Doç. Dr. AHMET CAN TİMUÇİN

Yayın Ağı

Makaleler 33

1. Nanostructured Electrochemical Biosensor for Highly Sensitive Copeptin Detection as a Cardiac Biomarker

Nuhoğlu D., Guney Kekec G., Senturk B., Karadeniz K. B., Camadan E. E. I., Pendar A., et al.

ACS OMEGA , 2026 (SCI-Expanded, Scopus)

2. Impact of LAMA5 Variants on Immune Cell Infiltration Using 2D Blood Brain Barrier Culture Model of Multiple Sclerosis (P2-18.004)

Siva A., Voyvoda U., Cotuk K., Efe H., Karisik S. N., Reda M., et al.

NEUROLOGY , cilt.106, sa.11_Supplement_1, ss.1-2, 2026 (SCI-Expanded, Scopus)

3. Peptide Design for Targeting BTB Domain Homodimerization of BACH2: Complementary In Silico and In Vitro Approaches

Acar E., Başağa H., Timuçin E., Timuçin A. C.

ACS OMEGA , sa.6c01122, ss.1-26, 2026 (SCI-Expanded, Scopus)

4. Systematic Evaluation of AlphaFold2 and OpenFold3 on Protein–Peptide Complexes

Fayetorbay R., Timuçin A. C., Timuçin E.

bioRxiv , ss.1-19, 2026 (Hakemsiz Dergi)

5. Indole ring linked thiazolidone hybrid molecules as potent tubulin inhibitors

Abba A., Unal N., Dede Z. S., Bedir I., Telci D., Aru B., et al.

LETTERS IN DRUG DESIGN AND DISCOVERY , ss.1-18, 2026 (SCI-Expanded, Scopus)

6. Molecular Consequences of CCN6 Variants Encoding WISP3 in Progressive Pseudorheumatoid Dysplasia

Guven Tasbicen G., Tufan A., Savsar B., Bulbul A. A., Tonbul Z., Guzel E., et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES , cilt.26, ss.1-33, 2025 (SCI-Expanded, Scopus)

7. Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF-Trap

Destan E., Turkut E., Aldeniz A., Kang J., Tosha T., Yabashi M., et al.

SMALL STRUCTURES , ss.1-14, 2025 (SCI-Expanded)

8. Peptide-Based Regulation of TNF-α-Mediated Cytotoxicity

TEMUR B. Z., TİMUÇİN V. C., ATİK A. E., KOCAGÖZ Z. T., CAN Ö.

Biomolecules , cilt.15, sa.4, 2025 (SCI-Expanded, Scopus)

9. A rare case of uncharacterized autoinflammatory disease: Patient carrying variations in NLRP3 and TNFRSF1A genes.

Kilinc O. C., Gayibova K., Onen M. O., Onat U. I., Bülbül A. A., Timucin A. C., et al.

American journal of medical genetics. Part A , cilt.194, sa.10, 2024 (SCI-Expanded, Scopus)

10. Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF-Trap

Destan E., Turkut E., Aldeniz A., Kang J., Tosha T., Yabashi M., et al.

BIORXIV , sa.-, ss.1-28, 2024 (Hakemsiz Dergi)

11. Structure based computational RNA design towards MafA transcriptional repressor implicated in multiple myeloma

Akdeniz G. Y., Timuçin A. C.

JOURNAL OF MOLECULAR GRAPHICS AND MODELLING , cilt.132, ss.1-17, 2024 (SCI-Expanded, Scopus)

12. Var3PPred: variant prediction based on 3-D structure and sequence analyses of protein-protein interactions on autoinflammatory diseases

Bülbül A. A., TİMUÇİN E., TİMUÇİN A. C., SEZERMAN O. U., TAHİR TURANLI E.

PeerJ , cilt.12, sa.5, 2024 (SCI-Expanded, Scopus)

13. Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex

Altiner P., Çınaroğlu S. S., Timuçin A. C., Timucin E.

SCIENTIFIC REPORTS , cilt.13, sa.1, 2023 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

14. Detection of a rare variant in PSTPIP1 through three generations in a family with an initial diagnosis of FMF/MKD-overlapping phenotype

Özkılınç Önen M., Onat U. İ., Uğurlu S., Timuçin A. C., Öz Arslan D., Everest E., et al.

RHEUMATOLOGY , sa.9, ss.3188-3196, 2023 (SCI-Expanded, Scopus)

15. Selective cytotoxicity of chemical composition of Spirulina platensis extract in endometrial cells: In vitro and in silico approach

Atasever Arslan B., Yılancıoğlu K., Timuçin A. C., Kalkan Z., Kuşoğlu Gültekin S., Çetiner S.

KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE , cilt.0, 2022 (TRDizin)

16. Modeling and dynamical analysis of the full-length structure of factor XII with zinc.

Kılınç E., Can Timucin A. C., Selim Cinaroglu S., Timucin E.

Journal of molecular modeling , cilt.28, sa.5, ss.129, 2022 (SCI-Expanded, Scopus)

17. Toward Compilation of Balanced Protein Stability Data Sets: Flattening the Delta Delta G Curve through Systematic Enrichment

Kebabci N., TİMUÇİN A. C., TİMUÇİN E.

JOURNAL OF CHEMICAL INFORMATION AND MODELING , cilt.62, sa.5, ss.1345-1355, 2022 (SCI-Expanded, Scopus)

18. Bridging the Bridging Imidazolate in the Bimetallic Center of the Cu/Zn SOD1 and ALS

TİMUÇİN A. C., Cinaroglu S. S., SEZERMAN O. U., TİMUÇİN E.

FRONTIERS IN CHEMISTRY , cilt.9, 2021 (SCI-Expanded, Scopus)

19. Towards Compilation of Balanced Protein Stability Datasets: Flattening the ΔΔG Curve through Systematic Under-sampling

Timuçin A. C., Timuçin E.

BIORXIV , cilt.0, ss.1-31, 2021 (Hakemsiz Dergi)

20. Molecular Dynamics and MM-PBSA Studies for Deciphering Molecular Interactions of Valproic Acid with CYP2C9 Mutants F114L and I207T

Timuçin A. C.

Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi , cilt.25, ss.64-73, 2021 (TRDizin)

21. Structure based peptide design, molecular dynamics and MM-PBSA studies for targeting C terminal dimerization of NFAT5 DNA binding domain

Timucin A. C.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING , cilt.103, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

22. Conserved Amino Acids in HCoV-HKU1 and SARS-Cov2 at RNA-dependent RNA Polymerase (RdRp) Motifs

Timuçin A. C.

Anatolian Journal of Biology , cilt.2, ss.17-24, 2021 (Hakemli Dergi) Sürdürülebilir Kalkınma

23. Computational Modeling of Trans-Zeatin as a Novel Target of Adenosine A2A Receptor: Insights into Molecular Interactions

Timuçin A. C.

The Journal of Neurobehavioral Sciences , cilt.7, ss.118-129, 2020 (Hakemli Dergi)

24. The sex-dependent anti-depressant-like effects of zeatin in rat behavioral despair model as a candidate A2A receptor ligand

Oz P., Timucin A. C., Teomete S., Akpunar F., Tufanc C., Ogur D., et al.

NEUROSCIENCE LETTERS , cilt.734, 2020 (SCI-Expanded, Scopus)

25. Immunotherapy approaches on innate immunity for SARS-Cov-2

Arslan B. A., Timucin A. C.

ACTA VIROLOGICA , cilt.64, sa.4, ss.389-395, 2020 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

26. Selective targeting of antiapoptotic BCL-2 proteins in cancer

Timucin A. C., Basaga H., Kutuk O.

MEDICINAL RESEARCH REVIEWS , cilt.39, sa.1, ss.146-175, 2019 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

27. Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-kappa B pathway and anti-apoptotic Bcl-2

Timucin A. C., Basaga H.

FREE RADICAL BIOLOGY AND MEDICINE , cilt.111, ss.209-218, 2017 (SCI-Expanded, Scopus)

28. AMP-Activated Protein Kinase Couples 3-Bromopyruvate-Induced Energy Depletion to Apoptosis via Activation of FoxO3a and Upregulation of Proapoptotic Bcl-2 Proteins

Bodur C., Karakas B., Timucin A. C., Tezil T., Basaga H.

MOLECULAR CARCINOGENESIS , cilt.55, sa.11, ss.1584-1597, 2016 (SCI-Expanded, Scopus)

29. SIRT6 Is a Positive Regulator of Aldose Reductase Expression in U937 and HeLa cells under Osmotic Stress: In Vitro and In Silico Insights

Timucin A. C., Basaga H.

PLOS ONE , cilt.11, sa.8, 2016 (SCI-Expanded, Scopus)

30. Screening of new antileukemic agents from essential oils of algae extracts and computational modeling of their interactions with intracellular signaling nodes

Ataseyer-Arslan B., Yilancioglu K., Kalkan Z., Timucin A. C., Gur H., Isik F. B., et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES , ss.120-131, 2016 (SCI-Expanded) Sürdürülebilir Kalkınma

31. SIRT1 contributes to aldose reductase expression through modulating NFAT5 under osmotic stress: In vitro and in silico insights

Timucin A. C., Bodur C., Basaga H.

CELLULAR SIGNALLING , cilt.27, sa.11, ss.2160-2172, 2015 (SCI-Expanded, Scopus)

32. ANTIBODY ARRAY-BASED IMMUNOSENSOR FOR DETECTING CARDIOVASCULAR DISEASE RISK MARKERS

Timucin C., Gul O., Kutuk O., Basaga H.

JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY , cilt.33, sa.3, ss.275-290, 2012 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

33. Identification of biomarkers for the antiangiogenic and antitumour activity of the superoxide dismutase 1 (SOD1) inhibitor tetrathiomolybdate (ATN-224)

Donate F., Juarez J. C., Burnett M. E., Manuia M. M., Guan X., Shaw D. E., et al.

BRITISH JOURNAL OF CANCER , cilt.98, sa.4, ss.776-783, 2008 (SCI-Expanded, Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 18

1. Investigation of Multiple Sclerosis Associated LAMA5 Variants on Endothelial Barrier Function and Immune-Cell Transmigration

Voyvoda U., Cotuk K., Efe H., Ustu T., Çakıcı B., Çelik E., et al.

10th International Congress of the Molecular Biology Association of Türkiye (MolBiyoKon’26), İstanbul, Türkiye, 17 - 19 Eylül 2026, ss.1-2, (Özet Bildiri)

2. Rational Design of Fc-Binding Peptide Ligands as Next-Generation Alternatives to Protein A for Antibody Purification

Polat T., Eyüpoğlu A. E., Timuçin A. C., Erman B., Kocagöz T., Can Ö.

38th EPS European Peptide Symposium, Vienna, Avusturya, 6 - 11 Eylül 2026, ss.1, (Özet Bildiri)

3. Towards Mono-Functionalized Phthalocyanines Designed to be Anchored at the Active Site of Enzymes

Alagha H., TİMUÇİN E., TİMUÇİN A. C., DUMOULIN İŞÇİ F. A. C., Ricoux R., İŞCİ Ü.

36. Ulusal Kimya Kongresi (UKK2025), 31 Ağustos - 03 Eylül 2025, (Özet Bildiri)

4. Towards mono-functionalized phthalocyanines designed to be anchored at the active site of enzymes

Alaghaa H. Z., Timuçin A. C., Timuçin E., Dumoulin F., Ricoux R., İşçi Ü.

36th National Chemistry Congress (UKK2025), Van, Türkiye, 31 Ağustos - 03 Eylül 2025, ss.1, (Özet Bildiri)

5. Molecular Docking, Weak Interaction, and Molecular Dynamics Studies of Novel Chalcone-Based Structures as Potential Inhibitors of Tubulin and EGFR for Cancer Therapy

Yıldırım Akdeniz G., Timuçin A. C., Başağa S. H.

33rd ISMB (Intelligent Systems for Molecular Biology) Conference/European Conference on Computational Biology (the 24th Annual Conference), Liverpool, İngiltere, 20 - 24 Temmuz 2025, ss.1, (Özet Bildiri)

6. Discovery of Peptide-based Inhibitor Targeting the Human IL18:IL18Rα Complex

Düvenci Z. Ş., Timuçin A. C., Timuçin E.

6th INTERNATIONAL MOLECULAR IMMUNOLOGY & IMMUNOGENETICS CONGRESS (MIMIC-VI), İstanbul, Türkiye, 28 Nisan - 30 Mayıs 2025, ss.1-2, (Özet Bildiri)

7. Impact of LAMA5 Variants on Immune Cell Infiltration using 2D Blood Brain Barrier Culture Model of Multiple Sclerosis

Voyvoda U., Karisik S. N., Reda M. D., Efe H., Cotuk ., Cakici B., et al.

6th International Molecular Immunology and Immunogenetics Congress (MIMIC-VI), İstanbul, Türkiye, 28 - 30 Nisan 2025, ss.1-2, (Özet Bildiri)

8. Discovery of Peptide-based Inhibitor Targeting the Human IL18:IL18Rα Complex

Düvenci Z. Ş., Timuçin A. C., Timuçin E.

17th The International Symposium on Health Informatics and Bioinformatics (HIBIT), İstanbul, Türkiye, 18 - 20 Aralık 2024, ss.1-2, (Özet Bildiri)

9. Novel Approaches in Rational Peptide Design for Recognition of FABP3 and Myoglobin in Cardiac Biosensors

Karadeniz K. B., Şentürk B., Timuçin A. C., Kocagöz Z. T., Camadan E. E., Can Ö.

ODTU MEMS Center 3rd BioMEMS and Microfluidic Technologies Workshop, Ankara, Türkiye, 10 - 11 Haziran 2024, (Yayınlanmadı)

10. A rare case of uncharacterised autoinflammatory disease: patient carrying variations in NLRP3 and TNFRSF1A genes

Kılınç Ö. C., Gayibova K., Durucan İ., Özkılınç Önen M., Onat U. İ., Bülbül A., et al.

European Congress of Rheumatology, Vienna, Avusturya, 12 - 15 Haziran 2024, (Yayınlanmadı)

11. Genetic and Functional Activity Analyses of ADA2 in Patients with Deficiency of Adenosine Deaminase 2

Everest E., Ozkilinc Onen M., Demirci T., Timuçin A. C., Sahin S., Kasapcopur O., et al.

American Society of Human Genetics Annual Meeting, Washington, Amerika Birleşik Devletleri, 1 - 05 Kasım 2023, ss.258, (Özet Bildiri)

12. Classification of Variants in Systemic Autoinflammatory Diseases using 3D Structures and Protein-protein Interactions

Bülbül A., Timuçin E., Timuçin A. C., Sezerman O. U., Tahir Turanlı E.

American Society of Human Genetics Annual Meeting , Washington, Amerika Birleşik Devletleri, 1 - 05 Kasım 2023, ss.516, (Özet Bildiri)

13. Computational Design of RNA Based Modulators Targeting Maf-A protein for Multiple Myolema

Yıldırım Akdeniz G., Başağa S. H., Timuçin A. C.

Intelligient Systems for Molecular Biology/European Conference on Computational Biology 2023, Lyon, Fransa, 23 - 27 Temmuz 2023, (Yayınlanmadı)

14. Transkripsiyon faktörlerinin hedeflenmesi için yapı tabanlı peptit tasarımı, moleküler dinamik ve MM-PBSA çalışmaları

Timuçin A. C.

10.Ulusal Moleküler Biyoloji ve Biyoteknoloji Kongresi, İstanbul, Türkiye, 17 - 19 Aralık 2021, (Yayınlanmadı)

15. Computational design of a peptide targeting homodimerization of BACH2 BTB domain using molecular dynamics and MM-PBSA studies

Timuçin A. C.

4th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2021), Ankara, Türkiye, 24 - 26 Kasım 2021, ss.1-2, (Özet Bildiri)