The role of mediastinal adipose tissue 11β-hydroxysteroid d ehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease


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Atalar F., Gormez S., Caynak B., Akan G., Tanriverdi G., Bilgic-Gazioglu S., ...Daha Fazla

Cardiovascular Diabetology, cilt.11, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1186/1475-2840-11-115
  • Dergi Adı: Cardiovascular Diabetology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Mediastinal adipose tissue, Glucocorticoid, Inflammation, Coronary artery disease, Stearidonic acid, Cortisol, ECHOCARDIOGRAPHIC EPICARDIAL FAT, DEHYDROGENASE TYPE-1, METABOLIC SYNDROME, CARDIOMETABOLIC RISK, VISCERAL OBESITY, PERICARDIAL FAT, INSULIN-RESISTANCE, MESSENGER-RNA, INFLAMMATION, CORTISOL
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: Visceral fat deposition and its associated atherogenic complications are mediated by glucocorticoids. Cardiac visceral fat comprises mediastinal adipose tissue (MAT) and epicardial adipose tissue (EAT), and MAT is a potential biomarker of risk for obese patients.