Prof. Dr. MERT ÜLGEN

Yayın Ağı

Makaleler 51

1. Discovery of novel potent human chondrosarcoma (SW1353) inhibitors: 4-(2/3/4-pyridyl)thiazole 2-acetamide derivatives

COŞKUN G. P., Sahin Z., Erdogan O., Cevik O., Biltekin S. N., YURTTAŞ L., et al.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1273, 2023 (SCI-Expanded, Scopus)

2. In silico studies and in vitro microsomal metabolism of potent MetAP2 inhibitor and in vivo tumor suppressor for prostate cancer: A thioether-triazole hybrid

Coşkun G., Birgül K., Evren A. E., Küçükgüzel Ş., Ülgen M.

Acıbadem Üniversitesi Sağlık Bilimleri Dergisi , cilt.14, sa.1, ss.10-23, 2023 (TRDizin)

3. Formation of N-Oxide metabolites from isoniazid hydrazones of substituted benzaldehydes by hepatic washed pig microsomal preparations

COŞKUN G. P., Algin E. G., KARAKOÇ J. C., Erbul B. T., ÜLGEN M.

Journal of Research in Pharmacy , cilt.27, sa.1, ss.241-250, 2023 (Scopus, TRDizin)

4. Synthesis, structure elucidation and in vitro microsomal metabolism of adamantane hydrazide-hydrazone derivatives

COŞKUN G. P., Erbul B. T., KARAKOÇ J. C., ÜLGEN M.

Acta Pharmaceutica Sciencia , cilt.61, sa.1, ss.65-79, 2023 (Scopus)

5. Synthesis, Structure Elucidation and Biological Activity of New Hybrid Hydrazone-Amide Compounds

Coşkun G. P., Aklamuz A., İnce U., ULGEN M.

Cumhuriyet Science Journal , cilt.43, sa.3, ss.384-390, 2022 (TRDizin)

6. Formation of an N-oxide metabolite following metabolism of 1-(3-chlorobenzyl)[1,2,4] triazolo[4,3-a]quinoxaline by in vitro rat liver microsomal preparations

COŞKUN G. P., SELLİTEPE H. E., KAHVECİ B., ÜLGEN M., DOĞAN İ. S.

Acta Pharmaceutica Sciencia , cilt.60, sa.4, ss.437-449, 2022 (Scopus)

7. Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease

Shukur K. T., Ercetin T., Luise C., Sippl W., Sirkecioğlu O., ÜLGEN M., et al.

ARCHIV DER PHARMAZIE , cilt.354, sa.5, 2021 (SCI-Expanded, Scopus)

8. Studies on the Metabolism of Nitrogen Compounds by Prof J. W. Gorrod

ÜLGEN M., Sevinc N.

CURRENT DRUG METABOLISM , cilt.18, sa.4, ss.291-305, 2017 (SCI-Expanded, Scopus)

9. Simultaneous quantitative determinations of fluticasone propionate and salmeterol xinafote in diskus inhalers

Duran A., Dogan H., ÜLGEN M.

Drug Metabolism Letters , cilt.8, sa.1, ss.31-35, 2014 (Scopus)

10. Development of Thin Layer and High Performance Liquid Chromatographic Methods for The Analysis of Colourings Substances Used in the Printing Inks

Ülgen M., Yenidoğan S., Oktav M.

Asian Journal Of Chemistry , cilt.21, ss.6156-6166, 2009 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

11. The Evaluation of Printability and Biochemical Stability of 4’-Chlorophenylazo-2-Naphtole for use as a Printing Dye

Ülgen M., Oktav M.

Surface Coatings International , cilt.3, sa.88, ss.185-188, 2005 (SCI-Expanded)

12. The determination of stability constants of para substituted n-benzylideneaniline metal complexes by a potentiometric method

Bilgiç D., Pekin M., KARADERİ S., Ülgen M.

Reviews in Analytical Chemistry , cilt.23, sa.2, ss.107-119, 2004 (SCI-Expanded, Scopus)

13. Organizmamızı tehdit eden bir bileşik : Nikotin

Yılmaz F., Ülgen M.

Kimya Teknolojileri , cilt.17, ss.40-43, 2002 (Hakemli Dergi)

14. Yüksek Basınçlı Sıvı Kromatografisinin İlaç Endüstrisinde Kullanımı

Yılmaz F., Ülgen M.

Kimya Teknolojileri , cilt.23, ss.46-51, 2002 (Hakemli Dergi)

15. Karton ambalaj sektöründe sağlığı ve işgüvenliğini olumsuz etkileyen faktörlerin önlenmesine yönelik inceleme

Oktav M., Şekercioğlu Y., Zelzele Ö. B., Ülgen M.

Plastik ve Ambalaj Teknolojisi , cilt.67, ss.42-51, 2002 (Hakemli Dergi)

16. İlaçların ve diğer kimyasalların metabolizması

Ülgen M.

Kimya Teknolojileri , cilt.5, ss.58-60, 2001 (Hakemli Dergi)

17. Nikotin ve günümüzde sigara kullanımı

Bulut M., Oktav M., Ülgen M.

Basev dergisi , cilt.20, ss.25-30, 2000 (Hakemli Dergi)

18. İlaçların eliminasyonuna yardım eden önemli bir mekanizma : İlaç metabolizması

Ülgen M.

Havan dergisi , cilt.2, ss.12-15, 2000 (Hakemli Dergi)

19. Studies on the in vitro hepatic microsomal formation of amides during the metabolism of certain secondary and tertiary benzylic amines.

Ulgen M., Gorrod J.

European journal of drug metabolism and pharmacokinetics , cilt.25, ss.145-50, 2000 (SCI-Expanded, Scopus)

20. Chemical artifacts in drug metabolism research.

Ulgen M.

Bollettino chimico farmaceutico , cilt.138, ss.388-96, 1999 (Hakemli Dergi)

21. The in vitro hepatic microsomal metabolism of 3,5-dimethyl-4-(phenylazo)-(1H)-pyrazole in rats.

Kaymakçioğlu B., Oruç E., Ulgen M., Rollas S.

Drug metabolism and drug interactions , cilt.15, ss.107-14, 1999 (Hakemli Dergi)

22. The in vitro hepatic microsomal metabolism of methyl 2-(2(3H)-benzoxazolone-3-yl)acetate in rats.

Ulgen M., Yilmaz F., Doğruer D., Sahin M.

Drug metabolism and drug interactions , cilt.15, ss.173-9, 1999 (Hakemli Dergi)

23. In vitro metabolic fate of N-substituted Dibenzylamines : Investigation of Biological Oxidation Site on Nitrogen Compounds with Different pKa

Küçükgüzel İ., Ülgen M.

Istanbul Journal of Pharmacy , cilt.32, ss.69-86, 1998 (Scopus)

24. Synthesis and in vitro microsomal metabolism of 4-ethyl-5-(4-fluorophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione and its potential metabolites.

Gülerman N., Rollas S., Ulgen M.

Bollettino chimico farmaceutico , cilt.137, ss.140-3, 1998 (Hakemli Dergi)

25. In vitro microsomal metabolism of some N-benzyl substituted tertiary amines in the rat

Yılmaz F., Ülgen M.

Acta Pharmaceutica Turcica , cilt.4, ss.171-180, 1997 (Scopus)

26. Metabolism of (-)-(S)-nicotine by guinea pig and rat brain: identification of cotinine.

Jacob P., Ulgen M., Gorrod J.

European journal of drug metabolism and pharmacokinetics , cilt.22, ss.391-4, 1997 (SCI-Expanded, Scopus)

27. The in vitro metabolism of norcotinine and related biotransformation products by microsomal preparations.

Eldirdiri N., Ulgen M., Jacob P., Gorrod J.

European journal of drug metabolism and pharmacokinetics , cilt.22, ss.385-90, 1997 (SCI-Expanded, Scopus)

28. In vitro microsomal metabolism of N,N-dibenzylmethylamine, N,N-dibenzyl-4-nitro and N,N-dibenzyl-2,4-dichlorobenzylamine

Ünsalan S., Ülgen M.

FABAD Journal of Pharmaceutical Sciences , cilt.22, ss.103-109, 1997 (Scopus)

29. The in vitro hepatic microsomal metabolism of benzoic acid benzylidenehydrazide.

Ulgen M., Durgun B., Rollas S., Gorrod J.

Drug metabolism and drug interactions , cilt.13, ss.285-94, 1997 (Hakemli Dergi)

30. Microsomal metabolism of N-benzyl-N-ethylaniline and N-benzyl-N-ethyl-p-toluidine.

Ulgen M., Ozer U., Kucukguzel I., Gorrod J.

Drug metabolism and drug interactions , cilt.14, ss.83-98, 1997 (Hakemli Dergi)

31. In vitro metabolic N- and C-oxidation of phenanthridine

Tunç N., Yilmaz F., Ulgen M., Gorrod J.

European Journal of Drug Metabolism and Pharmacokinetics , cilt.22, sa.4, ss.345-349, 1997 (SCI-Expanded, Scopus)

32. The failure of substrate pKa to influence the microsomal formation of amides from N-benzylamines: the microsomal metabolism of N-benzyl pyrrolidine, N-benzyl carbazole and N-acetyl-N-benzyl-4-methylaniline.

Ulgen M., Gorrod J.

The Journal of pharmacy and pharmacology , cilt.48, ss.1320-6, 1996 (SCI-Expanded, Scopus)

33. Evaluation of some arylhydrazones of p-aminobenzoic acid hydrazide as antimicrobial agents and their in vitro hepatic microsomal metabolism.

Komurcu S., Rollas S., Ulgen M., Gorrod J., Cevikbas A.

Bollettino chimico farmaceutico , cilt.134, ss.375-9, 1995 (Hakemli Dergi)

34. Chemical and metabolic studies on N-benzyl-tert-butylamine and its potential metabolites.

Ulgen M., Yilmaz F., Unsalan S., Gorrod J.

Drug metabolism and drug interactions , cilt.12, ss.131-43, 1995 (Hakemli Dergi)

35. Synthesis of some substituted 1,3,4-thiadiazole derivatives

Ülgen M., Gülerman N., Rollas S.

Marmara Pharmaceutical Journal , cilt.10, ss.11-16, 1994 (Scopus)

36. Characterization of N-benzylcarbazole and its metabolites from microsomal mixtures by tandem mass spectrometry.

Ulgen M., Kajbaf M., Lamb J., Jahanshahi M., Gorrod J., Naylor S.

European journal of drug metabolism and pharmacokinetics , cilt.19, ss.343-8, 1994 (SCI-Expanded, Scopus)

37. Structure-activity relationships in the formation of amides from substituted N-benzylanilines.

Ulgen M., Gorrod J., Barlow D.

Xenobiotica; the fate of foreign compounds in biological systems , cilt.24, ss.735-48, 1994 (SCI-Expanded, Scopus)

38. The recognition of a diarylimine as a metabonate produced during incubation of N-benzyl-4-chloroaniline with hepatic microsomal preparations.

Low C., Ulgen M., Gorrod J.

The Journal of pharmacy and pharmacology , cilt.46, ss.585-90, 1994 (SCI-Expanded, Scopus)

39. Sythesis and characterizations of some thiourea derivatives from 1 2 4 triazoline 3 thioures

Küçükgüzel İ., Rollas S., Ülgen M.

Marmara Pharmaceutical Journal , cilt.10, ss.17-25, 1994 (Scopus)

40. Synthesis, isolation and characterisation of some substituted N-benzyl and N-benzoylanilines

Ülgen M., Gorrod J. W.

Istanbul Journal of Pharmacy , cilt.30, ss.1-9, 1994 (Hakemli Dergi)

41. Metabolic and chemical studies on alpha,N-diarylnitrones.

Ulgen M., Gorrod J.

Drug metabolism and drug interactions , cilt.11, ss.245-57, 1994 (Hakemli Dergi)

42. Metabolic N-oxidation of diarylimines: a new metabolic reaction of potential toxicological significance.

Gorrod J., Ulgen M.

Drug metabolism reviews , cilt.26, ss.241-52, 1994 (SCI-Expanded, Scopus)

43. İn vitro Oksidatif Mikrozomal 1.faz İlaç Metabolizması Teknikleri

Ülgen M.

Marmara Pharmaceutical Journal , cilt.9, ss.165-185, 1993 (Scopus)

44. Microsomal formation of N-benzyl-4-hydroxymethylaniline from N-benzyl-4-methylaniline.

Ulgen M., Gorrod J.

The Journal of pharmacy and pharmacology , cilt.44, ss.865-6, 1992 (SCI-Expanded, Scopus)

45. Synthesis,characterization and chromatographic studies on some substituted alpha,N-diphenylnitrones

Ülgen M., Gorrod J. W.

Marmara Pharmaceutical Journal , cilt.8, ss.135-143, 1992 (Scopus)

46. Synthesis and characterization of some new 2,4,6-trisubstituted N,N-dibenzylanilines

Ülgen M., John William G.

Marmara Pharmaceutical Journal , cilt.7, ss.25-32, 1991 (Scopus)

47. Some 1,3,4-oxadiazoline derivatives prepared by starting from benzylic acid hydrazide aryl hydrazones and their antimicrobial evaluation.

Büyüktimkin S., Rollas S., Ulgen M., Otük G.

Die Pharmazie , cilt.45, ss.865, 1990 (SCI-Expanded, Scopus)

48. Şilomikron ve Şilomikron Artık Metabolizması

Ülgen M., Güldür T., Ulutin T.

Endokrinolojide yönelişler , cilt.2, ss.19-21, 1990 (Hakemli Dergi)

49. Synthesis and spectrometric analysis of some new azopyrazole substituted 1,2,4-triazole-5-thiones

Ülgen M., Rollas S., Doğan N., Özger Y.

Marmara Pharmaceutical Journal , cilt.6, ss.41-47, 1990 (Scopus)

50. The assay of some sedative drugs by high pressure liquid chromatography

Ülgen M., Yars U.

Marmara Pharmaceutical Journal , cilt.4, ss.53-61, 1988 (Scopus)

51. Evaluation of some arylhydrazones of N2-arylidenebenzylic acid hydrazide as antimicrobial agents.

Rollas S., Büyüktimkin S., Büyüktimkin N., Ulgen M., Yemni E.

Die Pharmazie , cilt.43, ss.511, 1988 (SCI-Expanded, Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 19

1. İZONİYAZİT HİDRAZON BİLEŞİKLERİNİN İN VİTRO MİKROZOMAL METABOLİZMA ÇALIŞMASI İLE N-OKSİT METABOLİTLERİNİN İNCELENMESİ

Algın E. G., KARAKOÇ J. C., TÜRK B., COŞKUN G. P., ÜLGEN M.

6. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022, ss.261-276, (Tam Metin Bildiri)

2. İBUPROFEN İLE SÜLFONAMİT KOMBİNASYONUYLA OLUŞTURULAN KARŞILIKLI ÖN İLAÇLARIN (CO-DRUG) İN VİTRO MİKROZOMAL METABOLİZMA ÇALIŞMALARI

Çetin M., KARAKOÇ J. C., TÜRK B., COŞKUN G. P., ÜLGEN M.

6. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022, ss.277-282, (Tam Metin Bildiri)

19. The In Vitro Hepatic Metabolism of 1-Phenyl-2-(2-Benzothiazolinone-3-yl)ethanone and ()-1-Phenyl-2-(2-Benzothiazolinone-3-yl)ethanol

ÜLGEN M., YILMAZ F., DOĞRUER D. S., ÇAKIR B., ŞAHİN M. F.

16th European Workshop on Drug Metabolism, Copenhagen, Danimarka, 21 - 26 Haziran 1998

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