Comparing glutamatergic neuron population in the mediodorsal thalamic nucleus of genetic absence epilepsy rats from strasbourg (GAERS) and normal control Wistar rats

Cavdar S., Ozgur M., KİRAZLI Ö., Karahuseyinoglu S., Onat F.

JOURNAL OF CHEMICAL NEUROANATOMY, cilt.77, ss.93-99, 2016 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jchemneu.2016.05.009
  • Dergi Adı: JOURNAL OF CHEMICAL NEUROANATOMY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.93-99
  • Anahtar Kelimeler: Glutamate, Mediodorsal thalamic nucleus, Absence epilepsy, Quantification immunohistochemistry, GENERALIZED PENICILLIN EPILEPSY, MAL-LIKE SEIZURES, WAVE DISCHARGES, NONCONVULSIVE EPILEPSY, CORTEX, MODEL, SPIKE, MECHANISMS, SCHIZOPHRENIA, POSTMORTEM
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

An imbalance between GABAergic inhibition and glutamatergic excitation is suspected to play a role in the genesis of epileptic processes. In the present study we quantified the number of glutamate+ve neurons in the mediodorsal thalamic nucleus (MD) of genetic absence epilepsy rats from Strasbourg (GAERS) and compared these with values for normal Wistar rats.