JOURNAL OF INFECTION, vol.55, no.2, pp.184-187, 2007 (SCI-Expanded)
Article / Article
JOURNAL OF INFECTION
Science Citation Index Expanded (SCI-EXPANDED), Scopus
thrombin activatable fibrinolysis inhibitor, Crimean-Congo hemorrhagic fever, VIRUS-INFECTION, PRIMATE MODELS, TAFI, EBOLA, COAGULATION
Acibadem Mehmet Ali Aydinlar University Affiliated:
Objectives: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal viral infection. The exact mechanism for hemorrhage remains unknown. Thrombin activatable fibrinolysis inhibitor (TAFI) is a plasma procarboxypeptidase B-like proenzyme and synthesized in the liver, down-regulating fibrinolysis. In this study, we measured the TAR activity in plasma of patients with CCHF to examine the relationship between hemorrhage and the pathogenesis of CCHF.