Detection of reactive oxygen metabolites in malignant and adjacent normal tissues of patients with lung cancer.


Okur H. K. , YÜKSEL M., Lacin T., Baysungur V., Okur E.

World journal of surgical oncology, cilt.11, ss.9, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 11
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1186/1477-7819-11-9
  • Dergi Adı: World journal of surgical oncology
  • Sayfa Sayıları: ss.9

Özet

Background: Different types of reactive oxygen metabolites (ROMs) are known to be involved in carcinogenesis. Several studies have emphasized the formation of ROMs in ischemic tissues and in cases of inflammation. The increased amounts of ROMs in tumor tissues can either be because of their causative effects or because they are produced by the tumor itself. Our study aimed to investigate and compare the levels of ROMs in tumor tissue and adjacent lung parenchyma obtained from patients with lung cancer.