Effects of carbachol on apoptosis in human chronic myelogenous leukemic K562 cell line

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AYDIN OMAY B., Tulunay A., Eksioglu-Demiralp E., KAN B., CABADAK H.

MARMARA MEDICAL JOURNAL, cilt.32, sa.1, ss.38-43, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5472/marumj.518983
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.38-43
  • Anahtar Kelimeler: Muscarinic receptors, K562 cells, Carbachol, Cholinergic system, MUSCARINIC RECEPTORS, CANCER CELLS, GROWTH, PROLIFERATION, ACETYLCHOLINE, PATHWAYS, NICOTINE, ABLATION, DEATH, M-3
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Objectives: Muscarinic receptors mediate diverse actions of acetylcholine in the central nervous system and in non-nervous tissues innervated by the parasympathetic nervous system. Our study aims to evaluate the potential association of the M-3 muscarinic receptor with K562 cell proliferation and death.