Akademik Veri Yönetim Sistemi
18th World Congress of Anaesthesiologists (WCA2024), Singapore, Singapur, 3 - 07 Mart 2024, ss.1-4
Introduction/Purpose
During the COVID-19 pandemic, a multisystem inflammatory syndrome in children (MIS-C), a new clinical condition characterized by signs of inflammation and multiorgan dysfunction due to cytokine storm was defined. Morbidity and mortality is increased after cardiac surgery in patients diagnosed with MIS-C syndrome.
In this study, we presented our experience after cardiac surgery of MIS-C syndrome after elective congenital cardiac surgery in our cardiac institution.
Method
All patients with positive serology for SARS-CoV2 (IgG serology) and symptoms, signs, and laboratory markers in favor of a systemic hyperinflammatory condition after uneventful surgery were included in the study. The patients screened for COVID-19 using a nasopharyngeal swab which was reported as negative.
Results
From January 2022-August 2022 we have identified 7 patients diagnosed with MIS-C syndrome. The most common symptoms in these patients were gastrointestinal disorders, coagulation defects, cardiac defects, and respiratory problems. One patient died of multiorgan disorder. Only one patient has received interleukin 1 receptor antagonist (Anakinra) and IVIG and three patients had steroid treatment.
Discussion/Conclusion
Major surgical operations, especially pediatric cardiac surgery, performed after asymptomatic covid 19 infection can trigger cytokine storm and cause MIS-C syndrome in children with varying degrees. It is important to increase the awareness of physicians about the MIS-C disease, which can present with different combinations of different systemic findings so that patients can be diagnosed and treated immidieately. Although there is no family history, it may be important to perform the COVID antibody test together with PCR before major surgical operations to prevent increased mortality and morbidity.