Doç. Dr. GÜLEN MELİKE DEMİRBOLAT

Yayın Ağı

Makaleler 28

1. TRAIL-PEG-Apt-PLGA nanosystem as an aptamer-targeted drug delivery system potential for triple-negative breast cancer therapy using in vivo mouse model

DEMİRBOLAT G. M., Kucuk A., Erdogan O., Ozer S., Kozan B., Cuceli T., et al.

Molecular Oncology , 2026 (SCI-Expanded, Scopus)

2. Antitumor Activity of All-Trans Retinoic Acid and Curcumin-Loaded BSA Nanoparticles Against U87 Glioblastoma Cells

Sonmez C., Baltacioglu A., Coskun J., DEMİRBOLAT G. M., GÖK ÖZATAY Ö., ÖZPINAR A.

LIFE-BASEL , cilt.16, sa.1, 2026 (SCI-Expanded, Scopus)

3. pH-triggered liposomal strategy for cisplatin in lung cancer therapy

DEMİRBOLAT G. M., Cakirli E., Saglam A. B., SARIGÜL ÖZBEK S., Abas B. I., Cevik O.

Scientific Reports , cilt.15, sa.1, 2025 (SCI-Expanded, Scopus)

4. An Experimental Design Approach for Producing Curcumin-Loaded Solid Lipid Nanoparticles

Saka O. M., Aygüler C. I., Sevinç Özdemir N., Sürücü B., Çakirli E., Nemutlu E., et al.

PHARMACEUTICALS , cilt.18, sa.4, ss.1-20, 2025 (SCI-Expanded, Scopus)

5. Lab-on-a-chip system for small extracellular vesicle isolation and drug loading for small extracellular vesicle-mediated drug delivery for treatment of cancer patients

Ozcelik A., DEMİRBOLAT G. M., Erdogan O., Kozan B., AKKOYUN F., Cevik E., et al.

EMERGENT MATERIALS , cilt.8, sa.2, ss.1153-1169, 2025 (ESCI, Scopus)

6. Synthesis, characterization, and anticarcinogenic potent of green-synthesized zinc oxide nanoparticles via Citrus aurantium aqueous peel extract

Erdogan O., Pasa S., DEMİRBOLAT G. M., Birtekocak F., Abbak M., Cevik O.

INORGANIC AND NANO-METAL CHEMISTRY , cilt.55, sa.1, ss.67-75, 2025 (SCI-Expanded, Scopus)

7. Effect of platelet exosomes loaded with doxorubicin as a targeted therapy on triple-negative breast cancer cells

Uslu D., Abas B. I., DEMİRBOLAT G. M., Cevik O.

MOLECULAR DIVERSITY , cilt.28, sa.2, ss.449-460, 2024 (SCI-Expanded, Scopus)

8. In vitro hepatotoxicity evaluation of methotrexate-loaded niosome formulation: fabrication, characterization and cell culture studies

Ergin A. D., Oltulu Ç., Türker N. P., Demirbolat G. M.

TURKISH JOURNAL OF MEDICAL SCIENCES , cilt.53, sa.4, ss.872-882, 2023 (SCI-Expanded, Scopus, TRDizin)

9. Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in HeLa cells by enhancing the lysosomotropic effect

Erdogan O., DEMİRBOLAT G. M., Cevik O.

BIOCELL , cilt.47, sa.5, ss.1051-1063, 2023 (SCI-Expanded, Scopus)

10. New Approach to Formulate Methotrexate-Loaded Niosomes: In Vitro Characterization and Cellular Effectiveness

Demirbolat G. M., Aktas E., COŞKUN G. P., ERDOĞAN Ö., ÇEVİK Ö.

JOURNAL OF PHARMACEUTICAL INNOVATION , cilt.17, sa.3, ss.622-637, 2022 (SCI-Expanded, Scopus)

11. Development of a New Drug Delivery System from HELA-Derived Exosomes and the Effect of Docetaxel-Loaded Exosomes on Mitochondrial Apoptosis

Cenik M., Abas B. I., Kocabiyik B., Demirbolat G. M., Cevik O.

JOURNAL OF PHARMACEUTICAL INNOVATION , cilt.17, sa.3, ss.931-939, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

12. Wharton jelly-derived mesenchymal stem cell exosomes induce apoptosis and suppress EMT signaling in cervical cancer cells as an effective drug carrier system of paclitaxel

Abas B. I., DEMİRBOLAT G. M., Cevik O.

PLOS ONE , cilt.17, sa.9, 2022 (SCI-Expanded, Scopus)

13. Development and validation of an HPLC method for simultaneous determination of imatinib mesylate and rifampicin

COŞKUN G. P., DEMİRBOLAT G. M.

JOURNAL OF RESEARCH IN PHARMACY , cilt.26, sa.5, ss.1443-1452, 2022 (ESCI, Scopus, TRDizin)

14. Nanodesigning of multifunctional quantum dots and nanoparticles for the treatment of fibrosarcoma

Demirbolat G. M., Altintas L., Yilmaz S., Arsoy T., Sözmen M., Degim I. T.

JOURNAL OF MICROENCAPSULATION , cilt.39, sa.3, ss.210-225, 2022 (SCI-Expanded, Scopus)

15. PEG4000 modified liposomes enhance the solubility of quercetin and improve the liposome functionality: in vitro characterization and the cellular efficacy

DEMİRBOLAT G. M., Erdogan O., COŞKUN G. P., Cevik O.

TURKISH JOURNAL OF CHEMISTRY , sa.4, ss.1011-1023, 2022 (SCI-Expanded, Scopus, TRDizin)

16. Long chain fatty acids can form aggregates and affect the membrane integrity

Demirbolat G. M., COŞKUN G. P., ERDOĞAN Ö., ÇEVİK Ö.

COLLOIDS AND SURFACES B-BIOINTERFACES , cilt.204, 2021 (SCI-Expanded, Scopus)

17. Electrospun Nanofibers for Dual and Local Delivery of Neuroprotective Drugs

Haidar M. K., TİMUR S. S., Demirbolat G. M., NEMUTLU E., GÜRSOY R. N., ULUBAYRAM K., et al.

FIBERS AND POLYMERS , cilt.22, sa.2, ss.334-344, 2021 (SCI-Expanded, Scopus)

18. TRAIL conjugated silver nanoparticle synthesis, characterization and therapeutic effects on HT-29 colon cancer cells

Birtekocak F., Demirbolat G. M., Cevik O.

Iranian Journal of Pharmaceutical Research , cilt.20, sa.2, ss.45-56, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

19. Treatment of glioblastoma by photodynamic therapy with the aid of synthesized silver nanoparticles by green chemistry from Citrus aurantium

ERDOĞAN Ö., ABBAK M., DEMİRBOLAT G. M., AKSEL M., PAŞA S., DÖNMEZ YALÇIN G., et al.

JOURNAL OF RESEARCH IN PHARMACY , cilt.25, sa.5, ss.641-652, 2021 (Hakemli Dergi)

20. Green biosynthesis, characterization, and cytotoxic effect of magnetic iron nanoparticles using Brassica Oleracea var capitata sub var rubra (red cabbage) aqueous peel extract

Erdogan O., Pasa S., Demirbolat G. M., Cevik O.

TURKISH JOURNAL OF CHEMISTRY , cilt.45, sa.4, ss.1086-1096, 2021 (SCI-Expanded, Scopus)

21. The role of ointment base on stability of dexketoprofen trometamol in ointments

Demirbolat G. M., Demirel A.

JOURNAL OF RESEARCH IN PHARMACY , cilt.25, sa.5, ss.681-688, 2021 (Hakemli Dergi)

22. EVALUATION OF SUSTAINED RELEASE FROM FLUORIDE-LOADED CARBON NANOTUBES

Varol S. E., Bodur H., Demirbolat G. M., Degim I. T.

FLUORIDE , cilt.53, sa.4, ss.643-656, 2020 (SCI-Expanded, Scopus)

23. Atorvastatin-loaded nanosprayed chitosan nanoparticles for peripheral nerve injury

Haidar M. K., Demirbolat G. M., TİMUR S. S., GÜRSOY R. N., NEMUTLU E., ULUBAYRAM K., et al.

BIOINSPIRED BIOMIMETIC AND NANOBIOMATERIALS , cilt.9, sa.2, ss.74-84, 2020 (SCI-Expanded, Scopus)

24. Green synthesis of silver nanoparticles via Cynara scolymus leaf extracts: The characterization, anticancer potential with photodynamic therapy in MCF7 cells

Erdogan O., Abbak M., Demirbolat G. M., Birtekocak F., Aksel M., Pasa S., et al.

PLOS ONE , cilt.14, sa.6, 2019 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

25. Development of chitosan microparticles for controlled release of metoprolol tartarate

Yıldız C., Demirbolat G. M., Ergül M.

Cumhuriyet Medical Journal , cilt.40, sa.4, ss.334-345, 2018 (Hakemli Dergi)

26. Development of Orally Applicable, Combinatorial Drug-Loaded Nanoparticles for the Treatment of Fibrosarcoma

Demirbolat G. M., ALTINTAŞ L., Yilmaz S., Degim I. T.

JOURNAL OF PHARMACEUTICAL SCIENCES , cilt.107, sa.5, ss.1398-1407, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

27. Determination of imatinib mesylate and erlotinib hydrochloride in mice plasma using ultrahigh performance liquid chromatography method

Demir G. M., Degim I. T.

KUWAIT JOURNAL OF SCIENCE , cilt.45, sa.3, ss.57-63, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

28. Preparation of Chitosan Nanoparticles by NanoSpray Drying Technology

DEMİR G. M., DEĞİM İ. T.

FABAD JOURNAL OF PHARMACEUTICAL SCIENCES , cilt.38, sa.3, ss.127-133, 2016 (Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 29

1. Tamoksifen Yüklü Lipit Nanopartüküllerin Meme Kanseri İndüklenmiş Fareler Üzerindeki Etkilerinin İncelenmesi: Morfolojik Değerlendirme

Kosif G., Açıkel Elmas M., Özgün G., Günbay Ş., Özer S., Sarıgül Özbek S., et al.

27. ULUSAL ELEKTRON MİKROKOPİ KONGRESİ, İstanbul, Türkiye, 25 - 27 Eylül 2025, ss.165, (Özet Bildiri)

2. Anti-Cancer Effects of Curcumin and ATRA Investigated By LC-MS/MS Method

Sönmez C., Ergün B., Baltacıoğlu A., Demirbolat G. M., Gök Özatay Ö., Özpınar A.

TuPA International Proteomics Congress, İstanbul, Türkiye, 18 - 19 Eylül 2025, ss.1, (Özet Bildiri)

3. Anti-cancer effects of ATRA and curcumin combination therapy in a glioblastoma cell line

Sönmez C., Baltacıoğlu A., Demirbolat G. M., Gök Özatay Ö., Özpınar A.

FEBS Open Bio, İstanbul, Türkiye, 5 Temmuz - 09 Eylül 2025, cilt.15, ss.305, (Özet Bildiri)

4. The Production and Characteristics of Solid Lipid Nanoparticles

Günbay Ş., Demirbolat G. M., Sarıgül Özbek S.

21st International Pharmaceutical Technology Symposium, Antalya, Türkiye, 9 - 11 Eylül 2024, ss.312-313, (Tam Metin Bildiri)

5. Chemosensitive Evaluation of Methotrexate Loaded Niosomes on Burkitt Lymphoma Cells

DEMİRBOLAT G. M., Ergül M.

13th International Symposium on Pharmaceutical Sciences (ISOPS), 22 - 25 Haziran 2021, (Tam Metin Bildiri)

6. Investigation of some Parameters Affecting the Niosome Formation

DEMİRBOLAT G. M., Yedikaya Ö.

4th International Erciyes Scientific Researches Conference, 16 - 17 Ekim 2020, (Tam Metin Bildiri)

7. INVESTIGATION OF DISSOLUTION PROFILE OF COMMERCIAL MEBEVERINE HYDROCHLORIDE SUGAR COATED TABLET AND CAPSULE

DEMİRBOLAT G. M., AKYOL F.

Çukurova 5th International Scientific Researches Conference, 9 - 11 Ekim 2020, (Tam Metin Bildiri)

8. Cellular Activities of Erlotinib Containing Nanotailored ZnO Quantum Dots

DEMİRBOLAT G. M., ALTINTAŞ L., YILMAZ Ş., ARSOY T., ÇAMLIK G., DEĞİM İ. T.

BIO TURKİYE-ULUSLARARASI BİYOTEKNOLOJİ KONGRESİ, 5 - 07 Mart 2020

9. Introducing Boron Nitride Nanotubes to Drug Delivery Platform for The Treatment of Cancer

TUNA S., DEMİRBOLAT G. M., ÇOBAN Ö., ALTINTAŞ L., YILMAZ Ş., ARSOY T., et al.

BIO TURKİYE-ULUSLARARASI BİYOTEKNOLOJİ KONGRESİ, 5 - 07 Mart 2020

10. Bakır Oksit Nanopartiküllerinin Enginar Yaprağı (Cynara scolymus) Sulu Ekstraktı İle Yeşil Sentezi, Karakterizasyonu, Anti-Bakteriyel ve Sitotoksik Etkileri

ERDOĞAN Ö., ABBAK M., ORYAŞIN E., DEMİRBOLAT G. M., ÇEVİK Ö.

2. Uluslararası Tarım, Çevre ve Sağlık Kongresi, Türkiye, 18 - 19 Ekim 2019, ss.1023-1033, (Tam Metin Bildiri)

11. PREPARATION OF IMATINIB MESILATE LOADED BIOADHESIVE MICROSPHERES IN GASTROINTESTINAL STROMAL TUMOR TREATMENT

Aktaş E., DEMİRBOLAT G. M.

I. International Cancer Days, 19 Eylül 2019, (Tam Metin Bildiri)

12. THE COMBINATION OF ERLOTINIBHYDROCHLORIDE AND DEXKETOPROFEN TROMETAMOL IN CHITOSAN NANOPARTICLESFOR THE CANCER TREATMENT: IN VIVO INVESTIGATION

DEMİRBOLAT G. M., ALTINTAŞ L., yılmaz ş., DEĞİM İ. T.

19th International Pharmaceutical TechnologySymposium-IPTS 2018, 17 - 19 Eylül 2018

13. Application of A Novel Polymeric Electrospun Nanocomposite Incorporating Neuroprotective Drugs In Rat Sciatic Nerve Injury Model

Haidar M. K., DOĞAN S. S., GÜRSOY R. N., NEMUTLU E., DEMİRBOLAT G. M., ULUBAYRAM K., et al.

19th International Pharmaceutical Technology Symposium-IPTS 2018, 17 - 19 Eylül 2018, (Tam Metin Bildiri)

14. Development of Novel Polymeric Nanofibrous Composite Containing Nanoparticles For Dual And Localized Neuroprotective Drug Delivery

Haidar M. K., DOĞAN S. S., GÜRSOY R. N., NEMUTLU E., DEMİRBOLAT G. M., ULUBAYRAM K., et al.

19th International Pharmaceutical Technology Symposium-IPTS 2018, 17 - 19 Eylül 2018, (Tam Metin Bildiri)

15. In Vitro Cytotoxicity Study of Chitosan Nanoparticles Containing Atorvastatin Calcium For Treatment Of Peripheral Nerve Injury

Haidar M. K., DOĞAN S. S., GÜRSOY R. N., NEMUTLU E., DEMİRBOLAT G. M., ULUBAYRAM K., et al.

19th International Pharmaceutical Technology Symposium-IPTS 2018, 17 - 19 Eylül 2018, (Tam Metin Bildiri)

16. Spectrophotometric Determination of Metoprolol Tartarate in Model Solutions Used For Formulation Development

YILDIZ C., DEMİRBOLAT G. M.

International Trace Analysis Congress, 20 - 23 Haziran 2018, (Özet Bildiri)

17. A Validated Method For Determination of Mebeverine Hydrochloride in Tablet And Capsule Dosage Forms by UV Spectroscopy

AKYOL F., DEMİRBOLAT G. M.

INTERNATİONAL TRACE ANALYSIS CONGRESS, 20 - 23 Haziran 2018, (Özet Bildiri)

18. Investigation on Solubility and Permeability Behaviour of Mebeverine Hydrochloride

DEMİRBOLAT G. M., AKYOL F.

European Federation for Pharmaceutical Sciences (EUFEPS) Annual Meeting, 24 - 26 Mayıs 2018, (Tam Metin Bildiri)

19. The Use of Combination Drugs for the Cancer Treatment with Targeted Nanosized Delivery Systems. , 12-15 November 2017, San Diego, USA.

DEMİRBOLAT G. M., ALTINTAŞ L., Yılmaz Ş., DEĞİM İ. T.

AAPS Annual Meeting and Exposition, San Diego, Amerika Birleşik Devletleri, 12 - 15 Kasım 2017, (Tam Metin Bildiri)

20. Effect of Paclitaxel Loaded Chitosan Nanoparticles and Quantum Dots on Breast Cancer

DEMİRBOLAT G. M., İLHAN M., AKKOL E., TAŞTAN H., IŞIK A., DEĞİM İ. T.

2nd International Conference on Natural Products for Cancer Prevention, Kayseri, Türkiye, 8 - 11 Kasım 2017, (Özet Bildiri)

21. PREPARATION AND INVESTIGATION ON ERLOTINIB HCL ANDDEXKETOPROFEN TREMETAMOL LOADED CHITOSANNANOPARTICLES FOR CANCER TREATMENT

DEMİRBOLAT G. M., ALTINTAŞ L., YILMAZ Ş., DEĞİM İ. T.

2nd International Gazi PharmaSymposium Series (GPSS-2017), 11 - 13 Ekim 2017, (Tam Metin Bildiri)

22. Drug delivery for neuroprotection: Opportunuties and challenges

EROĞLU H., Türkoğlu Ö. F., SARGON M. F., Haidar M. K., DEMİRBOLAT G. M., ÖZTÜRK Ş., et al.

3rd International Multidisciplinary Symposium on Drug Research and Development, 5 - 07 Ekim 2017, (Özet Bildiri)

23. Drug delivery applications for neuroprotection: Nanoparticles, nanofibers, microparticles

EROĞLU H., Türkoğlu Ö. F., SARGON M. F., Haidar M. K., DEMİRBOLAT G. M., ÖZTÜRK Ş., et al.

3rd International Congress of the Greek Local Chapter of the Controlled Release Society, 19 - 20 Haziran 2017, (Özet Bildiri)

24. Formulation of atorvastatin calcium loaded chitosan nanoparticles by nano-spray drying method for sustained drug delivery

Haidar M. K., DEMİRBOLAT G. M., NEMUTLU E., ULUBAYRAM K., ÖNER L., EROĞLU H.

3rd International Congress of the Greek Local Chapter of the Controlled Release Society, 19 - 20 Haziran 2017, (Özet Bildiri)

25. Preparation of Chitosan Nanoparticles by Nano Spray Drying Technology

DEMİR G. M., DEĞİM İ. T.

International Gazi Pharma Symposium Series (GPSS), 12 - 15 Kasım 2015, (Tam Metin Bildiri)

26. Development of a Nanocarrier Sytem containing Combination of Drugs Erlotinib Dexketoprofen for Effective Anticancer Therapy

DEMİR G. M., ÇOBAN Ö., Sema T. T., DEĞİM Z., DEĞİM İ. T.

American Association of Pharmaceutical Scientists, Orlando, Amerika Birleşik Devletleri, 25 - 29 Ekim 2015, (Tam Metin Bildiri)

27. Simultaneous Determination of Imatinib Mesylate and Dexketoprofen Trometamol Using UPLC

ÇOBAN Ö., DEMİR G. M., Sema T. T., DEĞİM Z., DEĞİM İ. T.

International Symposium on Pharmaceutical Sciences, 9 - 12 Haziran 2015, (Tam Metin Bildiri)

28. Stirring Speed Effects On Physical Characterıstics Of Theophylline Microspheres

DEMİR G. M., KARAKÜÇÜK A. E., Bektaş D., ÇOBAN Ö., Gülpınar E., Tuna Torunoğlu S., et al.

5th International Conference on Nanotechnology: Fundamentals and Applications (ICNFA 2014), 11 - 13 Ağustos 2014, (Tam Metin Bildiri)

29. Dome Matrix (R) Assembled System For Two Pulse Release of Esomeprazole

DEMİR G. M., Tarımcı M. N., Colombo P., Rossi A.

10th International Symposium on Pharmaceutical Sciences (ISOPS-10), 26 - 29 Haziran 2012, (Özet Bildiri)

Kitaplar 2

1. Zeta Potential Determination of Targeted Nanoparticles

Demirbolat G. M., Değim Z., Değim İ. T.

Drug Delivery with Targeted Nanoparticles, Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul, Editör, Jenny Stanford Publishing, Singapore, ss.29-56, 2021

2. Proton Pompa İnhibitörlerinin Farmasötik Dozaj Şekilleri ve İlaç Taşıyıcı Sistemler; Her Yönüyle Proton Pompaları ve Proton Pompa İnhibitörleri

Demirbolat G. M.

Her Yönüyle Proton Pompaları ve Proton Pompa İnhibitörleri, MERVE ERGÜL,HİLMİ ATASEVEN, Editör, Cumhuriyet Üniversitesi Yayınları, Sivas, ss.181-197, 2020

Metrikler

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524

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563

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