Asst. Prof.

Perinur BOZAYKUT EKER


Faculty of Arts and Sciences

Molecular Biology and Genetics

Biography

Dr. Perinur Bozaykut (Eker), lisans eğitimini Marmara Üniversitesi Biyoloji Bölümü’nde tamamladı. Yüksek lisans eğitimine Marmara Üniversitesi, Tıp Fakültesi, Biyokimya alanında devam eden Bozaykut, tez çalışmalarının bir kısmını kazandığı lisans sonrası eğitim bursuyla King’s College London bünyesinde Kalp ve Damar Bölümü’nde gerçekleştirdi. Doktora eğitimini Marmara Üniversitesi’nde tamamladıktan sonra Post-doktora araştırmalarını yürütmek üzere TUBİTAK desteği ile Harvard Medical School Genetik Bölümü’nde görev aldı. Doktora sonrası araştırmalarında, yaşlanmanın genetiği üzerine transkriptomiks bazlı araştırmalara ek olarak ilgili alanda ilaç araştırmalarına dahil oldu. Bu güne kadar yaptığı çalışmaları ile Physiological Society, SFRR-Europe, Türk Biyokimya derneği gibi kurumlardan ödüller kazandı. Devam eden bilimsel çalışmaları; kanser ve yaşlanmanın ilişkisinin genetik, farmakolojik ve beslenme gibi farklı yönlerden araştırılması üzerinedir.

Education Information

2011 - 2015

2011 - 2015

Doctorate

Marmara University, Institute Of Health Sciences, Department Of Biochemistry, Turkey

2009 - 2011

2009 - 2011

Post Graduate

Marmara University, Institute Of Health Sciences, Department Of Biochemistry, Turkey

Dissertations

2015

2015

Doctorate

The Role of Endoplasmic Reticulum Stress and Nrf2 Pathway on High Cholesterol Diet İnduced Atherosclerosis

Marmara University, Institute Of Health Sciences

2011

2011

Post Graduate

Hiperkolesterolemi modelinde lipit birikimi ve aterogenezde rol oynayan faktörlerin aydınlatılması

Marmara University, Institute Of Health Sciences, Department Of Biochemistry

Foreign Languages

C1 Advanced

C1 Advanced

English

Research Areas

Biochemistry, Molecular Biology and Genetics

Academic Titles / Tasks

2019 - Continues

2019 - Continues

Assistant Professor

Acibadem Mehmet Ali Aydinlar University, Faculty of Arts and Sciences, Molecular Biology and Genetics

2016 - 2019

2016 - 2019

Assistant Professor

Istanbul Medipol University, Internatıonal Faculty Of Medıcıne, Department Of Basıc Medıcal Scıences (Medıcıne)

2016 - 2018

2016 - 2018

Researcher

Harvard University, Medical School, Genetics

2015 - 2016

2015 - 2016

Lecturer

Istanbul Medipol University, Internatıonal Faculty Of Medıcıne, Department Of Basıc Medıcal Scıences (Medıcıne)

Managerial Experience

2020 - Continues

2020 - Continues

Ethics Committee Member

Acibadem Mehmet Ali Aydinlar University, Faculty of Arts and Sciences, Molecular Biology and Genetics

Courses

Post Graduate

Post Graduate

Molecular and Translational Biomedicine

Under Graduate

Under Graduate

Working Progress

Under Graduate

Under Graduate

General Biology II

Post Graduate

Post Graduate

Research Techniques and Ethics in Natural Sciences

Under Graduate

Under Graduate

Animal models of human pathology

Under Graduate

Under Graduate

Molecular mechanisms of disease

Under Graduate

Under Graduate

General Biology I

Post Graduate

Post Graduate

Introduction to Molecular and Translational Biomedicine

Under Graduate

Under Graduate

Biochemistry

Post Graduate

Post Graduate

Hücre Biyolojisi ve Biyokimya

Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes

2019

2019

Aging and Cardiovascular Diseases: The Role of Cellular Senescence

BOZAYKUT EKER P.

OXIDATIVE STRESS IN HEART DISEASES, pp.207-233, 2019 (Journal Indexed in SCI) identifier

2016

2016

Endoplasmic reticulum stress related molecular mechanisms in nonalcoholic steatohepatitis

Bozaykut P. , ŞAHİN A., Karademir B., Ozer N. K.

MECHANISMS OF AGEING AND DEVELOPMENT, vol.157, pp.17-29, 2016 (Journal Indexed in SCI) identifier identifier identifier

2014

2014

Regulation of protein turnover by heat shock proteins

Bozaykut P. , Ozer N. K. , Karademir B.

FREE RADICAL BIOLOGY AND MEDICINE, vol.77, pp.195-209, 2014 (Journal Indexed in SCI) identifier identifier identifier

2014

2014

Heat shock proteins and proteasomal degradation in normal and tumor cells

Betul K., Perinur B. , Nesrin K. O.

FREE RADICAL BIOLOGY AND MEDICINE, vol.75, 2014 (Journal Indexed in SCI) identifier identifier

2014

2014

The effect of Irisin on antioxidant system in liver

BATIREL S., Bozaykut P. , Altundag E. M. , Ozer N. K. , Mantzoros C. S.

FREE RADICAL BIOLOGY AND MEDICINE, vol.75, 2014 (Journal Indexed in SCI) identifier identifier

2013

2013

Regulation of protein turnover by heat shock proteins

Karademir B., Sozen E., Bozaykut P. , Ece A., Ozaltin E., Ozer N. K. , et al.

FREE RADICAL BIOLOGY AND MEDICINE, vol.65, 2013 (Journal Indexed in SCI) identifier

2013

2013

The role of heat stress on the age related protein carbonylation

Bozaykut P. , Sozen E., Kaga E., Ece A., Ozaltin E., Ek B., et al.

JOURNAL OF PROTEOMICS, vol.89, pp.238-254, 2013 (Journal Indexed in SCI) identifier identifier identifier

2012

2012

The role of heat shock proteins in the protein oxidation during aging

Catalgol B., Sozen E., Bozaykut P. , Kaga E., Ozer N. K. , Grune T.

FREE RADICAL BIOLOGY AND MEDICINE, vol.53, 2012 (Journal Indexed in SCI) identifier

2011

2011

Age-related loss of stress-induced nuclear proteasome activation is due to low PARP-1 activity

Bakondi E., Catalgol B., Bak I., Jung T., Bozaykut P. , Bayramicli M., et al.

FREE RADICAL BIOLOGY AND MEDICINE, vol.50, no.1, pp.86-92, 2011 (Journal Indexed in SCI) identifier identifier identifier

Articles Published in Other Journals

2021

2021

Cellular stress responses of long-lived and cancer-resistant naked mole-rats

Bozaykut Eker P.

e-Türk Biyokimya Dergisi (elektronik), vol.46, no.2, pp.1-8, 2021 (Other Refereed National Journals)

Refereed Congress / Symposium Publications in Proceedings

2020

2020

Hypoxia-related mechanisms in cancer resistant animal models

Bozaykut Eker P.

9th International Molecular Biology and Biotechnology Congress, 6 - 10 December 2020, pp.54

2020

2020

Identification of new anti-aging drugs by drug repurposing and their experimental validation by barcode-based RNA sequencing

Bozaykut Eker P.

V. Türkiye in vitro Diyagnostik Sempozyumu, Sağlık Biyoteknolojisi, İzmir, Turkey, 19 - 21 February 2020, pp.10

2018

2018

High-throughput analysis of high-cholesterol diet induced atherosclerosis and the effect of endoplasmic reticulum stress

Bozaykut P.

III. Turkey in vitro Diagnostic (IVD) Symposium, İzmir, Turkey, 28 February - 02 March 2018, vol.43, no.1, pp.22-23

2016

2016

Proteasomal system and heat shock proteins in cancer cell death mechanisms

Karademir B., Yılmaz A. M. , Altundag E. M. , Sozen E., Bozaykut Eker P. , Ozer N. K.

1st International Cell Death Research Congress, İstanbul, Turkey, 4 - 08 May 2016, pp.1

2015

2015

Unfolded protein response to the hypercholesterolemia induced endoplasmic reticulum stress in atherosclerosis

Bozaykut P. , Karademir B., Ozer N. K.

40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life, Berlin, Germany, 4 - 09 July 2015, vol.282, pp.111 identifier

2015

2015

Oxidative and Endoplasmic Reticulum Stress Related Molecular Mechanisms in Atherosclerosis

Bozaykut Eker P. , Karademir B., Kartal Özer N.

5th International Congress of Molecular Medicine, İzmir, Turkey, 20 - 22 May 2015, pp.30

2015

2015

Inhibition of Molecular Mechanisms Related to Hyperthermia Induced Thermotolerence

Bozaykut Eker P. , Kartal Özer N., Karademir B.

3rd EACR-Sponsored Anticancer Agent Development Congress, İzmir, Turkey, 18 - 19 May 2015, pp.14

2014

2014

Role of vitamin E on PPARgamma and Nrf2 related signalling pathways in in vivo model of atherosclerosis

Bozaykut P. , Karademir B., Yazgan B., Sozen E., Siow R., Mann G. E. , et al.

FEBS EMBO 2014 Conference, Paris, France, 30 August - 04 September 2014, vol.281, pp.675 identifier

2014

2014

The role of HSP70 in the chemotherapeutic approach for proteasomal degradation and autophagy

Sozen E., Bozaykut Eker P. , Ozer N. K. , Grune T., Karademir B.

17th Biennial Meeting of Society for Free Radical Research International (SFRRI 2014), Kyoto, Japan, 23 May 2014, pp.1

2013

2013

The Effect of Hypercholesterolemia Induced Oxidative Stress on Cardiac Failure and Autophagy Role of Vitamin E

Sözen A. E. , Yazgan B., Karademir B., Bozaykut Eker P. , Kaga E., Ozer N. K.

FEBS Special Meeting on Protein Quality Control and Ubiquitin Systems in Health and Disease, Aydın, Turkey, 14 - 16 November 2013, pp.78

2013

2013

Different response of proteasomal degradation in normal and tumor cells during heat stress

Catalgol B., Bozaykut P. , Ozer N. K. , Grune T.

Oxygen Club of California World Congress 2012, Cell Signaling, Gene-Nutrition Interactions, Turin, Italy, 20 June 2013, pp.47

2011

2011

Heat shock proteins in the post translational modifications

Karademir B., Bozaykut P. , Sozen E., Kaga E., Grune T.

SFRR-Europe 2011 Meeting, Redox Biology and Micronutrients: From signaling to translation and back, İstanbul, Turkey, 07 September 2011, pp.54

2010

2010

Expressions of Matrix Metalloproteinases in Atherosclerosis

Bozaykut P. , Catalgol B., Kaga E., Sozen E., Ozer N. K.

35th FEBS Congress Molecules of Life, Gothenburg, Sweden, 26 June 2010, pp.98

2010

2010

The Main Genetic Pathways Playing Roles in Atherosclerosis

Bozaykut P. , Catalgol B., Kaga E., Sozen E., Kartal Özer N.

Protein maintenance and turnover in ageing & diseases, FEBS Advanced Lecture Course, Athens, Greece, 04 June 2010, pp.10

Books & Book Chapters

2019

2019

Aging and Cardiovascular Diseases: The Role of Cellular Senescence

Bozaykut Eker P.

in: Oxidative Stress in Heart Diseases, Chakraborti S,Dhalla N,Ganguly N,Dikshit N, Editor, Springer, Singapore, pp.207-233, 2019

Memberships / Tasks in Scientific Organizations

2011 - Continues

2011 - Continues

The Physiological Society

Member

2011 - Continues

2011 - Continues

Turkish Biochemical Society

Member

2011 - Continues

2011 - Continues

Society of Free Radical Research

Member

Scientific Consultations

2018 - 2018

2018 - 2018

Scientific Consultancy

Eternans Biotechnology

Acibadem Mehmet Ali Aydinlar University, Faculty of Arts and Sciences, Molecular Biology and Genetics, Turkey

Awards

February 2020

February 2020

Sözlü Sunum Ödülü

Türk Biyokimya Derneği

April 2015

April 2015

Young Researcher Scholarship

Mokad

April 2013

April 2013

Asistan Bildiri Yarışması birinciliği

Marmara Üniversitesi

September 2011

September 2011

Early Research Career Award

Sfrr-Europe

July 2011

July 2011

Poster Competition Award

The Physiological Society Uk



Edit Congress and Symposium Activities

2013

2013

Lipid peroxidation by-products in metabolic diseases

Invited Speaker

Yerushalayim-Israel

Scholarships

2017 - 2018

2017 - 2018

Postdoctoral Fellow

Other International Organizations

2016 - 2017

2016 - 2017

2219 Programı

TUBITAK

Citations

Total Citations (WOS): 233

h-index (WOS): 8