The -31 G/C promoter gene polymorphism of survivin in Turkish patients with colorectal cancer

BUDAK M., Bozkurt C., ÇETİN S. , TUNCEL H.

CEYLON MEDICAL JOURNAL, vol.63, no.3, pp.151-155, 2018 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.4038/cmj.v63i3.8714
  • Title of Journal : CEYLON MEDICAL JOURNAL
  • Page Numbers: pp.151-155


Introduction Survivin (also known as birc5) is the first protein discovered among the apoptosis-regulating gene family referred to as inhibitor of apoptosis proteins (IAPs). It is expressed and controlled during cellular differentiation and development in human beings. Survivin expression has been shown in a number of cancers and has been associated with cancer development.