Association of missense substitution of A49T and V89L in the SRD5A2 gene with prostate cancer in Turkish patients


Neijmann S. T., Kural A., Tinay I., Livaoglu A., Cevlik T., Turkeri L.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.42, no.1, pp.37-43, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.1515/tjb-2016-0164
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.37-43
  • Keywords: 5 alpha-Reductase gene, Polymorphism, Prostate cancer, SRD5A2 gene, Missense substitution, 5-ALPHA-REDUCTASE TYPE-II, PATHOLOGICAL CHARACTERISTICS, ANDROGEN PATHWAY, RISK, POLYMORPHISMS, INHIBITORS, MEN, AGGRESSIVENESS, EPIDEMIOLOGY, METAANALYSIS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Objective: To determine the association of missense substitution of alanine 49 threonine (A49T) and valine 89 leucine (V89L) in the steroid-5-alpha-reductase type II (SRD5A2) gene with prostate cancer in Turkish patients.