Biological variation data for lipid cardiovascular risk assessment biomarkers. A systematic review applying the biological variation data critical appraisal checklist (BIVAC)

Diaz-Garzon J., Fernandez Calle P., Minchinela J., Aarsand A. K. , Bartlett W. A. , Aslan B., ...Daha Fazla

CLINICA CHIMICA ACTA, cilt.495, ss.467-475, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 495
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.cca.2019.05.013
  • Sayfa Sayıları: ss.467-475


Background: Biological variation (BV) data can be used to set analytical performance specifications (APS) for lipid assays. Poor performance will impact upon the efficacy of international guidelines for cardiovascular risk assessment (CVR) and relevant clinical decision limits. This systematic review applies the Biological Variation Data Critical Appraisal Checklist (BIVAC) to published studies of BV of CVR biomarkers enabling metanalysis of the data.