Thrombophilia and inflammatory bowel disease: does factor V mutation have a role?

Over H., Ulgen S., Tuglular T., Tezel A., Avsar E., Geyik G., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.10, sa.10, ss.827-829, 1998 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 10
  • Basım Tarihi: 1998
  • Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.827-829
  • Anahtar Kelimeler: ulcerative colitis, Crohn's disease, thrombophilia, FV Leiden, activated protein C resistance, ACTIVATED PROTEIN-C, COAGULATION-FACTOR-V, CROHNS-DISEASE, VENOUS THROMBOSIS, BLOOD-COAGULATION, THROMBOEMBOLISM, RESISTANCE, INFARCTION, LEIDEN
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background An increased tendency for thromboembolism is a well known problem of inflammatory bowel disease (IBD). Microvascular thrombosis has also been claimed as a pathogenic factor in IBD. Recently a point mutation in the gene coding factor V (FV Leiden) has been identified in various thromboembolic diseases, but the role in IBD is unknown.