Prof. Dr. MELTEM MÜFTÜOĞLU

Yayın Ağı

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler 37

1. Preparation and Characterization of Hydrophobin 4-Coated Liposomes for Doxorubicin Delivery to Cancer Cells.

Osmanagaoglu F. H., Ekmekcioglu A., Ozcan B., Bayram Akcapinar G., Muftuoglu M.

Pharmaceuticals (Basel, Switzerland) , cilt.17, sa.11, 2024 (SCI-Expanded)

2. Mitochondria-Targeted Liposomes for Drug Delivery to Tumor Mitochondria

Ekmekçioğlu A., Gök Özatay Ö., Öz Arslan D., Erdal M. S., Uzuner Y., Müftüoğlu M.

PHARMACEUTICS , cilt.16, sa.7, ss.950-968, 2024 (SCI-Expanded)

3. Cosmic Whirl: Navigating the Comet Trail in DNA: H2AX Phosphorylation and the Enigma of Uncertain Significance Variants.

Ustun Yilmaz S., Agaoglu N. B., Manto K., Muftuoglu M., Özbek U.

Genes , cilt.15, sa.6, 2024 (SCI-Expanded)

4. Formulation development and evaluation of fluvastatin loaded transethosomes: Characterization, stability, in vitro dermal penetration, cytotoxicity and antipsoriatic activity studies

Yurtsever A. G., Ekmekcioglu A., Müftüoğlu M., Güngör S., Erdal M. S.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY , cilt.91, ss.1-13, 2023 (SCI-Expanded)

5. Association of mtDNA Copy Number Variations with Neoadjuvant in Triple Negative Breast Cancer Patients

Manto K., Yilmaz S. U., PALA KARA Z., URAS C., TOKAT F., İNCE Ü., et al.

BREAST , 2023 (SCI-Expanded)

6. P050 Functional characterization of genomic variants of uncertain significance (VUS) in the ATM gene

Yilmaz S. U., Manto K., Ozdemir O., Agaoglu N., Ng O. H., Müftüoğlu M., et al.

BREAST , cilt.68, ss.534-535, 2023 (SCI-Expanded)

7. Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth

Somuncu B., Ekmekcioglu A., Antmen F. M., Ertuzun T., Deniz E., Keskin N., et al.

PLOS ONE , cilt.17, sa.6 June, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

8. Leukocyte telomere length as a compensatory mechanism in vitamin D metabolism

AĞIRBAŞLI D., Kalyoncu M., MÜFTÜOĞLU M., Aksungar F., Agirbasli M.

PLOS ONE , cilt.17, sa.2, 2022 (SCI-Expanded)

9. Parents of ataxia-telangiectasia patients display a distinct cellular immune phenotype mimickingATM-mutated patients

Öğülür İ., Ertuzun T., Kocamış B., Kendir Demirkol Y., Uyar E., Kıykım A., et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY , cilt.32, sa.2, ss.349-357, 2021 (SCI-Expanded)

10. Non-muscle invasive bladder cancer tissues have increased base excision repair capacity

Somuncu B., Keskin S., Antmen F., Saglican Y., Ekmekcioglu A., Ertuzun T., et al.

SCIENTIFIC REPORTS , cilt.10, sa.1, 2020 (SCI-Expanded)

11. Investigation of base excision repair gene variants in late-onset Alzheimer's disease.

Ertuzun T., Semerci A., Cakir M. E., Ekmekçioğlu A., Gok M. O., Soltys D. T., et al.

PloS one , cilt.14, 2019 (SCI-Expanded)

12. Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency.

Gul E., Sayar E., Gungor B., Eroglu F., Surucu N., Keles S., et al.

The Journal of allergy and clinical immunology , cilt.142, ss.246-257, 2018 (SCI-Expanded)

13. Formation and repair of oxidative damage in the mitochondrial DNA

Müftüoğlu M., Mori M. P., De Souza-Pinto N. C.

MITOCHONDRION , cilt.17, ss.164-181, 2014 (SCI-Expanded)

14. Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity

Aamann M. D., Hvitby C., Popuri V., Muftuoglu M., Lemminger L., Skeby C. K., et al.

MECHANISMS OF AGEING AND DEVELOPMENT , cilt.135, ss.1-14, 2014 (SCI-Expanded)

15. PHARMACOLOGIC INHIBITION OF C-JUN N-TERMINAL KINASE (JNK) SIGNALING PATHWAY INHIBITS PROLIFERATION, BLOCKS CELL CYCLE PROGRESSION AND INDUCES APOPTOSIS OF HUMAN GRANULOSA CELL TUMOR

Oktem O., Taskiran C., MÜFTÜOĞLU M., Ata B., Senbabaoglu F., ARVAS M. B., et al.

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER , sa.8, 2013 (SCI-Expanded)

16. Multiple interaction partners for Cockayne syndrome proteins: Implications for genome and transcriptome maintenance

Aamann M. D., Muftuoglu M., Bohr V. A., Stevnsner T.

MECHANISMS OF AGEING AND DEVELOPMENT , cilt.134, ss.212-224, 2013 (SCI-Expanded)

17. Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane

Aamann M. D., Sorensen M. M., Hvitby C., Berquist B. R., Muftuoglu M., Tian J., et al.

FASEB JOURNAL , cilt.24, sa.7, ss.2334-2346, 2010 (SCI-Expanded) Sürdürülebilir Kalkınma

18. The Recombination Protein RAD52 Cooperates with the Excision Repair Protein OGG1 for the Repair of Oxidative Lesions in Mammalian Cells

de Souza-Pinto N. C., Maynard S., Hashiguchi K., Hu J., Muftuoglu M., Bohr V. A.

MOLECULAR AND CELLULAR BIOLOGY , cilt.29, sa.16, ss.4441-4454, 2009 (SCI-Expanded) Sürdürülebilir Kalkınma

19. Cockayne Syndrome Group B Protein Stimulates Repair of Formamidopyrimidines by NEIL1 DNA Glycosylase

MÜFTÜOĞLU M., de Souza-Pinto N. C., Dogan A., Aamann M., Stevnsner T., Rybanska I., et al.

JOURNAL OF BIOLOGICAL CHEMISTRY , cilt.284, sa.14, ss.9270-9279, 2009 (SCI-Expanded)

20. Mitochondrial Respiratory Chain Enzyme Activities, mtDNA Variants and Gene Expression Levels in Idiopathic Parkinson's Disease

ERCAN A., Kulaksiz G., Dalmizrak O., Muftuoglu M., Ogus H., Cavdar L., et al.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.34, sa.2, ss.97-104, 2009 (SCI-Expanded)

21. The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis

Muftuoglu M., Oshima J., von Kobbe C., Cheng W., Leistritz D. F., Bohr V. A.

HUMAN GENETICS , cilt.124, sa.4, ss.369-377, 2008 (SCI-Expanded)

22. Intrinsic ssDNA annealing activity in the C-terminal region of WRN

Muftuoglu M., Kulikowicz T., Beck G., Lee J. W., Piotrowski J., Bohr V. A.

BIOCHEMISTRY , cilt.47, sa.39, ss.10247-10254, 2008 (SCI-Expanded)

23. WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks

Cheng W., Muftic D., Muftuoglu M., Dawut L., Morris C., Helleday T., et al.

MOLECULAR BIOLOGY OF THE CELL , cilt.19, sa.9, ss.3923-3933, 2008 (SCI-Expanded)

24. The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging

Stevnsner T., Muftuoglu M., Aamann M. D., Bohr V. A.

MECHANISMS OF AGEING AND DEVELOPMENT , cilt.129, ss.441-448, 2008 (SCI-Expanded)

25. Acetylation Regulates WRN Catalytic Activities and Affects Base Excision DNA Repair

Muftuoglu M., Kusumoto R., Speina E., Beck G., Cheng W., Bohr V. A.

PLOS ONE , cilt.3, sa.4, 2008 (SCI-Expanded)

26. Werner syndrome protein: Functions in the response to DNA damage and replication stress in S-phase

Cheng W., Muftuoglu M., Bohr V. A.

EXPERIMENTAL GERONTOLOGY , cilt.42, sa.9, ss.871-878, 2007 (SCI-Expanded)

27. Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates

Wong H., Muftuoglu M., Beck G., Imam S. Z., Bohr V. A., Wilson D. M.

NUCLEIC ACIDS RESEARCH , cilt.35, sa.12, ss.4103-4113, 2007 (SCI-Expanded)

28. The role of WRN in DNA repair is affected by post-translational modifications

Kusumoto R., Muftuoglu M., Bohr V. A.

MECHANISMS OF AGEING AND DEVELOPMENT , cilt.128, sa.1, ss.50-57, 2007 (SCI-Expanded)

29. Cockayne syndrome group B protein has novel strand annealing and exchange activities

Muftuoglu M., Sharma S., Thorslund T., Stevnsner T., Soerensen M., Brosh R., et al.

NUCLEIC ACIDS RESEARCH , cilt.34, sa.1, ss.295-304, 2006 (SCI-Expanded)

30. Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta

Muftuoglu M., Wong H., Imam S., Wilson D., Bohr V., Opresko P.

CANCER RESEARCH , cilt.66, sa.1, ss.113-124, 2006 (SCI-Expanded)

31. Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations

Muftuoglu M., Elibol B., Dalmizrak O., Ercan A., Kulaksiz G., Ogus H., et al.

MOVEMENT DISORDERS , cilt.19, sa.5, ss.544-548, 2004 (SCI-Expanded)

32. Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells

Selzer R., Nyaga S., Tuo J., May A., Muftuoglu M., Christiansen M., et al.

NUCLEIC ACIDS RESEARCH , cilt.30, sa.3, ss.782-793, 2002 (SCI-Expanded)

33. Phenotypic consequences of mutations in the conserved motifs of the putative helicase domain of the human Cockayne Syndrome Group B gene

Muftuoglu M., Selzer R., Tuo J., Brosh R., Bohr V.

GENE , cilt.283, ss.27-40, 2002 (SCI-Expanded)

34. The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA

Tuo J., Muftuoglu M., Chen C., Jaruga P., Selzer R., Brosh R., et al.

JOURNAL OF BIOLOGICAL CHEMISTRY , cilt.276, sa.49, ss.45772-45779, 2001 (SCI-Expanded)

35. Simple, high-yield purification of xanthine oxidase from bovine milk

Ozer N., Muftuoglu M., Ataman D., Ercan A., Ogus I.

JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS , cilt.39, sa.3, ss.153-159, 1999 (SCI-Expanded)

36. The in vitro effects of the antimalarial drug primaquine, on the activities of some enzymes in human erythrocyte lyzates

Muftuoglu M., ÖZER N.

Turkish Journal of Medical Sciences , cilt.29, sa.4, ss.409-412, 1999 (SCI-Expanded)

37. A simple and sensitive method for the activity staining of xanthine oxidase

Ozer N., Muftuoglu M., Ogus I.

JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS , cilt.36, ss.95-100, 1998 (SCI-Expanded)

Diğer Dergilerde Yayınlanan Makaleler 5

1. Association of Mitochondrial DNA Copy Number Variations with Triple-Negative Breast Cancer: A Potential Biomarker Study

Manto K., Ustun Yilmaz S., PALA KARA Z., KARA H., TOKAT F., AKYERLİ BOYLU C., et al.

DISEASES , cilt.13, sa.6, 2025 (ESCI) Sürdürülebilir Kalkınma

2. Anti-proliferative effects of indomethacin, acemetacin and their tromethamine salts in HCT116 human colon cancer cells

Cihan Üstündağ G., Somuncu B., Müftüoğlu M., Karalı L. N.

JOURNAL OF PHARMACY OF ISTANBUL UNIVERSITY , cilt.51, ss.161-166, 2021 (ESCI) Sürdürülebilir Kalkınma

3. Nadir DNA Onarımı Kusurlu Hastalıkların Genetiği ve Güncel Tedaviler

Müftüoğlu M., Ekmekçioğlu A., Kalyoncu M.

Türkiye Klinikleri Tıbbi Genetik , cilt.1, ss.69-77, 2021 (Hakemli Dergi)

4. 5-Hydroxyuracil Incision Activity Varies According to the Histological Grade of Non-muscle-invasive Bladder Cancer

Keskin M. S., Antmen F. M., Somuncu B., Sağlıcan Y., Doganca T., Öbek C., et al.

UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY , cilt.20, ss.45-48, 2021 (ESCI) Sürdürülebilir Kalkınma

5. Bacillus Calmette-Guerin Increases Base Excision Repair in Bladder Cancer Cells

Keskin M. S., Somuncu B., Müftüoğlu M.

Journal of Urological Surgery , cilt.8, sa.1, ss.8-12, 2021 (Hakemli Dergi) Sürdürülebilir Kalkınma

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 21

1. Gestasyonel diabetes mellitusun mitokondriyal dinamiklere etkisinin değerlendirilmesi.

Abalı S., Öz Arslan D., Güner Yılmaz B., Çelik M., Koç B., Müftüoğlu M., et al.

32. Ulusal Neontoloji Kongresi, Antalya, Türkiye, 17 - 20 Nisan 2025, ss.68-69, (Özet Bildiri)

2. Does gestational diabetes mellitus influence mitochondrial dynamics in offspring?

Abalı S., Öz Arslan D., Güner Yılmaz B., Çelik M., Koç B., Müftüoğlu M., et al.

The 62nd ESPE Annual Meeting , Liverpool, İngiltere, 16 - 18 Kasım 2024, cilt.97, ss.133-134, (Özet Bildiri)

3. Valproik asit ile indüklenen otizm modelinde mitokondriyal dinamiklerin gelişimsel süreçte incelenmesi

ÖZER S., SARI E., ERKAYA M., DARILMAZ İ., ÖZ ARSLAN D., MÜFTÜOĞLU M., et al.

20. Ulusal Sinirbilim Kongresi, İstanbul, Türkiye, 19 Ekim 2022, (Özet Bildiri)

4. Enhanced activity of plasminogen activator inhibitor 1 (PAI-1) in neurodegenerative diseases

MÜFTÜOĞLU M., AĞIRBAŞLI D., Ağırbaşlı M.

ACC Middle East 2022 Together With 13th Emirates Cardiac Society Congress, Dubai, Birleşik Arap Emirlikleri, 07 Ekim 2022, (Özet Bildiri)

5. KALITSAL KANSERLERDE KLİNİK ÖNEMİ BİLİNMEYEN GENOMİK VARYANTLARIN FONKSİYONEL KARAKTERİZASYONU VE SINIFLANDIRILMASI

Üstün Yılmaz S., Özdemir Ö., AĞAOĞLU N. B., HATIRNAZ NG Ö., MÜFTÜOĞLU M., ÖZBEK U.

8.TÜRK TIBBİ ONKOLOJİ KONGRESİ, Antalya, Türkiye, 3 - 07 Kasım 2021, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

6. Fluvastatin Sodium Loaded Nanovesicular Carriers: Formulation Development, Characterization and In vitro Cell Culture Studies

GÜRBÜZ A., GÜNGÖR S., MÜFTÜOĞLU M., Ekmekcioglu A., ERDAL M. S.

CRS2021 Virtual Annual Meeting, Amerika Birleşik Devletleri, 25 Temmuz 2021 - 25 Ekim 2022, (Özet Bildiri)

7. D vitamini takviyesinin serum D vitamini seviyeleri ve telomere etkisi

Ağırbaşlı D., Kalyoncu M., Ağırbaşlı M. A., Müftüoğlu M.

16. Uluslararası Katılımlı Tıbbi Biyoloji ve Genetik Kongresi, Muğla, Türkiye, 27 - 30 Ekim 2019, cilt.1, ss.76, (Özet Bildiri)

8. Association of Vitamin D levels with leukocyte telomere length in postmenopausal women

Kalyoncu M., Ağırbaşlı D., Müftüoğlu M., Onur İ., Ağırbaşlı M.

International Moelcular Medicine Symposium, İstanbul, Türkiye, 16 - 18 Mayıs 2019, cilt.1, ss.101, (Özet Bildiri)

9. Ataksi Telenjiektazi Hastalarının Ebeveynlerinde Enfeksiyonlar ve Lenfosit Alt Grup Bozuklukları

ÖĞÜLÜR İ., Ertüzün T., ÖZEN A. O., UYAR E., KIYKIM A., Başer D., et al.

XXV. Ulusal Allerji ve Klinik İmmünoloji Kongresi, Antalya, Türkiye, 17 - 21 Kasım 2018, (Tam Metin Bildiri)

10. Kasa İnvaze Olmayan Mesane Tümöründe Artmış Apürinik/Apirimidinik Endonükleaz Aktivitesi

KESKİN M. S., SOMUNCU B., ANTMEN F. M., SAĞLICAN Y., ERTÜZÜN T., TUNA M. B., et al.

4. Ulusal Ürolojik Cerrahi Kongresi, Antalya, Türkiye, 31 Ekim - 04 Kasım 2018, (Özet Bildiri)

11. INFECTIONS AND LYMPHOCYTE SUBSET ALTERATIONS IN ATAXIA TELANGIECTASIA MUTATED KINASE CARRIERS

ÖĞÜLÜR İ., Ertüzün T., ÖZEN A. O., UYAR E., KIYKIM A., Başer D., et al.

18th Biennial Meeting of ESID, Lizbon, Portekiz, 24 - 27 Ekim 2018, (Özet Bildiri)

12. Enhanced Apurinic/Apyrimidinic Endonuclease Activity in Non-Muscle Invasive Bladder Cancer

KESKİN M. S., SOMUNCU B., ANTMEN M., SAĞLICAN Y., ERTÜZÜN T., Tuna M. B., et al.

36th World Congress of Endourology, Paris, Fransa, 20 - 23 Eylül 2018, (Özet Bildiri) Sürdürülebilir Kalkınma

13. Identification and characterization of small molecule inhibitors targeting DNA polymerase gamma for the treatment of cancers deficient in mismatch repair

Pamukcu C., Keskin N., Aydin D., Gulser I. E., Deniz E., Erman M. B., et al.

40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life, Berlin, Almanya, 4 - 09 Temmuz 2015, cilt.282, ss.270-271, (Özet Bildiri) Sürdürülebilir Kalkınma

14. REAL TIME AND QUANTITATIVE ASSESSMENT OF THE EFFECTS OF DIFFERENT OVARIAN STIMULATION PROTOCOLS ON THE PROLIFERATION AND CELL CYCLE KINETICS OF GRANULOSA CELLS USING A NEW IMPEDENCE-BASED SYSTEM.

Oktem O., Muftuoglu M., Senbabaoglu F., Urman B.

International-Federation-of-Fertility-Societies 21st World Congress on Fertility and Sterility / 69th Annual Meeting of the American-Society-for-Reproductive-Medicine, Massachusetts, Amerika Birleşik Devletleri, 12 - 17 Ekim 2013, cilt.100, (Özet Bildiri)

15. The involvement of Cockayne syndrome B protein in base excision repair

Muftuoglu M., Aamann M. D., Stevnsner T., Bohr V. A.

38th Congress of the Federation-of-European-Biochemical-Societies (FEBS), Saint Peter, Guernsey Ve Alderney, 6 - 11 Temmuz 2013, cilt.280, ss.62, (Özet Bildiri)

16. Real-time analysis of the growth of human granulosa cells using an impedance-based signal processing system: a new technology for translational research in human reproduction

Oktem O., Muftuoglu M., Senbabaoglu F., Urman B.

29th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), London, Kanada, 7 - 10 Temmuz 2013, cilt.28, ss.54-55, (Özet Bildiri)

17. Effect of pharmacologic inhibition of c-Jun N-terminal kinase (JNK) signaling pathway on cell proliferation and cell cycle progression in human granulosa cell tumor

Oktem O., Muftuoglu M., Senbabaoglu F., Urman B.

49th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Illinois, Amerika Birleşik Devletleri, 31 Mayıs - 04 Haziran 2013, cilt.31, (Özet Bildiri)

18. Base excision repair pathway at telomeric DNA

Muftuoglu M., Opresko P., Bohr V.

31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.54, (Özet Bildiri)

19. Mitochondrial complex I and IV activities, ND2, ND4 gene mutations and expressions in idiopathic Parkinson's disease

Ercan A., Kulaksiz G., Muftuoglu M., Dalmizrak O., Ogus H., Cavdar L., et al.

31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.244-245, (Özet Bildiri)

20. Mitochondrial complex I and complex IV activities in lymphocytes from patients with Parkin gene mutations

Dalmizrak O., Muftuoglu M., Atac F., Ogus J., Ozer N., Elibol B.

7th International Congress of Parkinsons Disease and Movement Disorders, MIAMI, FLORIDA, 10 - 14 Kasım 2002, cilt.17, (Özet Bildiri)

21. The effects of oxidative stress on the redox system of the human erythrocyte

Ogus I., Balk M., Aksoy Y., MÜFTÜOĞLU M., Ozer N.

NATO Advanced Study Institute on Free Radicals, Oxidative Stress, and Antioxidants - Pathological and Physiological Significance, Antalya, Türkiye, 24 Mayıs - 04 Haziran 1997, ss.25-37, (Tam Metin Bildiri)

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