Effect of Alprazolam on Redox Status in Renal Transplantation Donors and Recipients.

Can M., Kocyigit O. I., Aksu U., ÖZER A., Toraman F.

Annals of transplantation, vol.22, pp.354-360, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22
  • Publication Date: 2017
  • Doi Number: 10.12659/aot.903695
  • Journal Name: Annals of transplantation
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.354-360
  • Keywords: Alprazolam, Antioxidants, Kidney Transplantation, Premedication, OXIDATIVE STRESS, SIALIC-ACID, PLASMA, HEMODIALYSIS
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Background: Benzodiazepines are the most popular premedication drugs thought to act through the GABA/benzodiazepine receptor complex and alprazolam is one of the most potent benzodiazepines that have a quick onset. While there is a growing body of evidence supporting alprazolam in the amelioration of redox status in animals, no study has been performed concerning its antioxidant activity in humans. The purpose of this investigation was to determine the effect of alprazolam on redox status.