Primary Adrenal Lymphoma with Secondary Central Nervous System Involvement: A Case Report and Review of the Literature

Aydin K., Okutur K., Bozkurt M., Aydin O., Namal E., Ozturk A., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.30, sa.4, ss.405-408, 2013 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 30 Konu: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.4274/tjh.2012.0172
  • Sayfa Sayıları: ss.405-408


Approximately 10%-20% of all systemic lymphomas have central nervous system (CNS) involvement, which has been correlated to a worsened prognosis. It is well known that secondary involvement of the adrenal glands may occur in up to 25% of patients during the course of diffuse lymphoma. Primary adrenal lymphoma (PAL), however, is a different entity, and it is defined as the presence of adrenal lymphoma without evidence of either nodal involvement or leukemia. It has been shown that this occurrence is rarely accompanied by extranodal involvement, such as in the CNS. PAL exhibits a tendency for CNS relapse and this possibility should be examined even before symptoms are present. Herein we present a patient with PAL and secondary CNS involvement.