Thrombophilia and inflammatory bowel disease: does factor V mutation have a role?


Over H., Ulgen S., Tuglular T., Tezel A., Avsar E., Geyik G., ...More

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.10, no.10, pp.827-829, 1998 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 10
  • Publication Date: 1998
  • Journal Name: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.827-829
  • Keywords: ulcerative colitis, Crohn's disease, thrombophilia, FV Leiden, activated protein C resistance, ACTIVATED PROTEIN-C, COAGULATION-FACTOR-V, CROHNS-DISEASE, VENOUS THROMBOSIS, BLOOD-COAGULATION, THROMBOEMBOLISM, RESISTANCE, INFARCTION, LEIDEN
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Background An increased tendency for thromboembolism is a well known problem of inflammatory bowel disease (IBD). Microvascular thrombosis has also been claimed as a pathogenic factor in IBD. Recently a point mutation in the gene coding factor V (FV Leiden) has been identified in various thromboembolic diseases, but the role in IBD is unknown.