Identification of point mutations and large rearrangements in the BRCA1 gene in 667 Turkish unselected ovarian cancer patients

Aktas D., GÜLTEKİN M., Kabacam S., ALİKAŞİFOĞLU M., Turan A. T. , Tulunay G., ...More

GYNECOLOGIC ONCOLOGY, vol.119, no.1, pp.131-135, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 119 Issue: 1
  • Publication Date: 2010
  • Doi Number: 10.1016/j.ygyno.2010.05.018
  • Title of Journal : GYNECOLOGIC ONCOLOGY
  • Page Numbers: pp.131-135


Objective. The aim of this study was to evaluate the prevalence and spectrum of a known founder mutation, 5382insC and large genomic rearrangements (LGRs) in BRCA1 in ovarian cancer patients in Turkey. The additional aim was to determine the genetic testing strategy in Turkish breast/ovarian cancer family.