The Effect of Ursodeoxycholic Acid and Piperacillin-Tazobactam on Acute Renal Failure Associated with Obstructive Jaundice in Experimental Models

Gonenc M., Kapan M., Erdamar S., Uzun H., Kapan S., Goksoy E.

MEDICAL JOURNAL OF BAKIRKOY, cilt.6, sa.3, ss.91-96, 2010 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 3
  • Basım Tarihi: 2010
  • Dergi Adı: MEDICAL JOURNAL OF BAKIRKOY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.91-96
  • Anahtar Kelimeler: Obstructive jaundice, renal failure, endotoxemia, ursodeoxycholic acid, piperacillin-tazobactam
  • Acıbadem Mehmet Ali Aydınlar Üniversitesi Adresli: Hayır

Özet

Objective: Acute renal failure associated with obstructive jaundice is still a major clinical problem, and has yet not been completely understood. Many studies showed that one of the most important features of the process was endotoxemia and subsequent sepsis. We investigated the effects of ursodeoxycholic acid and piperacillin-tazobactam on acute renal failure associated with obstructive jaundice.