Non-Surgical Periodontal Therapy Reduces Saliva Adipokine and Matrix Metalloproteinase Levels in Periodontitis

Ozcan E., Saygun N. I., Serdar M. A., Bengi V. U., Kantarci A.

JOURNAL OF PERIODONTOLOGY, vol.87, no.8, pp.934-943, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 87 Issue: 8
  • Publication Date: 2016
  • Doi Number: 10.1902/jop.2016.160046
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.934-943
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Background: Adipokines enhance the synthesis of proinflammatory cytokines and matrix metalloproteinases (MMPs), which play a role in extracellular matrix degeneration. The aim of this study is to determine the levels of some adipokines, proinflammatory cytokines, and MMPs in the saliva of patients with periodontitis and healthy individuals and to evaluate the changes after non-surgical periodontal therapy (NSPT).