Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific RT-PCR assay for human glandular kallikrein


Shariat S., Kattan M., Erdamar S. , Nguyen C., Scardino P., Spencer D., ...More

JOURNAL OF CLINICAL ONCOLOGY, vol.21, no.7, pp.1223-1231, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 7
  • Publication Date: 2003
  • Doi Number: 10.1200/jco.2003.08.142
  • Title of Journal : JOURNAL OF CLINICAL ONCOLOGY
  • Page Numbers: pp.1223-1231

Abstract

Purpose: To compare the detection of human glandular kallikrein 2 (hK2) mRNA expression in archival lymph nodes with disease progression, the development of prostate cancer metastases, and mortality in patients undergoing radical prostatectomy for locally advanced nonmetastatic prostate cancer.