 October 2015
2015
2015T Hücreli Akut Lenfoblastik Lösemi Hücre Hatlarında SKIL geni ve hsa miR 223 Fonksiyonel İlişkisi
HATIRNAZ NG Ö. , ORÇUN T., NG Y. Y. , CEREN Ö., ÖZBEK U. , SAYİTOĞLU M.
41. ULUSAL HEMATOLOJİ KONGRESİ, Turkey, 21 - 24 October 2015
2015
2015KML monitorizasyonunda yeni bir kantitatif analiz raporlama ve takip yazılımı REPTILE
HATIRNAZ NG Ö. , ÖZDEMİR Ö., SAYİTOĞLU M., ÖZBEK U.
41. ULUSAL HEMATOLOJİ KONGRESİ, Turkey, 21 - 24 October 2015
2015
2015GENERIC IMATINIB IN NEWLY DIAGNOSED CHRONIC MYELOID LEUKEMIA (CML) PATIENTS IN CHRONIC PHASE: UPDATED DATA FROM A TURKISH CML COHORT
Eskazan A. E. , Ayer M., Kantarcioglu B., Demirel N., Aydin D., Aydinli F., et al.
20th Congress of European-Hematology-Association, Vienna, Austria, 11 - 14 June 2015, vol.100, pp.447-448
2015
2015THIRD-LINE TREATMENT WITH 2ND GENERATION TYROSINE KINASE INHIBITORS (TKIS) IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA WHO FAILED TWO PRIOR TKIS: A SINGLE CENTER EXPERIENCE OF 21 PATIENTS
Salihoglu A., Eskazan A. E. , Suzan V., Savci S., Erdogan I., Berk S., et al.
20th Congress of European-Hematology-Association, Vienna, Austria, 11 - 14 June 2015, vol.100, pp.696-697
2015
2015THE EFFICACY AND SAFETY OF GENERIC IMATINIB IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA (CML) AFTER SWITCHING FROM GLIVEC: UPDATED DATA FROM CERRAHPASA CML COHORT
Soysal T., Eskazan A. E. , Sadri S., Erdogan I., Berk S., Yalniz F. F. , et al.
20th Congress of European-Hematology-Association, Vienna, Austria, 11 - 14 June 2015, vol.100, pp.447
2015
2015OUTCOMES OF CHRONIC PHASE CHRONIC MYELOID LEUKEMIA PATIENTS WITH 10%<= AND > 10% BCR-ABL1 (IS) TRANSCRIPT LEVELS AFTER 3 MONTHS OF GENERIC IMATINIB TREATMENT
Baslar Z., Eskazan A. E. , Ayer M., Kantarcioglu B., Demirel N., Aydin D., et al.
20th Congress of European-Hematology-Association, Vienna, Austria, 11 - 14 June 2015, vol.100, pp.439-440
2015
2015INTERNATIONAL CONTROL ROUND FOR DEEP SEQUENCING ANALYSIS OF BCR-ABL KINASE DOMAIN MUTATIONS IN 11 LABORATORIES FROM 7 EUROPEAN COUNTRIES
Ernst T., Rinke J., Stiens M., Soverini S., De Benedittis C., Polakova K. M. , et al.
20th Congress of European-Hematology-Association, Vienna, Austria, 11 - 14 June 2015, vol.100, pp.326
2015
2015NILOTINIB RESULTS IN IMPROVED RATES OF MOLECULAR RESPONSE IN TURKISH NEWLY DIAGNOSED CML-CP PATIENTS: A 24-MONTH UPDATE
SAYDAM G., HAZNEDAROĞLU İ. C. , KAYNAR L., Yavuz A., Ali R., GÜVENÇ B., et al.
20th Congress of European-Hematology-Association, Vienna, Austria, 11 - 14 June 2015, vol.100, pp.695-696
2015
2015PEDIATRIC TEL-AML1-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS SHOW INCREASED MN1 EXPRESSION
Yener M. D. , Numata M., Ekmekci S. S. , Aydın M., Grosveld G., Ozbek U. , et al.
20th Congress of European-Hematology-Association, Vienna, Austria, 11 - 14 June 2015, vol.100, pp.633
2015
2015Down regulation of SnoN SKIL gene in T cell acute lymphoblastic leukemia
HATIRNAZ NG Ö. , Taşar O., NG Y. Y. , CEREN Ö., ERBİLGİN Y., SAYİTOĞLU M., et al.
5th International Congress of Leukemia Lymphoma Myeloma, 21 - 23 May 2015
2014
2014Correlation between phenotypic and genotypic tetracycline resistance of Escherichia coli isolates from food of animal origin
MURATOĞLU K., Özdemir Ö., Eker F., Bayrakal M., Levent G., UĞUR İŞERİ S. A. , et al.
European Biotechnology Congress, 15 - 18 May 2014, vol.185, pp.85
2012
2012Expression Levels of Local RAS in Lymphoid and Myelid Malignancies
Çatal Tatonyn S., UZ B., SAYİTOĞLU M., ERBİLGİN Y., HATIRNAZ NG Ö. , ÖZBEK U. , et al.
ELN Frontiers Meeting, 09 November 2012
2011
2011T HÜCRELİ AKUT LENFOBLASTİK LÖSEMİDE GENOM BOYU ANLATIM ANALİZLERİ
HATIRNAZ NG Ö. , SAYİTOĞLU M., ERBİLGİN Y., ÖZTUNÇ C., STAAL F., VAN DONGEN J., et al.
3. DETAE GÜNLERİ, Turkey, 17 - 18 November 2011
2011
2011A new noncoding risk factor for Acute Lymphoblastic Leukemia 8q24 region preliminary data
Can İ., HATIRNAZ NG Ö. , ERBİLGİN Y., Öztunç C., SAYİTOĞLU M., ÖZBEK U.
The 3.rd EMBO meeting, 10 - 13 September 2011
2010
2010Mutations in Axin1 APC and Beta catenin Genes in T cell Acute Lymphoblastic Leukemia
SAYİTOĞLU M., ERBİLGİN Y., HATIRNAZ NG Ö. , ÖZBEK U.
European School of Hematology, Scientific Workshop T-cell Acute Lymphoblastic Leukemia (T-ALL) Meets Normal T-cell Development, 7 - 09 May 2010
2009
2009Expression Analysis of Some Candidate Genes Involved in Neurotransmission and Neurogenesis in Human Hippocampal Sclerosis
BEBEK N., SAYİTOĞLU M., özdemir ö., Baykan B., ÖZBEK U. , Karasu A., et al.
American Academy of Neurology 63nd Annual Meeting, 4 - 08 December 2009
2009
2009AKUT LÖSEMİLERDE ANORMAL WNT SİNYAL İLETİ YOLU AKTİVASYONU
SAYİTOĞLU M., HATIRNAZ NG Ö. , ERBİLGİN Y., SİNEM Ö., AKTAŞ ÇETİN E., MAVİ N., et al.
1. DETAE GÜNLERİ, Turkey, 15 - 16 November 2009
2009
2009Pax5 Expression Levels are increased in B Cell acute lymphoblastic leukemia patients
Fırtına S., SAYİTOĞLU M., ERBİLGİN Y., Mavi N., HATIRNAZ NG Ö. , ÖZBEK U.
MediMedGen Meeting, 28 June - 01 July 2009
2009
2009Mutation Analysis of c ABL Gene in Imatinib Resistant Chronic Myeloid Leukemia Patients
ERBİLGİN Y., Çatal S., HATIRNAZ NG Ö. , SAYİTOĞLU M., SOYSAL T., ÖZBEK U.
MediMedGen Meeting, 28 June - 01 July 2009
2009
2009Mutations in Axin 1 APC and B catenin Genes in Acute Lymphoblastic Leukemia
SAYİTOĞLU M., ERBİLGİN Y., HATIRNAZ NG Ö. , Rourke E., ÖZBEK U.
MediMedGen Meeting, 28 June - 01 July 2009
2008
2008T ALL HASTALARINDA NOTCH1 MUTASYONUNUN ARAŞTIRILMASI
ERBİLGİN Y., SAYİTOĞLU M., HATIRNAZ Ö. , YÜKSEL L., İNCİ Y., AĞAOĞLU L., et al.
34. ULUSAL HEMATOLOJİ KONGRESİ, Turkey, 8 - 11 November 2008
2008
2008EPIGENETIC INACTIVATION OF WNT5A BY PROMOTER METHYLATION IN ACUTE LEUKEMIA PATIENTS
ERBİLGİN Y., SAYİTOĞLU M., HATIRNAZ Ö. , ÖZBEK U.
EMBO WORKSHOP ON GENOMIC IMPRINTING, 21 - 24 September 2008
2008
2008T HÜCRELİ AKUT LENFOBLASTİK LÖSEMİ GELİŞİMİNDE ROL OYNAYAN ONKOGENİK YAZILIM FAKTÖRLERİNİN EKSPRESYONLARININ ARAŞTIRILMASI
SAYİTOĞLU M., ERBİLGİN Y., HATIRNAZ Ö. , ÖZBEK U.
8. ULUSAL TIBBİ GENETİK KONGRESİ, Turkey, 6 - 09 May 2008
2007
2007AKUT LÖSEMİ HASTALARINDA WNT SİNYAL İLETİ YOLU GENLERİNİN HİPERMETİLASYON ANALİZLERİ
HATIRNAZ Ö. , SAYİTOĞLU M., ÖZBEK U.
33. ULUSAL HEMATOLOJİ KONGRESİ, Turkey, 16 - 19 November 2007
2006
2006Detection of SOCS 1 suppressor of cytokine signaling 1 methylation in CML chronic myeloid leukemia patients
HATIRNAZ Ö. , Ekmekçi C., AR M. C. , ÜRE Ü. B. , SOYSAL T., FERHANOĞLU A. B. , et al.
31st FEBS Congress, 24 - 29 June 2006, vol.273
2006
2006KRONİK MYELOİD LÖSEMİ GELİİMİNDE SOCS1 GEN METİLLENMESİN
HATIRNAZ Ö. , EKMEKÇİ C. G. , ÜRE Ü. B. , FERHANOĞLU A. B. , SOYSAL T., ÖZÇELİK H. T. , et al.
7. ULUSAL PRENATAL TANI VE TIBBİ GENETİK KONGRESİ, Turkey, 17 - 20 May 2006
2003
2003DETOKSİFİKASYON ENZİM GEN POLİMORFİZİMLERİNİN AKUT LÖSEMİ ETİYOLOJİSİNDEKİ ROLLERİ
SAYİTOĞLU M., HATIRNAZ Ö. , ÖZBEK U.
30. ULUSAL HEMATOLOJİ KONGRESİ, Turkey, 10 - 14 November 2003
2003
2003ALLELOTYPEFREQUENCIES OF TPMT CYP3A4 AND CYP23A5 GENES IN TURKISH POPULATION
ÖZBEK U. , SAYİTOĞLU M., HATIRNAZ Ö.
5th INTERNATIONAL SYMPOSIUM ON LEUKEMIA AND LYMPHOMA, 12 May - 15 March 2003
2001
2001Metabolising enzyme polymorphisms GSTM1 GSTT1 CYP1A1 CYP2D6 and their association as a potential susceptibility to pediatric ALL
ÖZBEK U. , SAYİTOĞLU M., HATIRNAZ NG Ö. , Ağaoğlu L., SIRMA EKMEKCİ S., Yüksel L., et al.
43rd American Society of Hematology Meeting, 7 - 11 December 2001
Books & Book Chapters
2019
2019Basic Concepts in Genetics
Erbilgin Y., Özbek U.
in: Cerebral Palsy and Genetics, Hande Akçakaya,Uğur Özbek, Editor, Boyut Yayın Grubu, İstanbul, pp.11-26, 2019
Supported Projects
2019 - 2027
2019 - 2027Sağlık Alanında İleri Analiz Teknikleri ve Hücresel Tedaviler Geliştirilmesi için Ulusal Yetkinliğin Arttırılması
TUBITAK Project
Özbek U. (Executive)
2019 - 2023
2019 - 2023European Research Program on Rare Diseases
H2020 Project
(Project Abstract)
Özbek U. , Alanay Y. , Sezerman O. U. , Julkowska D.(Executive)
2018 - 2022
2018 - 2022LEukaemia GENe Discovery by data sharing, mining and collaboration
TÜBİTAK - AB COST Project
Hatırnaz Ng Ö. , Özbek U. (Executive)
2020 - 2021
2020 - 2021TÜSEB Bireysel ve Dönüşümsel Tıp Alanındaki Uygulamalı Proje Çağrısı: Akut lenfoblastik lösemi
Ministry of Health
Hatırnaz Ng Ö. , Sayitoğlu M., Özbek U. , Çine N., Canpolat C.
2020 - 2021
2020 - 2021Albinizm Hastalıklarında gen varyantlarının ekzom analizi ile belirlenmesi
Project Supported by Higher Education Institutions
Hatırnaz Ng Ö. (Executive) , Özbek U. , Alanay Y.
2019 - 2021
2019 - 2021Bireysel ve Dönüşümsel Tıp Alanındaki Uygulamalı Proje Çağrısı: Albinizm
Turkey Institutes of Health Administration Project
Hatırnaz Ng Ö. , Özbek U. (Executive) , Alanay Y.
2019 - 2020
2019 - 2020İSTisNA- İStanbul Tanısız ve NAdir Hastalıklara Çözüm Platformu Fizibilite Projesi
Development Agency
Hatırnaz Ng Ö. , Özbek U. (Executive) , Şahin A. , Alanay Y.
2019 - 2020
2019 - 2020Genetic predisposition to leukemia and lymphoma
Project Supported by Higher Education Institutions
Özbek U. (Executive) , Hatırnaz Ng Ö. , Alanay Y.
Memberships / Tasks in Scientific Organizations
2019 - Continues
2019 - ContinuesIBFM’s Genetic Variation Committee
Member of Science Committee
2019 - Continues
2019 - ContinuesSIOPE Host Genome Working Group
Member of Science Committee
2017 - Continues
2017 - ContinuesTÜSEB, Türkiye Halk Sağlığı ve Kronik Hastalıklar Enstitüsü
Member of Science Committee
2017 - Continues
2017 - ContinuesTürkiye Spastik Çocuklar Vakfı
Member of Science Committee
Scientific Refereeing
September 2020
September 2020H2020 Project
FET, H2020 Future & Emerging Technologies Project, IZMİR BİOMEDİCİNE AND GENOME CENTER, Turkey
June 2020
June 2020TUBITAK Project
1002 - Quick Support Program, Biruni University, Turkey
May 2020
May 2020Project Supported by Other Official Institutions
Sivas Cumhuriyet University, Turkey
March 2020
March 2020Project Supported by Higher Education Institutions
BAP Research Project, Istanbul Arel University, Turkey
February 2020
February 2020TUBITAK Project
1501 - Industry R & D Projects Support Program, SenteBiolab, Turkey
October 2019
October 2019Project Supported by Other Official Institutions
Hacettepe University, Turkey
October 2019
October 2019Project Supported by Other Official Institutions
Hacettepe University, Turkey
October 2019
October 2019H2020 Project
FET, H2020 Future & Emerging Technologies Project, Hacettepe University, Turkey
October 2019
October 2019H2020 Project
FET, H2020 Future & Emerging Technologies Project, Hacettepe University, Turkey
September 2019
September 2019H2020 Project
FET, H2020 Future & Emerging Technologies Project, IZMİR BİOMEDİCİNE AND GENOME CENTER, Turkey
Tasks In Event Organizations
Mart 2020
Mart 20202020 Nadir Hastalıklar Günü
Workshop Organization
Hatırnaz Ng Ö. , Özbek U. , Alanay Y.
İstanbul, Turkey
Şubat 2020
Şubat 2020İSTiSNA Projesi Paydaş Ağı Çalıştayı
Workshop Organization
Hatırnaz Ng Ö. , Özbek U. , Alanay Y.
İstanbul, Turkey
Ekim 2019
Ekim 2019HIGHLIGHTS OF BERTINORO Predisposition to leukemia and lymphoma
Workshop Organization
Hatırnaz Ng Ö. , Özbek U.
İstanbul, Turkey
Mayıs 2019
Mayıs 2019Clinical Genomics and NGS Hybrid Course
Scientific Congress
Akyerli Boylu C. , Özbek U. , Hatırnaz Ng Ö. , Alanay Y. , Ağırbaşlı D. , Öz Arslan D.
İstanbul, Turkey
Mart 2019
Mart 2019Predisposition to hereditary leukemia and lymphoma training school
Workshop Organization
Özbek U.
Bologna, Italy
Edit Congress and Symposium Activities
2020
202056. Ulusal Online Nöroloji Kongresi
Session Moderator
Antalya-Turkey
2020
202014. Ulusal Tıbbi Genetik Kongresi
Session Moderator
Ankara-Turkey
2020
20204th International Istanbul Breast Cancer Virtual Conference-Breastanbul 2020”.
Moderator
İstanbul-Turkey
2020
20203. GençOMÜ Kongresi
Invited Speaker
Çanakkale-Turkey
2020
2020Biruni Nadir Hastalıklar Günü
Invited Speaker
İstanbul-Turkey
2020
2020Tıbbi Onkoloji Derneği Mezuniyet Sonrası Güncelleme Kursu
Panelists
İstanbul-Turkey
2020
2020Pediaric Leukemia Lymphoma Predisposition Course
Invited Speaker
Ankara-Turkey
2019
201945. Ulusal Hematoloji Kongresi
Session Moderator
Antalya-Turkey
2019
2019Bulgarian Rare Disease Congress
Invited Speaker
Plovdiv-Bulgaria
2019
20195. Nadir Nörolojik Hastalıklar Sempozyumu
Session Moderator
İstanbul-Turkey
2019
20194th International EMU Genetics Club Science Symposium
Invited Speaker
Girne-Cyprus (Kktc)
2019
2019Ulusal Kanser Kongresi
Invited Speaker
Antalya-Turkey
2019
2019Balkan Genetics Congress
Invited Speaker
Edirne-Turkey
2019
2019AGÜ 4. yaşam bileimleri kongresi
Invited Speaker
Kayseri-Turkey
2019
2019ACUGEN 2. yaşam bilimleri kongresi
Session Moderator
İstanbul-Turkey
2019
2019Erciyes Genetik Günleri
Working Group
Kayseri-Turkey
2019
20196. Ulusal Hastane ve Kurum Eczacıları Kongresi
Working Group
Antalya-Turkey
Invited Talks
September 2019
September 2019Türkiyede Nadir Hastalıklar
Conference
Çocuk Genetik Derneği-Turkey
July 2019
July 2019Türkiyede Nadir Hastalıklar
Workshop
TBMM Nadir Hastalıklar Komisyonu-Turkey
April 2019
April 2019Hemophilia Genetics
Conference
Yakın Doğu Üniversitesi-Cyprus (Kktc)
Citations
Total Citations (WOS): 2306
h-index (WOS): 26
Jury Memberships
May-2020
May 2020Appointment Academic Staff
Appointment Academic Staff - Biruni Üniversitesi
February-2020
February 2020Appointment Academic Staff
Appointment Academic Staff - Ondokuz Mayıs Üniversitesi
December-2019
December 2019Doctoral Examination
Doctoral Examination - İstanbul Üniversitesi
December-2019
December 2019Appointment Academic Staff
Appointment Academic Staff - Alanya Alaaddin Keykubat Üniversitesi
December-2019
December 2019Doctoral Examination
Doctoral Examination - İstanbul Üniversitesi
November-2019
November 2019Appointment Academic Staff
Appointment Academic Staff - Sanko Üniversitesi
August-2019
August 2019Appointment Academic Staff
Appointment Academic Staff - Biruni Üniversitesi
April-2019
April 2019Doctorate
Doctorate - İstanbul Üniversitesi
February-2019
February 2019