Identification of point mutations and large rearrangements in the BRCA1 gene in 667 Turkish unselected ovarian cancer patients


Aktas D., GÜLTEKİN M., Kabacam S., ALİKAŞİFOĞLU M., Turan A. T. , Tulunay G., et al.

GYNECOLOGIC ONCOLOGY, cilt.119, ss.131-135, 2010 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 119 Konu: 1
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.ygyno.2010.05.018
  • Dergi Adı: GYNECOLOGIC ONCOLOGY
  • Sayfa Sayısı: ss.131-135

Özet

Objective. The aim of this study was to evaluate the prevalence and spectrum of a known founder mutation, 5382insC and large genomic rearrangements (LGRs) in BRCA1 in ovarian cancer patients in Turkey. The additional aim was to determine the genetic testing strategy in Turkish breast/ovarian cancer family.