Alteration of the microRNA expression profile in familial Mediterranean fever patients


Akkaya-Ulum Y. Z. , Balci-Peynircioglu B., Karadag O., Eroglu F. K. , Kalyoncu U., Kiraz S., ...More

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, vol.35, no.6, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2017
  • Title of Journal : CLINICAL AND EXPERIMENTAL RHEUMATOLOGY

Abstract

Objective. Phenotypic heterogeneity in familial Mediterranean fever (FMF) disease indicated that FMF is not a simple monogenic disease. Therefore it has been suggested that epigenetic factors can be one of the reason for the variations. We undertook this study to test potential involvement of miRNAs in the pathogenesis of FMF.