Is it Possible to Avoid Liver Biopsy in Living Donors for Liver Transplantation by Using Two-Dimensional Shear Wave Elastography?

ALTAN KUŞ A., YILDIZ I.

TRANSPLANTATION PROCEEDINGS, cilt.55, sa.2, ss.363-368, 2023 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1016/j.transproceed.2023.01.007
  • Dergi Adı: TRANSPLANTATION PROCEEDINGS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.363-368
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Purpose. The present study aims to evaluate the correlation of two-dimensional shear wave elastography results with histopathological findings performed simultaneously with liver biopsy (LB) in healthy liver transplant donors.Methods. A total of 53 living donors, 35 male and 18 female, were included in this prospective, observational, single-center study.Patients with abnormal liver function tests were not included in our study. Hepatosteatosis, fibrosis, and inflammation were evaluated with the FattyResults. The mean age of the donors was 33.04 +/- 9.07 years and the mean body mass index was 23.41 +/- 6.23 kg/m2. The mean elastography kilo pascal (kPA) value of all donors was determined as 6.03 +/- 2.32 kPa. The mean LB activity scores of the donors were found to be 1.64 +/- 1.18 and ranged from 0 to 5. There was no significant correlation between elastography kPa value and pathologic activity score, steatosis score, balloon degeneration, and inflammationConclusion. Shear wave elastography measurements showed that the predictive power of pathologic findings in donor LB was not sufficient.