Plasma activity of of thrombin activatable fibrinolysis inhibitor in Crimean-Congo hemorrhagic fever

Sonmez M., Aydin K., Durmus A., Sucu N., Yilmaz M., Akdogan E., ...Daha Fazla

JOURNAL OF INFECTION, cilt.55, sa.2, ss.184-187, 2007 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.jinf.2007.02.010
  • Dergi Adı: JOURNAL OF INFECTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.184-187
  • Anahtar Kelimeler: thrombin activatable fibrinolysis inhibitor, Crimean-Congo hemorrhagic fever, VIRUS-INFECTION, PRIMATE MODELS, TAFI, EBOLA, COAGULATION
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Objectives: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal viral infection. The exact mechanism for hemorrhage remains unknown. Thrombin activatable fibrinolysis inhibitor (TAFI) is a plasma procarboxypeptidase B-like proenzyme and synthesized in the liver, down-regulating fibrinolysis. In this study, we measured the TAR activity in plasma of patients with CCHF to examine the relationship between hemorrhage and the pathogenesis of CCHF.