Bronchial hyperreactivity and airway wall thickening in obstructive sleep apnea patients

Sariman N., Levent E., Cubuk R., Yurtlu S., Aksungar F.

SLEEP AND BREATHING, cilt.15, sa.3, ss.341-350, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1007/s11325-010-0387-7
  • Dergi Adı: SLEEP AND BREATHING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.341-350
  • Anahtar Kelimeler: Airway wall thickening, Bronchial hyperreactivity, Obstructive sleep apnea, High-resolution computerized tomography, C-REACTIVE PROTEIN, BODY-MASS INDEX, COMPUTED-TOMOGRAPHY, INFLAMMATION, OBESITY, ASTHMA, HYPERRESPONSIVENESS, SENSITIVITY, MARKERS, RISK
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Hypoxia/reoxygenation episodes in obstructive sleep apnea (OSA) results in the alteration of the oxidative balance, leading to the development of inflammation. Airway wall thickening and inflammatory changes are suggested as a primary cause of the airway hyperresponsiveness in asthmatics. Bronchial hyperreactivity (BH) may also occur in patients with OSA. We investigated the presence of BH and airway wall thickness in OSA and correlations with inflammatory markers.