Preparation of amphiphilic glycerol-substituted zinc phthalocyanines using copper-free Sonogashira cross-coupling in aqueous medium

DUMOULIN F., Ali H., Ahsen V., van Lier J. E.

TETRAHEDRON LETTERS, cilt.52, sa.34, ss.4395-4397, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 34
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.tetlet.2011.06.010
  • Dergi Adı: TETRAHEDRON LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.4395-4397
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Palladium-catalyzed copper-free Sonogashira cross-coupling reactions were performed on a protected and unprotected monoiodotriglycerol substituted Zn(II) phthalocyanine with various alkynes in organic and aqueous medium. From the silyl protected alkyne derivative, a protected homo coupled dimeric product was also prepared using Glaser coupling. All products were purified by reverse phase HPLC and the assigned structures were confirmed by mass and UV-vis spectroscopy. (C) 2011 Elsevier Ltd. All rights reserved.