The prevalence of hepatic granulomas in chronic hepatitis C

Ozaras R., Tahan V., Mert A., Uraz S., Kanat M., TABAK Ö. F. , ...More

JOURNAL OF CLINICAL GASTROENTEROLOGY, vol.38, no.5, pp.449-452, 2004 (Journal Indexed in SCI) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 5
  • Publication Date: 2004
  • Doi Number: 10.1097/00004836-200405000-00011
  • Page Numbers: pp.449-452
  • Keywords: hepatic granuloma, chronic hepatitis C, interferon, LIVER-BIOPSY, INTERFERON, DIAGNOSIS


Objectives: Hepatic granulomas are not usual findings in chronic hepatitis C. A few studies addressing the frequency of hepatic granulomas in chronic hepatitis C reported it as less than 10%. The presence of it has been suggested to predict a favorable response to interferon treatment. Also, case reports described the development of hepatic granulomas after interferon treatment. In this study, we aimed to detect the prevalence of hepatic granulomas in chronic hepatitis C and to identify the causes other than chronic hepatitis C, if present, to search whether there is an association between the presence of granuloma and response to interferon treatment and also to see whether interferon leads to the formation of hepatic granulomas.