Using intraoperative dynamic contrast-enhanced T1-weighted MRI to identify residual tumor in glioblastoma surgery

ÖZDUMAN K., Yildiz E., Dincer A., Sav A., Pamir M. N.

JOURNAL OF NEUROSURGERY, cilt.120, sa.1, ss.60-66, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 120 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3171/2013.9.jns121924
  • Dergi Adı: JOURNAL OF NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.60-66
  • Anahtar Kelimeler: intraoperative magnetic resonance imaging, high-grade glioma, dynamic contrast imaging, glioblastoma, oncology, LOW-GRADE GLIOMA, MALIGNANT GLIOMA, KINETIC-ANALYSIS, BRAIN-TUMORS, BLOOD-VOLUME, RESECTION, GUIDANCE, MULTIFORME, SURVIVAL, EXTENT
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Evet

Özet

Object. The goal of surgery in high-grade gliomas is to maximize the resection of contrast-enhancing tumor without causing additional neurological deficits. Intraoperative MRI improves surgical results. However, when using contrast material intraoperatively, it may be difficult to differentiate between surgically induced enhancement and residual tumor. The purpose of this study was to assess the usefulness of intraoperative dynamic contrast-enhanced T1-weighted MRI to guide this differential diagnosis and test it against tissue histopathology.