Thrombophilia and inflammatory bowel disease: does factor V mutation have a role?
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, vol.10, no.10, pp.827-829, 1998 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 10 Issue: 10
- Publication Date: 1998
- Journal Name: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.827-829
- Keywords: ulcerative colitis, Crohn's disease, thrombophilia, FV Leiden, activated protein C resistance, ACTIVATED PROTEIN-C, COAGULATION-FACTOR-V, CROHNS-DISEASE, VENOUS THROMBOSIS, BLOOD-COAGULATION, THROMBOEMBOLISM, RESISTANCE, INFARCTION, LEIDEN
- Acibadem Mehmet Ali Aydinlar University Affiliated: No
Abstract
Background An increased tendency for thromboembolism is a well known problem of inflammatory bowel disease (IBD). Microvascular thrombosis has also been claimed as a pathogenic factor in IBD. Recently a point mutation in the gene coding factor V (FV Leiden) has been identified in various thromboembolic diseases, but the role in IBD is unknown.