Does L-carnitine increase serum TNF -alpha and IGF-1 during liver regeneration in the rat?

Pehlivan M., Coskun A., Zengin A., Aslaner A., Yavuz T.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.39, no.6, pp.875-880, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 6
  • Publication Date: 2009
  • Doi Number: 10.3906/sag-0804-20
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.875-880
  • Keywords: Liver regeneration, partial hepatectomy, L-carnitine, TNF-alpha, IGF-1, TUMOR-NECROSIS-FACTOR, PARTIAL-HEPATECTOMY, GROWTH-FACTORS, EXPRESSION, RECEPTORS, INSULIN
  • Acibadem Mehmet Ali Aydinlar University Affiliated: Yes

Abstract

Aim: We sought to evaluate the effect of L-carnitine administration on the levels of IGF-1, TNF-alpha, and lipid peroxidation during hepatic regeneration for up to 72 h in an experimental partial hepatic resection rat model.