Diagnostic value of combined serum biomarkers for the evaluation of liver fibrosis in chronic hepatitis C infection: A multicenter, noninterventional, observational study

Koksal I., YILMAZ G., PARLAK M., Demirdal T., Kinikli S., Candan M., ...More

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.29, no.4, pp.464-472, 2018 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.5152/tjg.2018.16597
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.464-472
  • Keywords: Chronic hepatitis C infection, liver fibrosis, FibroTest, APRI, Forns index, Fib-4, non-invasive serum biomarkers, SIMPLE NONINVASIVE INDEX, PLATELET RATIO INDEX, HISTOLOGICAL LESIONS, HCV INFECTION, BIOPSY, PREDICTION, VIRUS, FIBROTEST, CIRRHOSIS, MARKERS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No


Background/Aims: The hepatitis C virus (HCV) infection is important cause of chronic hepatitis. Liver biopsy is considered the gold standard for assessment of fibrosis but this procedure is an invasive procedure. We aimed to evaluate the diagnostic efficiency of non-invasive serum biomarkers, separately and in combinations, on liver fibrosis in treatment-naive chronic hepatitis C (CHC) patients.