Clinically Actionable Strategies for Studying Neural Influences in Cancer

Demir I. E., Reyes C. M., Alrawashdeh W., CEYHAN G., Deborde S., Friess H., ...More

CANCER CELL, vol.38, no.1, pp.11-14, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 38 Issue: 1
  • Publication Date: 2020
  • Doi Number: 10.1016/j.ccell.2020.05.023
  • Journal Name: CANCER CELL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.11-14
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes


Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic.