Biosensor implementation for cardiovascular risk marker analysis

Gul O., Inceturkmen E., Kutuk O., Basaga H., Sezerman U., Gurbuz Y.

4th IEEE Conference on Sensors, Irvine, England, 31 October - 03 November 2005, pp.303-305, (Full Text) identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Doi Number: 10.1109/icsens.2005.1597696
  • City: Irvine
  • Country: England
  • Page Numbers: pp.303-305
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

In this paper we presented the detection of cardiovascular marker protein set in the form of sandwiched-antibody microarrays. The antibody set consist of C-Reactive Protein, Fatty Acid Binding Protein, Myoglobin, D-Dimer, Troponin T protein, known cardiovascular risk markers in human serum. Chemically-modified glass substrate surfaces were used as solid support for immobilization of sandwiched, anti body-antigen-antibody structures. An optical scanner system was used for the detection of fluorescent-labeled, captured antibody set. We have shown that the proposed structure/process is capable of detecting 1 mu g/ml concentration of antigens, used in this study.