Prof. Dr. ÖZDEN HATIRNAZ NG

1. Clinical management of three JMML siblings with germline CBL variation

Agaoglu N. B., Yalcın K., Unal B., Onder G., Celen S. S., Zhumatayev S., et al.

Cancer Genetics , cilt.292-293, ss.120-123, 2025 (SCI-Expanded)

2. Managing CDH1 Cancer Risks in a Child: Complex Decision Making in a Family With Hereditary Diffuse Gastric Cancer

Agaoglu N. B., HATIRNAZ NG Ö., Zemheri I. E., Unal B., Gerenli N., Tosun I., et al.

American Journal of Medical Genetics, Part A , cilt.197, sa.2, 2025 (SCI-Expanded)

3. Status of IKZF1 Deletions in Diagnose and Relapsed Pediatric B-ALL Patients.

Erbilgin Y., Firtina S., Kirat E., Khodzhaev K., Karakas Z., Ünüvar A., et al.

Biochemical genetics , 2025 (SCI-Expanded)

4. Statistical analysis of genomic in-silico pathogenicity predictors for the characterization of VUS in rare and undiagnosed disorders

AYDIN E., Ergun B., AKGÜN DOĞAN Ö., ALANAY Y., HATIRNAZ NG Ö., ÖZDEMİR Ö.

EUROPEAN JOURNAL OF HUMAN GENETICS , ss.1172, 2024 (SCI-Expanded)

5. Statistical analysis of genomic in-silico pathogenicity predictors for the characterization of VUS in rare and undiagnosed disorders

AYDIN E., Ergun B., AKGÜN DOĞAN Ö., ALANAY Y., HATIRNAZ NG Ö., ÖZDEMİR Ö.

EUROPEAN JOURNAL OF HUMAN GENETICS , ss.1172, 2024 (SCI-Expanded)

6. Long-term immunological changes after corrective cardiac surgery

BİLGİÇ ELTAN S., Amirov R., Babayeva R., Altunbas M. Y., Karakurt T., CAN S., et al.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY , cilt.100, sa.6, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

7. Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon

Delgado-Vega A. M., Cederroth H., Taylan F., Ekholm K., Ek M., Thonberg H., et al.

NATURE GENETICS , sa.11, ss.2287-2294, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

8. **Molecular and In Silico Analysis of the CHEK2 Gene in Individuals with High Risk of Cancer Predisposition from Turkiye**

ÖZDEMİR Ö., Bychkovsky B. L., Unal B., ÖNDER G., Amanvermez U., AYDIN E., et al.

CANCERS , cilt.16, sa.22, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

9. Rapid genome sequencing for critically ill infants: an inaugural pilot study from Turkey.

Guner Yilmaz B., Akgun-Dogan Ö., Ozdemir Ö., Yuksel B., Hatirnaz Ng Ö., Bilguvar K., et al.

Frontiers in pediatrics , cilt.12, ss.1412880, 2024 (SCI-Expanded)

10. Genomic disparity impacts variant classification of cancer susceptibility genes in Turkish breast cancer patients

Agaoglu N. B., Unal B., Hayes C. P., Walker M., HATIRNAZ NG Ö., Doganay L., et al.

CANCER MEDICINE , cilt.13, sa.3, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

11. Memantine and SKF82958 but not an enriched environment modulate naloxone-precipitated morphine abstinence syndrome without affecting hippocampal tPA mRNA levels in rats

Aslan A., Hatirnaz-Ng Ö., Tasar O., Ozbek U., Yamanturk-Celik P.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR , cilt.234, 2024 (SCI-Expanded)

12. A new line method; A direct test in spinal muscular atrophy screening for DBS

Kubar A., Temel S. G., Beken S., Onder G., Hatirnaz Ö., Korkmaz A., et al.

Molecular Genetics and Genomic Medicine , cilt.11, sa.12, 2023 (SCI-Expanded)

13. Impact of TP53 gene variants on prognosis and survival of childhood acute lymphoblastic leukemia.

Firtina S., Erbilgin Y., Hatirnaz Ng Ö., Karaman S., Karakas Z., Celkan T. T., et al.

Scandinavian journal of clinical and laboratory investigation , cilt.83, sa.3, ss.187-193, 2023 (SCI-Expanded)

14. Perception and management of cancer predisposition in pediatric cancer centers: A European-wide questionnaire-based survey

Lazic J., Haas O. A., Özbek U., Ripperger T., Byrjalsen A., Te Kronnie G., et al.

Pediatric Blood and Cancer , cilt.70, sa.5, 2023 (SCI-Expanded)

15. Obstacles and expectations of rare disease patients and their families in Turkiye: ISTisNA project survey results

Hatirnaz Ng Ö., Sahin I., Erbilgin Y., Ozdemir Ö., Yucesan E., Erturk N., et al.

FRONTIERS IN PUBLIC HEALTH , cilt.10, 2023 (SCI-Expanded)

16. Concurrent Pathogenic Variants of BRCA1, MUTYH and CHEK2 in a Hereditary Cancer Family

Agaoglu N. B., HATIRNAZ NG Ö., Unal B., AKGÜN DOĞAN Ö., Amanvermez U., Yildiz J., et al.

CANCER GENETICS , cilt.268-269, ss.128-136, 2022 (SCI-Expanded)

17. Tackling TKI resistance in AML: A commentary on "Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML." by Yamatani et al.

Hatırnaz Ng Ö., Eşkazan A. E.

Translational oncology , cilt.19, ss.101394, 2022 (SCI-Expanded)

18. Determining T and B Cell development by TREC/KREC analysis in primary immunodeficiency patients and healthy controls

Senturk G., Ng Y. Y., Eltan S. B., Baser D., Ogulur I., Altindirek D., et al.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY , cilt.95, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

19. Primary antibody deficiencies in Turkey: molecular and clinical aspects

Firtina S., Ng Y. Y., HATIRNAZ NG Ö., Kiykim A., Ozek E. Y., Kara M., et al.

IMMUNOLOGIC RESEARCH , cilt.70, sa.1, ss.44-55, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

20. Zinc finger protein 384 (ZNF384) impact on childhood mixed phenotype acute leukemia and B-cell precursor acute lymphoblastic leukemia

Sudutan T., ERBİLGİN Y., HATIRNAZ NG Ö., KARAMAN S., KARAKAŞ Z., Kucukcankurt F., et al.

LEUKEMIA & LYMPHOMA , cilt.63, sa.12, ss.2931-2939, 2022 (SCI-Expanded)

21. Mutational landscape of SARS-CoV-2 genome in Turkey and impact of mutations on spike protein structure.

Hatirnaz N., Akyoney S., Sahin I., Soykam H., Bayram A., Ozdemir Ö., et al.

PloS one , cilt.16, sa.12, 2021 (SCI-Expanded)

22. Prognostic evidence of LEF1 isoforms in childhood acute lymphoblastic leukemia.

ERBİLGİN Y., Ng Ö., Can I., Firtina S., Kucukcankurt F., KARAMAN S., et al.

International journal of laboratory hematology , cilt.43, sa.5, ss.1093-1103, 2021 (SCI-Expanded)

23. Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice.

Turan R. D., Tastan C., Kancagi D. D., Yurtsever B., Karakus G. S., Ozer S., et al.

Scientific reports , cilt.11, sa.1, ss.15799, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

24. Preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates

Sir Karakus G., Tastan C., Dilek Kancagi D., Yurtsever B., Tumentemur G., Demir S., et al.

SCIENTIFIC REPORTS , cilt.11, sa.1, 2021 (SCI-Expanded)

25. Mutational landscape of severe combined immunodeficiency patients from Turkey

Çekiç Ş., Ng Y. Y., Ng Ö., Kıykım A., Özen A. O., Özen A. O., et al.

INTERNATIONAL JOURNAL OF IMMUNOGENETICS , cilt.47, sa.6, ss.529-538, 2020 (SCI-Expanded)

26. Copy-number variations in adult patients with chronic immune thrombocytopenia.

YÜCESAN E., Ng Ö., Yalniz F. F., Yilmaz H., SALİHOĞLU A., Sudutan T., et al.

Expert review of hematology , cilt.13, sa.11, ss.1277-1287, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

27. The potential protective roles of zinc, selenium and glutathione on hypoxia-induced TRPM2 channel activation in transfected HEK293 cells

Ergun D. D., Dursun S., PASTACI ÖZSOBACI N., HATIRNAZ NG Ö., NAZIROĞLU M., ÖZÇELİK D.

JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION , cilt.40, sa.6, ss.521-530, 2020 (SCI-Expanded)

28. Hydrogen Sulphide and Nitric Oxide Cooperate in Cardioprotection Against Ischemia/Reperfusion Injury in Isolated Rat Heart.

ÜSTÜNOVA S., TAKIR S., YILMAZER N., Bulut H., ALTINDİREK D., HATIRNAZ NG Ö., et al.

In vivo (Athens, Greece) , cilt.34, sa.5, ss.2507-2516, 2020 (SCI-Expanded)

29. Lymphoma Predisposing Gene in an Extended Family: CD70 Signaling Defect

Khodzhaev K., Bay S. B., Kebudi R., ALTINDİREK D., Kaya A., Erbilgin Y., et al.

JOURNAL OF CLINICAL IMMUNOLOGY , cilt.40, sa.6, ss.883-892, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

30. PTEN and AKT1 Variations in Childhood T-Cell Acute Lymphoblastic Leukemia

Kucukcankurt F., Erbilgin Y., Firtina S., Hatirnaz Ö., Karakas Z., Celkan T., et al.

TURKISH JOURNAL OF HEMATOLOGY , cilt.37, sa.2, ss.98-103, 2020 (SCI-Expanded)

31. Prognostic gene alterations and clonal changes in childhood B-ALL.

ERBİLGİN Y., Firtina S., Mercan S., Ng Ö., KARAMAN S., Tasar O., et al.

Leukemia research , cilt.83, ss.106159, 2019 (SCI-Expanded)

32. Deep sequencing of BCR-ABL1 kinase domain mutations in chronic myeloid leukemia patients with resistance to tyrosine kinase inhibitors.

ERBİLGİN Y., Eskazan A. E., HATIRNAZ NG Ö., SALİHOĞLU A., ELVERDİ T., Firtina S., et al.

Leukemia & lymphoma , cilt.60, sa.1, ss.200-207, 2019 (SCI-Expanded)

33. A novel pathogenic frameshift variant of CD3E gene in two T-B+ NK+ SCID patients from Turkey.

Firtina S., Ng Y. Y., Ng Ö., Nepesov S., Yesilbas O., Kilercik M., et al.

Immunogenetics , cilt.69, sa.10, ss.653-659, 2017 (SCI-Expanded)

34. Dysregulation of the DKK1 gene in pediatric B-cell acute lymphoblastic leukemia

Firtina S., Hatirnaz Ng Ö., Erbilgin Y., Ozbek U., Sayitoglu M.

TURKISH JOURNAL OF MEDICAL SCIENCES , cilt.47, sa.1, ss.357-363, 2017 (SCI-Expanded)

35. A Possible Role for WNT5A Hypermethylation in Pediatric Acute Lymphoblastic Leukemia

HATIRNAZ NG Ö., Firtina S., Can I., KARAKAŞ Z., Agaoglu L., DOĞRU Ö., et al.

TURKISH JOURNAL OF HEMATOLOGY , cilt.32, sa.2, ss.127-135, 2015 (SCI-Expanded)

36. Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia

HATIRNAZ NG Ö., ERBİLGİN Y., Firtina S., Celkan T., KARAKAŞ Z., Aydogan G., et al.

BLOOD CANCER JOURNAL , cilt.4, 2014 (SCI-Expanded)

37. LOCAL RENIN-ANGIOTENSIN SYSTEM IN NORMAL HEMATOPOIETIC AND MULTIPLE MYELOMA-RELATED PROGENITOR CELLS

Haznedaroglu I., Uz B., Ozcebe O., Buyukasik Y., Goker H., Aksu S., et al.

HAEMATOLOGICA , cilt.98, ss.768, 2013 (SCI-Expanded)

38. Identification of Interconnected Markers for T-Cell Acute Lymphoblastic Leukemia

Maiorov E. G., Keskin O., Ng Ö., Ozbek U., Gursoy A.

BIOMED RESEARCH INTERNATIONAL , 2013 (SCI-Expanded)

39. Upregulation of T-Cell-Specific Transcription Factor Expression in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

SAYİTOĞLU M., ERBİLGİN Y., HATIRNAZ NG Ö., Yildiz I., Celkan T., Anak S., et al.

TURKISH JOURNAL OF HEMATOLOGY , cilt.29, sa.4, ss.325-333, 2012 (SCI-Expanded)

40. Genetic alterations in members of the Wnt pathway in acute leukemia

Erbilgin Y., Ng Ö., Mavi N., Ozbek U., Sayitoglu M.

Leukemia and Lymphoma , cilt.53, sa.3, ss.508-510, 2012 (SCI-Expanded)

41. Definition of C282Y mutation in a hereditary hemochromatosis family from Turkey

Yoenal O., Hatirnaz Ö., Akyuez F., Koroglu G., Ozbeik U., Cefle K., et al.

Turkish Journal of Gastroenterology , cilt.18, sa.1, ss.53-57, 2007 (SCI-Expanded)

42. HFE gene mutation, chronic liver disease, and iron overload in Turkey

Yoenal O., Hatirnaz Ö., Akyuez F., Oezbek U., Demir K., Kaymakoglu S., et al.

Digestive Diseases and Sciences , cilt.52, sa.11, ss.3298-3302, 2007 (SCI-Expanded)

43. The SOCS-1 gene methylation in chronic myeloid leukemia patients

Hatirnaz M., Ure U., Ar C., Akyerli C., Soysal T., Ferhanoglu B., et al.

American Journal of Hematology , cilt.82, sa.8, ss.729-730, 2007 (SCI-Expanded)

Yayınlar & Eserler