Cardiovascular regulation through hypothalamic GABA(A) receptors in a genetic absence epilepsy model in rat.

Aker R. G. , Onat F. Y.

Epilepsia, vol.43, no.2, pp.107-14, 2002 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 2
  • Publication Date: 2002
  • Doi Number: 10.1046/j.1528-1157.2002.45200.x
  • Journal Name: Epilepsia
  • Journal Indexes: Science Citation Index Expanded
  • Page Numbers: pp.107-14


Purpose: gamma-Aminobutyric acid (GABA) plays a vital role in both central cardiovascular homeostasis and pathogenesis of epilepsy. Epilepsy affects autonomic nervous system functions. In this study, we aimed to clarify the role of GABA(A) receptors in hypothalamic cardiovascular regulation in a genetically determined animal model of absence epilepsy.