Comparison of Clinical Progress of Covid-19 Patients Followed in the Hospital by Vaccination Status


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YİĞİT S. E., GÖKMEN İ. B., OKUTURLAR Y., KÖKSAL İ.

Turkish Journal of Internal Medicine, cilt.4, ss.12-16, 2022 (Hakemli Dergi)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.46310/tjim.1073683
  • Dergi Adı: Turkish Journal of Internal Medicine
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.12-16
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Background Although COVID-19 vaccines cannot prevent infection with SARS-CoV-2, they do allow infected people to have a milder illness. In unvaccinated people, the disease progresses more severely and the disease can be fatal. Both inactivated (Sinovac) and mRNA (BioNTech-Pfizer) vaccines are used in Turkey. In this retrospective study, clinical course, radiological involvement and some laboratory parameters that are important for COVID-19 were compared in unvaccinated and vaccinated patients who were infected and followed up in the hospital. Material and Methods Patients between the ages of 17-95 who were hospitalized in the COVID-19 isolation wards between June 2021 and November 2021 were included in the study. Various data of patients were scanned retrospectively from the hospital registry system. Results While there was no difference in the mean age, highest fibrinogen, D-dimer, ferritin, creatinine, interleukin-6 (IL-6) values and COVID-19 PCR test negative times besides antibody levels, Group 2 (7.8 days) was found to be discharged significantly earlier than Group 1 (12.69 days) (p=0.046). There was a significant difference in low-dose thoracic computed tomography (CT) findings between the two groups (p=0.023). Conclusions Our study results showed that regardless of the type of vaccine, vaccination against COVID-19 reduces hospitalization rates, length of stay and prevents serious involvement in the lungs.