Clinically Actionable Strategies for Studying Neural Influences in Cancer

Demir, Ihsan; Reyes, Carmen; Alrawashdeh, Wasfi; CEYHAN, GÜRALP; Deborde, Sylvie; Friess, Helmut; Gorgulu, Kivanc; Istvanffy, Rouzanna; Jungwirth, David; Kuner, Rohini; Maryanovich, Maria; Na'ara, Shorook; Renders, Simon; Saloman, Jami; Scheff, Nicole; Steenfadt, Hendrik; Stupakov, Pavel; Thiel, Vera; Verma, Divij; Yilmaz, Bengi; White, Ruth; Wang, Timothy; Wong, Richard; Frenette, Paul; Gil, Ziv; Davis, Brian

doi:10.1016/j.ccell.2020.05.023

Clinically Actionable Strategies for Studying Neural Influences in Cancer

Demir I. E., Reyes C. M., Alrawashdeh W., CEYHAN G., Deborde S., Friess H., ...More

CANCER CELL, vol.38, no.1, pp.11-14, 2020 (SCI-Expanded, Scopus)

Publication Type: Article / Editorial Material
Volume: 38 Issue: 1
Publication Date: 2020
Doi Number: 10.1016/j.ccell.2020.05.023
Journal Name: CANCER CELL
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE
Page Numbers: pp.11-14
Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.