PTEN and AKT1 Variations in Childhood T-Cell Acute Lymphoblastic Leukemia


Kucukcankurt F., Erbilgin Y., Firtina S., Hatirnaz Ö. , Karakas Z., Celkan T., ...More

TURKISH JOURNAL OF HEMATOLOGY, vol.37, no.2, pp.98-103, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.4274/tjh.galenos.2019.2019.0282
  • Title of Journal : TURKISH JOURNAL OF HEMATOLOGY
  • Page Numbers: pp.98-103

Abstract

Objective: PTEN/AKT pathway deregulations have been reported to be associated with treatment response in acute leukemia. This study examined pediatric T-cell acute lymphoblastic leukemia (T-ALL) samples for PTEN and AKT1 gene variations and evaluated the clinical findings.