An extremely rare case of a pediatric peripheral primitive neuroectodermal tumour: Orbital primitive neuroectodermal tumour

Creative Commons License

Bal H., Sahin C., ARIBAL M. E.

MARMARA MEDICAL JOURNAL, cilt.26, sa.3, ss.171-173, 2013 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5472/mmj.2013.02639.2
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.171-173
  • Anahtar Kelimeler: Pediatric, Peripheral primitive neuroectodermal tumour, Orbita
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Primitive neuroectodermal tumours (PNETs) are a group of malignant soft tissue tumours of neuroepithelial origin that arise from primitive neural crest cells. Most of the PNETs occur in the central nervous system (CNS). If the origin is outside the CNS it is called peripheral primitive neuroectodermal tumour (pPNET). Histopathologically, PNETs consist of small round cells with a hyperchromatic nuclei, high nuclear- cytoplasmic ratio and varying degrees of neural differentiation detectable by immunohistochemical or ultrastructural techniques. pPNETs occur predominantly in children and young adults and show no gender difference. Occurrences of pPNETs in the orbit are infrequent and to the best of our knowledge only eighteen cases have been reported in the literature up to now. In this study, we present clinic, radiologic and histopathologic features of an orbital mass in an 8-year-old boy, which was diagnosed as a primary orbital pPNET confirmed by immunohistochemistry.