Concomitant administration of uracil-tegafur and leucovorin during adjuvant radiotherapy for locally advanced rectal cancer

ATASOY, BESTE; ABACIOGLU, Mehmet; Dane, F.; Ozgen, Z.; Yumuk, P.; Ozden, S.; Akgun, Z.; Mayadagli, A.; BAŞARAN, Gül; Turhal, S.; Sengoz, M.

Concomitant administration of uracil-tegafur and leucovorin during adjuvant radiotherapy for locally advanced rectal cancer

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ATASOY B. M., ABACIOGLU M. U., Dane F., Ozgen Z., Yumuk P. F., Ozden S., ...More

JOURNAL OF BUON, vol.12, no.2, pp.203-208, 2007 (SCI-Expanded)

Publication Type: Article / Article
Volume: 12 Issue: 2
Publication Date: 2007
Journal Name: JOURNAL OF BUON
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.203-208
Keywords: concomitant chemoradiotherapy, oral fluoropyrimidine, rectal cancer, survival, toxicity, UFT, ORAL LEUCOVORIN, PHASE-III, FLUOROURACIL, CHEMOTHERAPY, THERAPY, UFT, MULTICENTER, TRIAL
Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Purpose: We report the feasibility and toxicity profile, and the impact on local control, disease-free survival and overall survival rates of our study which consisted of postoperative concurrent chemoradiotherapy, followed by adjuvant chemotherapy using uracil-tegafur (UFT)/leukovorin (L V) in locally advanced rectal cancer patients.