PTEN and AKT1 Variations in Childhood T-Cell Acute Lymphoblastic Leukemia


Kucukcankurt F., Erbilgin Y., Firtina S., Hatirnaz Ö. , Karakas Z., Celkan T., et al.

TURKISH JOURNAL OF HEMATOLOGY, cilt.37, ss.98-103, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Objective: PTEN/AKT pathway deregulations have been reported to be associated with treatment response in acute leukemia. This study examined pediatric T-cell acute lymphoblastic leukemia (T-ALL) samples for PTEN and AKT1 gene variations and evaluated the clinical findings.