Alterations in semen parameters in men with epilepsy treated with valproate

Kose-Ozlece H., Ilik F., Cecen K., Huseyinoglu N., Serim A.

IRANIAN JOURNAL OF NEUROLOGY, cilt.14, sa.3, ss.164-167, 2015 (Hakemli Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 3
  • Basım Tarihi: 2015
  • Dergi Adı: IRANIAN JOURNAL OF NEUROLOGY
  • Sayfa Sayıları: ss.164-167
  • Anahtar Kelimeler: Valproate, Male Infertility, Epilepsy, Antiepileptic Drugs, Reproductive Dysfunction
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Background: Besides the well-known adverse effects of valproate (VPA), disorders related to male reproductive functions have been reported. Furthermore, only a limited number of previous studies have reported the relationship between VPA dose and impairment of the hormonal axis and semen quality. A patient with reversible changes that occurred in the sperm parameters after a dose increment of VPA.