A comparison of the local effectiveness of mitomycin C, aprotinin, and Adcon-L in experimental peridural fibrosis

Kurt G., AYTAR M. H., Dogulu F., Cemil B., Erdem O., Baykaner M. K., ...Daha Fazla

SURGICAL NEUROLOGY, cilt.70, sa.6, ss.608-613, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 70 Sayı: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.surneu.2007.07.071
  • Dergi Adı: SURGICAL NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.608-613
  • Anahtar Kelimeler: Peridural fibrosis, Mitomycin C, Aprotinin, Adcon-L, Failed back surgery syndrome, LUMBAR-DISK HERNIATION, ANTINEOPLASTIC DRUGS, ADHESION FORMATION, SCAR FORMATION, LAMINECTOMY, INHIBITION, PREVENTION, DISKECTOMY, PROPHYLAXIS, LAMINOTOMY
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: Peridural fibrosis and leptomeningeal adhesion formation are among the common causes of FBSS. Various materials have been used to prevent the compressive effect of postoperative PF on neural structures. We investigated and compared the effects of 3 agents-aprotinin, mitomycin C, and Adcon-L-to PF after lumbar laminectomy in rabbits.