Glucagon in the gut - brain axis
JOURNAL OF DIABETOLOGY, 2023 (ESCI)
- Yayın Türü: Makale / Derleme
- Basım Tarihi: 2023
- Doi Numarası: 10.4103/jod.jod_103_23
- Dergi Adı: JOURNAL OF DIABETOLOGY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet
Özet
The intricate relationship between the gut and the brain has long captured the imagination of scientists, philosophers, and clinicians alike. Over the past few decades, research has unveiled a complex and bidirectional communication network that connects these seemingly distinct organs, giving rise to the concept of the gut-brain axis. This axis represents a dynamic and multifaceted system through which the gut and the brain exchange signals, impacting not only digestive processes but also a wide array of physiological and neurological functions. From influencing appetite and mood to playing a role in metabolic regulation, the gut-brain axis has emerged as a crucial nexus in understanding human health and well-being. This chapter delves into the intricate mechanisms that underlie the gut-brain axis, exploring its components and pathways with a special focus on the role played by glucagon. By unraveling the mysteries of this axis, we gain valuable insights into how our body's diverse systems collaborate to maintain a delicate balance and how disturbances within this axis can contribute to a range of health conditions.