Presence of high grade tertiary Gleason pattern upgrades the Gleason sum score and is inversely associated with biochemical recurrence-free survival

Turker P., Bas E., BOZKURT S., Gunlusoy B., Sezgin A., Postaci H., ...More

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, vol.31, no.1, pp.93-98, 2013 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1016/j.urolonc.2010.10.009
  • Journal Name: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.93-98
  • Keywords: Prostate cancer pathology, Tertiary Gleason, Survival, RADICAL PROSTATECTOMY SPECIMENS, PROGNOSTIC-SIGNIFICANCE, PROSTATIC ADENOCARCINOMA, MULTIVARIATE-ANALYSIS, PATHOLOGICAL STAGE, CANCER, PROGRESSION, PREDICTION, CARCINOMA, MEN
  • Acibadem Mehmet Ali Aydinlar University Affiliated: No

Abstract

Objectives: Tumor heterogeneity is a common finding and led to realization of a tertiary Gleason component (TGC) in prostate cancer. In an attempt to further investigate its prognostic value, we analyzed the association of tertiary Gleason pattern in Gleason score <= 7 tumors with pathologic stage and biochemical disease-free survival.