Two Cases with Progressive Cystic Leukoencephalopathy


Yapici Z., Benbir G., Saltik S., He L., Brown G. K. , Taylor R. W. , ...More

NEUROPEDIATRICS, vol.40, no.1, pp.47-51, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1055/s-0029-1225626
  • Title of Journal : NEUROPEDIATRICS
  • Page Numbers: pp.47-51

Abstract

Leukoencephalopathies with cystic changes in the white matter on magnetic resonance imaging are aetiologically heterogeneous neurological disorders seen in children. A group of leukoencephalopathies characterised by white matter lesions progressing to multifocal cystic degeneration has been reported in various disorders, including mitochondrial enzyme deficiencies, leukodystrophies, and infectious processes. We report two patients with leukoencephalopathy showing progressive cystic changes on serial MRI, and magnetic resonance spectroscopy resembling progressive cavitating leukoencephalopathy.