The role of biomarkers in the diagnosis of periprosthetic joint infection

Shahi A., Parvizi J.

EFORT OPEN REVIEWS, cilt.1, sa.7, ss.275-278, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1 Sayı: 7
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1302/2058-5241.1.160019
  • Dergi Adı: EFORT OPEN REVIEWS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.275-278
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

The role of serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) as the first line for evaluating a patient with periprosthetic joint infection (PJI) has been debunked. We are living in the era of biomarkers for the diagnosis of PJI, and to that effect, several biomarkers have been introduced such as synovial fluid alpha defensin and leukocyte esterase. The synovial fluid leukocyte esterase test has a low cost, is accessible, and has provided promising results for diagnosing PJI. There is an urgent need for an accurate and reliable serum biomarker for diagnosing patients with PJI.