Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model

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Eralp Y., Wang X., Wang J., Maughan M., Polo J., Lachman L.

BREAST CANCER RESEARCH, cilt.6, sa.4, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 6 Sayı: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1186/bcr787
  • Dergi Adı: BREAST CANCER RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: adjuvant treatment, breast cancer, chemotherapy, gene vaccines, immunotherapy, METASTATIC BREAST-CANCER, PHASE-I TRIAL, DNA VACCINATION, T-CELLS, PROTECTIVE IMMUNITY, CYTOKINE PRODUCTION, MONOCLONAL-ANTIBODY, ADJUVANT THERAPY, TUMOR VACCINE, FULL-LENGTH
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Introduction: The purpose of the present study was to determine whether cytotoxic chemotherapeutic agents administered prior to immunotherapy with gene vaccines could augment the efficacy of the vaccines.