Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific RT-PCR assay for human glandular kallikrein

Shariat, SF; Kattan, MW; Erdamar, Ayşe; Nguyen, C; Scardino, PT; Spencer, DM; Wheeler, TM; Slawin, KM

doi:10.1200/jco.2003.08.142

Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific RT-PCR assay for human glandular kallikrein

Shariat S., Kattan M., Erdamar S. , Nguyen C., Scardino P., Spencer D., ...More

JOURNAL OF CLINICAL ONCOLOGY, vol.21, no.7, pp.1223-1231, 2003 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 21 Issue: 7
Publication Date: 2003
Doi Number: 10.1200/jco.2003.08.142
Title of Journal : JOURNAL OF CLINICAL ONCOLOGY
Page Numbers: pp.1223-1231

Abstract

Purpose: To compare the detection of human glandular kallikrein 2 (hK2) mRNA expression in archival lymph nodes with disease progression, the development of prostate cancer metastases, and mortality in patients undergoing radical prostatectomy for locally advanced nonmetastatic prostate cancer.