Atıf İçin Kopyala
D'Haese J. G., Demir I. E., Kehl T., Winckler J., Giese N. A., Bergmann F., ...Daha Fazla
BMC GASTROENTEROLOGY, cilt.13, 2013 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
13
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Basım Tarihi:
2013
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Doi Numarası:
10.1186/1471-230x-13-14
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Dergi Adı:
BMC GASTROENTEROLOGY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Anahtar Kelimeler:
MFG-E8, Chronic pancreatitis, Fractalkine, Fibrosis, Stellate cells, Pain, DEVELOPMENTAL ENDOTHELIAL LOCUS-1, CX3C CHEMOKINE FRACTALKINE, SMOOTH-MUSCLE-CELLS, ACUTE LUNG INJURY, APOPTOTIC CELLS, STELLATE CELLS, ALLERGIC-ASTHMA, MILK, GROWTH, EXPRESSION
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Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli:
Hayır
Özet
Background: The glycoprotein MFG-E8 mediates phagocytic clearance of apoptotic cells and influences the pathogenesis and progression of inflammatory diseases. MFG-E8 was shown to attenuate the progression of inflammation and to improve survival in septic rats. Accumulating evidence suggests an immunomodulatory link between MFG-E8 and the pro-inflammatory chemokine fractalkine, which may determine the severity of pain, fibrosis, and inflammation in chronic pancreatitis (CP).