IRANIAN JOURNAL OF NEUROLOGY, vol.14, no.3, pp.164-167, 2015 (Peer-Reviewed Journal)
Background: Besides the well-known adverse effects of valproate (VPA), disorders related to male reproductive functions have been reported. Furthermore, only a limited number of previous studies have reported the relationship between VPA dose and impairment of the hormonal axis and semen quality. A patient with reversible changes that occurred in the sperm parameters after a dose increment of VPA.