Functionally expanded polytetrafluoroethylene (ePTFE) grafts have not been preferred as a coronary conduit due to their low patency rates. In this article, we report a 69-year-old male case who was operated 10 years ago with an ePTFE coronary conduit. During percutaneous intervention of coronary conduit, perforation was observed and patient was operated immediately. Usage of ePTFE graft was confirmed during surgery. This case report produces an evidence for the long-term patency of ePTFE graft. It also shows a higher complication risk for percutaneous ePTFE grafts compared to the native autologous conduits.