Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study

Koksal, IFTAHAR; YILMAZ, GÜRDAL; PARLAK, Mehmet; Demirdal, Tuna; Kinikli, Sami; Candan, Mehmet; Kaya, Ali; Akhan, Sila; Aydogdu, Ozcan; Turgut, Huseyin; Gurbuz, Yunus; Dagli, Ozgur; Gokal, Ahmet; Guner, Rahmet; Kuruuzum, Ziya; Tarakci, Huseyin; Beslen, Nuri; Erdogan, Seda; Ozdener, Fatih

doi:10.5152/tjg.2018.16597

Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study

Atıf İçin Kopyala

Koksal I., YILMAZ G., PARLAK M., Demirdal T., Kinikli S., Candan M., ...Daha Fazla

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.29, sa.4, ss.464-472, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 29 Sayı: 4
Basım Tarihi: 2018
Doi Numarası: 10.5152/tjg.2018.16597
Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.464-472
Anahtar Kelimeler: Chronic hepatitis C infection, liver fibrosis, FibroTest, APRI, Forns index, Fib-4, non-invasive serum biomarkers, SIMPLE NONINVASIVE INDEX, PLATELET RATIO INDEX, HISTOLOGICAL LESIONS, HCV INFECTION, BIOPSY, PREDICTION, VIRUS, FIBROTEST, CIRRHOSIS, MARKERS
Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background/Aims: The hepatitis C virus (HCV) infection is important cause of chronic hepatitis. Liver biopsy is considered the gold standard for assessment of fibrosis but this procedure is an invasive procedure. We aimed to evaluate the diagnostic efficiency of non-invasive serum biomarkers, separately and in combinations, on liver fibrosis in treatment-naive chronic hepatitis C (CHC) patients.