Association of missense substitution of A49T and V89L in the SRD5A2 gene with prostate cancer in Turkish patients

Neijmann, Sebnem; Kural, Alev; Tinay, Ilker; Livaoglu, Ayten; Cevlik, Tulay; Turkeri, LEVENT

doi:10.1515/tjb-2016-0164

Association of missense substitution of A49T and V89L in the SRD5A2 gene with prostate cancer in Turkish patients

Neijmann S. T., Kural A., Tinay I., Livaoglu A., Cevlik T., Turkeri L.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.42, sa.1, ss.37-43, 2017 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 42 Sayı: 1
Basım Tarihi: 2017
Doi Numarası: 10.1515/tjb-2016-0164
Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.37-43
Anahtar Kelimeler: 5 alpha-Reductase gene, Polymorphism, Prostate cancer, SRD5A2 gene, Missense substitution, 5-ALPHA-REDUCTASE TYPE-II, PATHOLOGICAL CHARACTERISTICS, ANDROGEN PATHWAY, RISK, POLYMORPHISMS, INHIBITORS, MEN, AGGRESSIVENESS, EPIDEMIOLOGY, METAANALYSIS
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Objective: To determine the association of missense substitution of alanine 49 threonine (A49T) and valine 89 leucine (V89L) in the steroid-5-alpha-reductase type II (SRD5A2) gene with prostate cancer in Turkish patients.