Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific RT-PCR assay for human glandular kallikrein

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Shariat S., Kattan M., Erdamar S., Nguyen C., Scardino P., Spencer D., ...More

JOURNAL OF CLINICAL ONCOLOGY, vol.21, no.7, pp.1223-1231, 2003 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 21 Issue: 7
• Publication Date: 2003
• Doi Number: 10.1200/jco.2003.08.142
• Journal Name: JOURNAL OF CLINICAL ONCOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1223-1231
• Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Purpose: To compare the detection of human glandular kallikrein 2 (hK2) mRNA expression in archival lymph nodes with disease progression, the development of prostate cancer metastases, and mortality in patients undergoing radical prostatectomy for locally advanced nonmetastatic prostate cancer.