Hippocampal kindling in rats with absence epilepsy resembles amygdaloid kindling

Akman O., KARSON A., GÜLHAN R., ATEŞ N., Onat F.

EPILEPSY RESEARCH, vol.81, no.2-3, pp.211-219, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 81 Issue: 2-3
  • Publication Date: 2008
  • Doi Number: 10.1016/j.eplepsyres.2008.06.004
  • Journal Name: EPILEPSY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.211-219
  • Keywords: Generalized epilepsy, WAG/Rij, GAERS, Temporal lobe epilepsy model, Partial epilepsy, Kindling resistance, NUCLEUS-REUNIENS-THALAMI, FERRITIN HEAVY-CHAIN, ELECTRICAL-STIMULATION, BIDIRECTIONAL TRANSFER, PERIRHINAL CORTEX, SEIZURES, BRAIN, MECHANISMS, EXPRESSION, MODEL
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Purpose: WAG/Rij and GAERS rats show delays or resistance to secondary generalization of limbic seizures during amygdaloid kindling. In this study, we aimed to evaluate the kindling from a different limbic site, hippocampus, and to compare its effects on spike-and-wave discharges (SWDs) with that of amygdaloid kindling.