Bronchial hyperreactivity and airway wall thickening in obstructive sleep apnea patients

Sariman N., Levent E., Cubuk R., Yurtlu S., Aksungar F.

SLEEP AND BREATHING, vol.15, no.3, pp.341-350, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.1007/s11325-010-0387-7
  • Title of Journal : SLEEP AND BREATHING
  • Page Numbers: pp.341-350


Hypoxia/reoxygenation episodes in obstructive sleep apnea (OSA) results in the alteration of the oxidative balance, leading to the development of inflammation. Airway wall thickening and inflammatory changes are suggested as a primary cause of the airway hyperresponsiveness in asthmatics. Bronchial hyperreactivity (BH) may also occur in patients with OSA. We investigated the presence of BH and airway wall thickness in OSA and correlations with inflammatory markers.