Non-lactate strong ion difference: a clearer picture

Gucyetmez B. , Atalan H. K.

JOURNAL OF ANESTHESIA, vol.30, no.3, pp.391-396, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1007/s00540-016-2158-5
  • Title of Journal : JOURNAL OF ANESTHESIA
  • Page Numbers: pp.391-396


The recommended method for elucidating the effects of strong ions other than lactate on acid-base balance is to calculate the non-lactate strong ion difference (SIDnl). A relationship between HCO3 (-) and SIDnl in hyperchloremic patients has already been demonstrated; in the present study, the relationships between SIDnl, the apparent strong ion difference (SIDa), and mortality at intensive care unit (ICU) admission were investigated.