Effects of L-thyroxine Replacement Therapy on Carotid Intima-media Thickness in Patients with Primary Hypothyroidism

Cakal E., Turgut A. T., Demirbas B., Ozkaya M., Cakal B., Serter R., ...Daha Fazla

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, cilt.117, sa.6, ss.294-300, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 117 Sayı: 6
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1055/s-0028-1085998
  • Dergi Adı: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.294-300
  • Anahtar Kelimeler: thyroxine, primary hypothyroidism, carotid artery, ultrasonography, C-REACTIVE PROTEIN, CARDIOVASCULAR RISK-FACTORS, LOW-DENSITY-LIPOPROTEIN, CORONARY-HEART-DISEASE, SUBCLINICAL HYPOTHYROIDISM, ATHEROSCLEROSIS RISK, DOUBLE-BLIND, HOMOCYSTEINE, ARTERY, LEVOTHYROXINE
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: in hypothyroid patients, the risk for cardiovascular disease is higher and ultrasonography (US) demonstrates that the carotid intima-media thickness (CIMT) is significantly increased. We hypothesized that L-thyroxine replacement therapy might be able to reverse the process associated with increase in CIMT in patients with primary hypothyroidism.