Biosensor implementation for cardiovascular risk marker analysis

Gul O., Inceturkmen E., Kutuk O., Basaga H., Sezerman U., Gurbuz Y.

4th IEEE Conference on Sensors, Irvine, İngiltere, 31 Ekim - 03 Kasım 2005, ss.303-305 identifier identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Doi Numarası: 10.1109/icsens.2005.1597696
  • Basıldığı Şehir: Irvine
  • Basıldığı Ülke: İngiltere
  • Sayfa Sayıları: ss.303-305
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

In this paper we presented the detection of cardiovascular marker protein set in the form of sandwiched-antibody microarrays. The antibody set consist of C-Reactive Protein, Fatty Acid Binding Protein, Myoglobin, D-Dimer, Troponin T protein, known cardiovascular risk markers in human serum. Chemically-modified glass substrate surfaces were used as solid support for immobilization of sandwiched, anti body-antigen-antibody structures. An optical scanner system was used for the detection of fluorescent-labeled, captured antibody set. We have shown that the proposed structure/process is capable of detecting 1 mu g/ml concentration of antigens, used in this study.